Gene: Syngap1 (synaptic Ras GTPase activating protein 1) Rattus norvegicus
Symbol: Syngap1
Name: synaptic Ras GTPase activating protein 1
Description: ENCODES a protein that exhibits GTPase activator activity; protein kinase binding; INVOLVED IN negative regulation of Ras protein signal transduction; regulation of synaptic plasticity; dendrite development (ortholog); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; ASSOCIATED WITH Autistic Disorder (ortholog); autistic disorder (ortholog); Cerebellar Ataxia (ortholog); FOUND IN postsynaptic density; synapse; dendritic shaft (ortholog); INTERACTS WITH ammonium chloride; bis(2-ethylhexyl) phthalate; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: neuronal RasGAP; p135 SynGAP; ras GTPase-activating protein SynGAP; ras/Rap GTPase-activating protein SynGAP; synaptic Ras GTPase activating protein 1 homolog; synaptic Ras GTPase activating protein 1 homolog (rat); synaptic Ras GTPase-activating protein 1; synaptic Ras-GAP 1; Syngap
Homo sapiens (human) : SYNGAP1 (synaptic Ras GTPase activating protein 1)  HGNC  AGR
Mus musculus (house mouse) : Syngap1 (synaptic Ras GTPase activating protein 1 homolog (rat))  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Syngap1 (synaptic Ras GTPase activating protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SYNGAP1 (synaptic Ras GTPase activating protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Syngap1 (synaptic Ras GTPase activating protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0205,535,434 - 5,564,657 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0207,594,614 - 7,623,865 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,178,523 - 5,208,449 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1205,191,049 - 5,207,973 (+)NCBI
Celera206,608,780 - 6,637,810 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Syngap1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621090
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE