Gene: Syngap1 (synaptic Ras GTPase activating protein 1) Rattus norvegicus
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Symbol: Syngap1
Name: synaptic Ras GTPase activating protein 1
Description: ENCODES a protein that exhibits GTPase activator activity; protein kinase binding; INVOLVED IN negative regulation of Ras protein signal transduction; regulation of synaptic plasticity; dendrite development (ortholog); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; ASSOCIATED WITH Ataxia (ortholog); autism spectrum disorder (ortholog); Autistic Disorder (ortholog); FOUND IN postsynaptic density of dendrite; synapse; dendritic shaft (ortholog); INTERACTS WITH ammonium chloride; bis(2-ethylhexyl) phthalate; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: neuronal RasGAP; p135 SynGAP; ras GTPase-activating protein SynGAP; ras/Rap GTPase-activating protein SynGAP; synaptic Ras GTPase activating protein 1 homolog; synaptic Ras GTPase activating protein 1 homolog (rat); synaptic Ras GTPase-activating protein 1; synaptic Ras-GAP 1; Syngap
Orthologs:
Homo sapiens (human) : SYNGAP1 (synaptic Ras GTPase activating protein 1)  HGNC
Mus musculus (house mouse) : Syngap1 (synaptic Ras GTPase activating protein 1 homolog (rat))  MGI
Chinchilla lanigera (long-tailed chinchilla) : Syngap1 (synaptic Ras GTPase activating protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SYNGAP1 (synaptic Ras GTPase activating protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Syngap1 (synaptic Ras GTPase activating protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0205,535,434 - 5,564,657 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0207,594,614 - 7,623,865 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4205,178,523 - 5,208,449 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1205,191,049 - 5,207,973 (+)NCBI
Celera206,608,780 - 6,637,810 (+)NCBI
Cytogenetic Map20p12NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Syngap1
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 621090
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-07-11
Status: ACTIVE