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Gene: Tgs1 (trimethylguanosine synthase 1) Rattus norvegicus

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Symbol:

Tgs1

Name:

trimethylguanosine synthase 1

RGD ID:

1309953

Description:

Predicted to enable RNA cap trimethylguanosine synthase activity. Predicted to be involved in 7-methylguanosine cap hypermethylation. Predicted to be located in cytosol. Predicted to be active in nucleus. Orthologous to human TGS1 (trimethylguanosine synthase 1); PARTICIPATES IN RNA transport pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cap-specific guanine-N(2) methyltransferase; LOC312947; Ncoa6ip; nuclear receptor coactivator 6 interacting protein; nuclear receptor coactivator 6-interacting protein; PIMT; PIPMT; PRIP-interacting protein with methyltransferase motif; trimethylguanosine synthase; trimethylguanosine synthase homolog; trimethylguanosine synthase homolog (S. cerevisiae)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TGS1 (trimethylguanosine synthase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tgs1 (trimethylguanosine synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tgs1 (trimethylguanosine synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TGS1 (trimethylguanosine synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TGS1 (trimethylguanosine synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tgs1 (trimethylguanosine synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TGS1 (trimethylguanosine synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TGS1 (trimethylguanosine synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tgs1 (trimethylguanosine synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	C11orf42 (chromosome 11 open reading frame 42)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	TGS1 (trimethylguanosine synthase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tgs1 (trimethylguanosine synthase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tgs1 (trimethylguanosine synthase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	lyn (LYN proto-oncogene, Src family tyrosine kinase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T08G11.4	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	TGS1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Tgs1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tgs1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	21,322,492 - 21,356,017 (+)	NCBI		GRCr8
mRatBN7.2	5	16,524,864 - 16,558,399 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	16,524,874 - 16,558,399 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	18,773,465 - 18,806,565 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	20,371,954 - 20,405,057 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	20,123,429 - 20,156,541 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	16,413,356 - 16,446,881 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	16,413,356 - 16,446,881 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	21,194,620 - 21,228,145 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	16,818,391 - 16,851,916 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	16,818,178 - 16,850,318 (+)	NCBI
Celera	5	15,891,134 - 15,924,317 (+)	NCBI		Celera
Cytogenetic Map	5	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tgs1	Rat	basal cell carcinoma		ISO	RGD:1320573	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:36428691

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tgs1	Rat	1,2-dichloroethane	decreases expression	ISO	RGD:1320574	6480464	ethylene dichloride results in decreased expression of TGS1 mRNA	CTD	PMID:28960355
Tgs1	Rat	17alpha-ethynylestradiol	affects expression	ISO	RGD:1320574	6480464	Ethinyl Estradiol affects the expression of TGS1 mRNA	CTD	PMID:17555576
Tgs1	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1320574	6480464	Tetrachlorodibenzodioxin affects the expression of TGS1 mRNA	CTD	PMID:21570461
Tgs1	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of TGS1 mRNA	CTD	PMID:33387578
Tgs1	Rat	4-vinylcyclohexene dioxide	affects expression	ISO	RGD:1320574	6480464	4-vinyl-1-cyclohexene dioxide affects the expression of TGS1 mRNA	CTD	PMID:20829426
Tgs1	Rat	acrylamide	increases expression	EXP		6480464	Acrylamide results in increased expression of TGS1 mRNA	CTD	PMID:28959563
Tgs1	Rat	aflatoxin B1	increases expression	ISO	RGD:1320574	6480464	Aflatoxin B1 results in increased expression of TGS1 mRNA	CTD	PMID:19770486
Tgs1	Rat	aflatoxin B1	decreases methylation	ISO	RGD:1320573	6480464	Aflatoxin B1 results in decreased methylation of TGS1 gene	CTD	PMID:27153756
Tgs1	Rat	aflatoxin B1	increases expression	ISO	RGD:1320573	6480464	Aflatoxin B1 results in increased expression of TGS1 mRNA	CTD	PMID:22100608
Tgs1	Rat	all-trans-retinoic acid	decreases expression	ISO	RGD:1320573	6480464	Tretinoin results in decreased expression of TGS1 mRNA	CTD	PMID:33167477
Tgs1	Rat	aristolochic acid A	decreases expression	ISO	RGD:1320573	6480464	aristolochic acid I results in decreased expression of TGS1 mRNA	CTD	PMID:33212167
Tgs1	Rat	arsane	multiple interactions	ISO	RGD:1320573	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TGS1 more ...	CTD	PMID:39836092
Tgs1	Rat	arsenic atom	multiple interactions	ISO	RGD:1320573	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TGS1 more ...	CTD	PMID:39836092
Tgs1	Rat	benzo[a]pyrene	increases expression	ISO	RGD:1320574	6480464	Benzo(a)pyrene results in increased expression of TGS1 mRNA	CTD	PMID:22228805
Tgs1	Rat	benzo[a]pyrene diol epoxide I	decreases expression	ISO	RGD:1320573	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TGS1 mRNA	CTD	PMID:20018196
Tgs1	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of TGS1 mRNA	CTD	PMID:25181051
Tgs1	Rat	bisphenol A	increases methylation	ISO	RGD:1320573	6480464	bisphenol A results in increased methylation of TGS1 gene	CTD	PMID:31601247
Tgs1	Rat	bisphenol A	multiple interactions	ISO	RGD:1320573	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of TGS1 gene	CTD	PMID:31601247
Tgs1	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of TGS1 mRNA	CTD	PMID:30816183\|PMID:32528016
Tgs1	Rat	caffeine	increases phosphorylation	ISO	RGD:1320573	6480464	Caffeine results in increased phosphorylation of TGS1 protein	CTD	PMID:35688186
Tgs1	Rat	chlorpyrifos	decreases expression	ISO	RGD:1320574	6480464	Chlorpyrifos results in decreased expression of TGS1 mRNA	CTD	PMID:37019170
Tgs1	Rat	cisplatin	increases expression	ISO	RGD:1320573	6480464	Cisplatin results in increased expression of TGS1 mRNA	CTD	PMID:27392435
Tgs1	Rat	colforsin daropate hydrochloride	increases expression	ISO	RGD:1320573	6480464	Colforsin results in increased expression of TGS1 mRNA	CTD	PMID:16751804
Tgs1	Rat	coumarin	decreases phosphorylation	ISO	RGD:1320573	6480464	coumarin results in decreased phosphorylation of TGS1 protein	CTD	PMID:35688186
Tgs1	Rat	Dibutyl phosphate	affects expression	ISO	RGD:1320573	6480464	di-n-butylphosphoric acid affects the expression of TGS1 mRNA	CTD	PMID:37042841
Tgs1	Rat	epoxiconazole	decreases expression	ISO	RGD:1320574	6480464	epoxiconazole results in decreased expression of TGS1 mRNA	CTD	PMID:35436446
Tgs1	Rat	ethyl methanesulfonate	increases expression	ISO	RGD:1320573	6480464	Ethyl Methanesulfonate results in increased expression of TGS1 mRNA	CTD	PMID:23649840
Tgs1	Rat	formaldehyde	decreases expression	ISO	RGD:1320573	6480464	Formaldehyde results in decreased expression of TGS1 mRNA	CTD	PMID:20655997
Tgs1	Rat	FR900359	affects phosphorylation	ISO	RGD:1320573	6480464	FR900359 affects the phosphorylation of TGS1 protein	CTD	PMID:37730182
Tgs1	Rat	fulvestrant	multiple interactions	ISO	RGD:1320573	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of TGS1 gene	CTD	PMID:31601247
Tgs1	Rat	indometacin	decreases expression	ISO	RGD:1320573	6480464	Indomethacin results in decreased expression of TGS1 mRNA	CTD	PMID:16984733
Tgs1	Rat	methotrexate	affects expression	ISO	RGD:1320574	6480464	Methotrexate affects the expression of TGS1 mRNA	CTD	PMID:18502557
Tgs1	Rat	methyl methanesulfonate	increases expression	ISO	RGD:1320573	6480464	Methyl Methanesulfonate results in increased expression of TGS1 mRNA	CTD	PMID:23649840
Tgs1	Rat	methylmercury chloride	increases expression	ISO	RGD:1320573	6480464	methylmercuric chloride results in increased expression of TGS1 mRNA	CTD	PMID:28001369
Tgs1	Rat	paracetamol	increases expression	ISO	RGD:1320573	6480464	Acetaminophen results in increased expression of TGS1 mRNA	CTD	PMID:22230336
Tgs1	Rat	phenobarbital	decreases expression	ISO	RGD:1320574	6480464	Phenobarbital results in decreased expression of TGS1 mRNA	CTD	PMID:23091169
Tgs1	Rat	sodium arsenite	increases expression	ISO	RGD:1320574	6480464	sodium arsenite results in increased expression of TGS1 mRNA	CTD	PMID:16014739\|PMID:32068019
Tgs1	Rat	sodium arsenite	multiple interactions	ISO	RGD:1320573	6480464	[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TGS1 more ...	CTD	PMID:39836092
Tgs1	Rat	temozolomide	increases expression	ISO	RGD:1320573	6480464	Temozolomide results in increased expression of TGS1 mRNA	CTD	PMID:31758290
Tgs1	Rat	tetrachloromethane	increases expression	EXP		6480464	Carbon Tetrachloride results in increased expression of TGS1 mRNA	CTD	PMID:31150632
Tgs1	Rat	thioacetamide	increases expression	EXP		6480464	Thioacetamide results in increased expression of TGS1 mRNA	CTD	PMID:34492290
Tgs1	Rat	triphenyl phosphate	affects expression	ISO	RGD:1320573	6480464	triphenyl phosphate affects the expression of TGS1 mRNA	CTD	PMID:37042841
Tgs1	Rat	troglitazone	decreases expression	ISO	RGD:1320574	6480464	troglitazone results in decreased expression of TGS1 mRNA	CTD	PMID:28973697
Tgs1	Rat	tungsten	decreases expression	ISO	RGD:1320574	6480464	Tungsten results in decreased expression of TGS1 mRNA	CTD	PMID:30912803

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tgs1	Rat	7-methylguanosine cap hypermethylation	involved_in	ISO	RGD:1320573	1624291	PMID:16687569	RGD	PMID:16687569
Tgs1	Rat	7-methylguanosine cap hypermethylation	involved_in	IEA	InterPro:IPR019012	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Tgs1	Rat	7-methylguanosine cap hypermethylation	involved_in	IBA	PANTHER:PTN000380808\|PomBase:SPAC2G11.15c\|SGD:S000006078\|TAIR:locus:1005716684\|UniProtKB:Q96RS0	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tgs1	Rat	methylation	involved_in	IEA	UniProtKB-KW:KW-0489	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Tgs1	Rat	RNA methylation	involved_in	IEA	InterPro:IPR019012	1600115	GO_REF:0000002	InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tgs1	Rat	Cajal body	located_in	IEA	UniProtKB-SubCell:SL-0031	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Tgs1	Rat	cytoplasm	located_in	ISO	RGD:1320573	1624291	PMID:12943661	RGD	PMID:12943661
Tgs1	Rat	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Tgs1	Rat	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Tgs1	Rat	cytosol	located_in	ISO	RGD:1320573	1624291		RGD	GO_REF:0000052
Tgs1	Rat	nucleolus	located_in	IEA	UniProtKB-SubCell:SL-0188	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Tgs1	Rat	nucleus	located_in	ISO	RGD:1320573	1624291	PMID:12943661	RGD	PMID:12943661
Tgs1	Rat	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Tgs1	Rat	nucleus	is_active_in	IBA	PANTHER:PTN000380809\|PomBase:SPAC2G11.15c\|SGD:S000006078\|TAIR:locus:1005716684\|UniProtKB:Q96RS0	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tgs1	Rat	methyltransferase activity	enables	IEA	UniProtKB-KW:KW-0489	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Tgs1	Rat	methyltransferase activity	enables	IEA	InterPro:IPR019012	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Tgs1	Rat	protein binding	enables	ISO	RGD:1320573	1624291	UniProtKB:P22087\|UniProtKB:P36508\|UniProtKB:Q86UR1-2\|UniProtKB:Q9Y2X3 PMID:21522132, PMID:28514442, PMID:32296183, PMID:33961781, PMID:35271311	RGD	PMID:21522132\|PMID:28514442\|PMID:32296183\|PMID:33961781\|PMID:35271311
Tgs1	Rat	protein binding	enables	ISO	RGD:1320574	1624291	UniProtKB:P97462 PMID:12943661	RGD	PMID:12943661
Tgs1	Rat	RNA cap trimethylguanosine synthase activity	enables	ISO	RGD:1320573	1624291	PMID:16687569	RGD	PMID:16687569
Tgs1	Rat	RNA cap trimethylguanosine synthase activity	enables	IBA	PANTHER:PTN000380808\|PomBase:SPAC2G11.15c\|TAIR:locus:1005716684\|UniProtKB:Q96RS0	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tgs1	Rat	RNA cap trimethylguanosine synthase activity	enables	IEA	RHEA:78471\|RHEA:78475\|RHEA:78479\|RHEA:78507	1600115	GO_REF:0000116	RHEA	GO_REF:0000116
Tgs1	Rat	transferase activity	enables	IEA	UniProtKB-KW:KW-0808	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Imported Annotations - KEGG (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tgs1	Rat	RNA transport pathway		IEA		6907045		KEGG	rno:03013

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:12943661	PMID:15057822	PMID:16687569	PMID:22664934	PMID:37175791

Tgs1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	21,322,492 - 21,356,017 (+)	NCBI		GRCr8
mRatBN7.2	5	16,524,864 - 16,558,399 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	16,524,874 - 16,558,399 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	18,773,465 - 18,806,565 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	20,371,954 - 20,405,057 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	20,123,429 - 20,156,541 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	16,413,356 - 16,446,881 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	16,413,356 - 16,446,881 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	21,194,620 - 21,228,145 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	16,818,391 - 16,851,916 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	16,818,178 - 16,850,318 (+)	NCBI
Celera	5	15,891,134 - 15,924,317 (+)	NCBI		Celera
Cytogenetic Map	5	q12	NCBI

TGS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	55,773,446 - 55,826,445 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	55,773,446 - 55,826,445 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	56,686,005 - 56,739,004 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	56,848,345 - 56,900,559 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	56,848,254 - 56,900,557	NCBI
Celera	8	52,677,058 - 52,729,766 (+)	NCBI		Celera
Cytogenetic Map	8	q12.1	NCBI
HuRef	8	52,154,245 - 52,206,403 (+)	NCBI		HuRef
CHM1_1	8	56,737,385 - 56,789,600 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	56,150,498 - 56,203,496 (+)	NCBI		T2T-CHM13v2.0

Tgs1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	3,574,875 - 3,616,624 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	3,574,875 - 3,616,619 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	3,574,841 - 3,616,624 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	3,574,875 - 3,616,619 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	3,502,026 - 3,543,771 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	3,502,045 - 3,543,771 (+)	NCBI		MGSCv36	mm8
Celera	4	3,520,719 - 3,562,191 (+)	NCBI		Celera
Cytogenetic Map	4	A1	NCBI
cM Map	4	1.99	NCBI

Tgs1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955454	14,896,085 - 14,934,414 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955454	14,896,085 - 14,937,678 (+)	NCBI	ChiLan1.0	ChiLan1.0

TGS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	71,425,861 - 71,477,581 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	47,150,469 - 47,202,335 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	52,214,283 - 52,266,439 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	49,585,920 - 49,637,832 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	49,585,889 - 49,637,832 (+)	Ensembl	panpan1.1		panPan2

TGS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	7,241,050 - 7,281,811 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	7,241,237 - 7,280,500 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	7,553,785 - 7,594,760 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	7,314,445 - 7,355,478 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	7,314,851 - 7,355,474 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	7,328,877 - 7,369,857 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	7,461,655 - 7,502,629 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	7,738,103 - 7,779,317 (+)	NCBI		UU_Cfam_GSD_1.0

Tgs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	72,261,575 - 72,300,775 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936496	2,484,864 - 2,524,540 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936496	2,484,700 - 2,524,650 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TGS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	75,937,129 - 75,969,157 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	75,937,489 - 75,969,152 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	82,879,748 - 82,911,839 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TGS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	51,819,132 - 51,868,566 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	51,819,572 - 51,856,172 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	89,932,602 - 89,984,290 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tgs1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624965	66,381 - 114,309 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624965	90,356 - 114,478 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Tgs1
320 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	440
Count of miRNA genes:	223
Interacting mature miRNAs:	289
Transcripts:	ENSRNOT00000010783
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2293666	Bmd38	Bone mineral density QTL 38	4.4		femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	5	8948228	53948228	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
1300117	Hrtrt8	Heart rate QTL 8	3.49		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	3844018	47869213	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	9823266	99753708	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	12789751	113558310	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	729470	86724018	Rat
2312562	Pur18	Proteinuria QTL 18	2.6	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	5	2138965	32656739	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	2282226	69540447	Rat
61462	Niddm10	Non-insulin dependent diabetes mellitus QTL 10	3.9	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	5	5112159	47171491	Rat
1641903	Alcrsp3	Alcohol response QTL 3			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	12689285	57689285	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	90450412	Rat
631827	Alc4	Alcohol consumption QTL 4	3.5		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	5	8187501	18616199	Rat
2313085	Bss59	Bone structure and strength QTL 59	2.9	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	5	3844018	26141981	Rat

D10Chm27

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	5	q12	UniSTS

D5Got321

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	16,540,236 - 16,540,387 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	16,428,719 - 16,428,869	NCBI	Rnor6.0
Rnor_5.0	5	21,209,983 - 21,210,133	UniSTS	Rnor5.0
RGSC_v3.4	5	16,833,754 - 16,833,904	UniSTS	RGSC3.4
Celera	5	15,906,513 - 15,906,663	UniSTS
Cytogenetic Map	5	q12	UniSTS

RH138074

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	16,558,237 - 16,558,374 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	16,446,720 - 16,446,856	NCBI	Rnor6.0
Rnor_5.0	5	21,227,984 - 21,228,120	UniSTS	Rnor5.0
RGSC_v3.4	5	16,851,755 - 16,851,891	UniSTS	RGSC3.4
Celera	5	15,924,156 - 15,924,292	UniSTS
RH 3.4 Map	5	90.3	UniSTS
Cytogenetic Map	5	q12	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001107904	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287525	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000010783 ⟹ ENSRNOP00000010783

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	16,524,874 - 16,558,399 (+)	Ensembl
Rnor_6.0 Ensembl	5	16,413,356 - 16,446,881 (+)	Ensembl

RefSeq Acc Id:

NM_001107904 ⟹ NP_001101374

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	21,322,492 - 21,356,017 (+)	NCBI
mRatBN7.2	5	16,524,874 - 16,558,399 (+)	NCBI
Rnor_6.0	5	16,413,356 - 16,446,881 (+)	NCBI
Rnor_5.0	5	21,194,620 - 21,228,145 (+)	NCBI
RGSC_v3.4	5	16,818,391 - 16,851,916 (+)	RGD
Celera	5	15,891,134 - 15,924,317 (+)	RGD

Sequence:

show sequence

AGCTGCTTCCGGTGGCGCGCCTGGCCGGCTCCGGGCTCGAGCGTCCCCAGGCGCGTTCCGCTCCTCTGCCCGCGCGGGTTACGCCTCTCTGTGTCCAGCAACAGAGCAGAGGCCCGGCCCCGCCGCGG
ACAAAAGAGCGAGCCCGGATAACAAAATGTGTTGCGAGAAGTGGAGCCACGTGGCCGAAATGCTGCTCTTCATTGAAGACCGCGAGGAGGAGTACAAGATCCTTTGCCTCTGCTCCCGAGCATTTGTA
GAGGATCGGAAATTATACAACTTGGGATTAAAAGGCTACTATGTCAAAAGCAGTGGCAATAATGCAGGAGACCGAGTTACAGAAGAGGAGGAAGATGATCATTCCAGTGGCACTACGGAGTCACACAG
CGCAGATGAAGGTGACCTTGACCCCGAGGCCAAACTCATGAGAAGTATGGGCTTACCAGTCCGGTTTGGTAGGATGTCTACGCATGGGAGTTTTGAGGTGTCCATGAATGCAAGAAATAAAGCTAAAG
TGAGGCAGAAGAGGAGAAAGCACCGCAAGCAGTATTTAGATGAAATTGTGCGGGAGGACTGGAGAAATGACTGTGAAGAAGATGACCTTGTAGTCTCCGATGACCCATCCTCAGTTGAACACTGTGAG
AACAACAGCGCATGTGAAATTCAGAGCAAAACAGATGCTGAAGCAGAAAACCTTCCTGTTGAAAATACACTGGCTCCAAAGCTAGAGGTCACAGAGAATTGGGAAAAGTACTGGAATGAATACGGAGA
AGGGCTGTTGTGGCAAAGCTGGCAAGAAAAATATCCAGACCAGACACTGTCTTCTGAACCCTGGAACCTTCCTGATACAAAGGAAGAATGGGAGCAGCACTACAGTCAGCTTTATTGGTATTACTTGG
AGCAGTTCCAGTACTGGGAAGCTCAGGGCTGGACTTTCGTTGCCTCACAAAACTGTGATAAAGATGTTTGCACATCTCATACACAGGTTGACCAGAACGCTGAGAGCAGCCTGAAAGCAGATGGAACG
ACTTTGTCATCTTCACCTAACACAGCTGAGGATGAAAGCCTTGGCTCAAATGACAATGACCACAATGAAATTATTGCTGGGATTAATAAGATAACTCTGAGTGCAGAGGAAGTAGAACAGAGCCAGTT
AGATTCCTCTGAACACTGTGACAAGCCACTCAGTGAAGTCACTGGGAAAGAGTGCCCTGCCTCTGGAGGAAGTGACTCCTGTCATGGAACACCCAAGGAAAGTGACATATCTGAGAACAGAAGCTCAG
ACCAACCAGCTCAAGAGTTGCAGGAATCTTCAGGAACGAATACAAGTAAACATAGACCACACCATAACGGGACTGATGGAAACGAGAGTGAAGATGACCCCCCTGATCATAAGCCTAGCAAAATGAAG
AGAAGCCATGAGTTGGACATTGATGAAAACCCAGATTCGGAAGTTGATGACAATGGTTTCCATCTAGGATTCAAGCATGGCTCAGGACAAAAATATGGTGGAATTCCAAATTTCAGTCGTCGACAGGT
CAGGTATCTAGAGAAGAATGTGAAATACAAGTCAAAGTACCTGGACATGCGCAAGCGGATGACTGTGAAGAACAAGCACATCGTCTTCTCCGAGGAGTCAGGGAAACCCTTTATCAGGAAGAGTAAAG
TACGGAGTAAGGTGGAAAAATTCCTAAAATGGGTTAATGAGCCTGTAGATGAGGAGATATCACAGGAGCCTCTCTCTCACAACAAAATGCAAGACACTTGCACAAGCAGTGACTCTGAGGAACAAGAC
ATGTCCATGGAGAAAACTGATGGTCTGATGGAGACCAGAGATCCAGAACCTGAAAACTGTCAGACCATCTCTTCAGCCAGTGAACTTGAAGCAGAAAAGAGTGAAGGGGGCTCCTTAGTAGCAGCTGT
TCCAGAGAACTGTTCAACTGAAGGAGTAGCAAACTCTCCCCGTGCAGAAGCAGAAGTAGAAATAAAGAAGAAAAAGAAGAAGAAGAAGAAGAACAAGAACAAAAAGATAAATGGCCTACCACCTGAAA
TAGCTTCTGTTCCGGAGCTGGCAAAATACTGGGCCCAGAGATACAGGCTTTTCTCTCGCTTTGATGATGGGATCAAATTGGACAAAGAGGGCTGGTTTTCAGTCACTCCTGAGAAGATTGCTGAGCAC
ATAGCTGGCCGCGTCAGTCAGTCTTTCAACTGTGACATCATAGTAGATGCTTTCTGTGGGGTTGGAGGAAATACCATTCAGTTTGCCTTGACAGGAAAAAGAGTGATTGCCATTGATATCGACCCTGT
TAAAATTGATCTTGCTCGGAATAATGCTGAAGTTTATGGGGTAGCAGATAAAATAGAGTTTATCTGCGGAGATTTCCTGCTCTTGGCTCCATGTTTAAAGGCTGACGTTGTGTTCCTGAGTCCACCGT
GGGGGGGCCCAGATTATGCCACTGCGGAGACCTTTGACATTAGGACCATGATGTCTCCTGATGGCTTTGAAATTTTCAGGCTTTCCCAGAAGATCACTAATAATATTGTTTATTTTCTTCCAAGAAAT
GCTGATGTTGACCAGGTGGCATCGTTGGCTGGGCCTGGAGGACAAGTAGAAATAGAACAGAACTTTCTTAACAACAAGTTAAAGACAATCACTGCATATTTTGGTGACCTGATCAGAAGACCAGCACT
TCGAAGTGCTGAGGCGTGATGCTGTAAAGCACAGAGATCATGAGGAGAGAGGATGGATGTATGGACTGACAGACAGCCTTCGAGTGGGAGACACGAGGAAGATCTTCCTAAGCTCCTTGATACTGTGT
GTGCATGTGATGAAAAGCTGAGCTTTAAAGAATGCTAATGAAGTGGTTTGAGATCTTGGTAATGTTAACTGATCTGTGTTCTGTACTTTAAAACAGCATCAGGACAAGGTGATGGTGGGGGCCTGCAT
CCCAGCCCTTGAAAAAGATCATGAGTTCAAGGCCATGCTGTGCTGCATAACAATTCAAGGCTGGCCTGGGCTACATGCTGTCTTGCCTCAGAATAAACATCATAAAGAGTCTAGGCATATCCCTGTGC
TTACATTAAGTGCATATGTGGTTGTGGGTGTTTTCATTCTTTAACTGTTTTAGTTTATCATCTTTGTGTCTGTGTAAATAATAATTGATTTTTTCAAATGCAAAGAAAAACAAAGCAGTTCTACCTAC
ACATTTAACCCCTATTGAAATAATGTTACCAATTTAATGCTAAAACAAGAAAAGTAAAGTTCCCACCACCTTTTACTCAACTATCTAAAGCTAATCACAGTTAACAATGCTATCCTTTTTAATTTTTT
ATTACATTTTTATTTTGTCTGTATGTGCATGCATGTGTGTGTGTGTAGAGGTCAGAGGACAATTTGTGGGGTTCCCTTCTCTACTTACACCATGTGGGTTCCTGGGAATCAAGTTAAGGTCATCAGGC
TTTATAACCTGAGCCATCCCATTGGTCCCCTGTTAATTCTTCTGGAGAAAAGATTGCATTATAGCAGTATGCTCTGGTGCACTTTCCCATGATGCACTCGCTGTTCGTTCATTGCTGTTCGTAATGGA
TAGTATATAAAATAAATGCTTTTGTGAGAGAAATGTATGTGAGAAAGTGTGTGTGTGTGTGTGTGTGTACACGTATGTACGTACGTGTGTACGTAGGTGTGTACGTAGGTGTGTTCGTGCACTGTACC
CACTATGCCCACAGAGTCCAGGGAAGAGTGTTGGATTCCTTGGAGCTGGAGTTACAGGTGGCTGTGAGCTGCCAAGTGTAGGCACTGAGAAATGCACTTGGGTCTTCTGGAAGCAGAAGTAAGTTCTC
TCTCCAGCCCAAGATGCTTTTTTTAATCAGTATTTTTACATTTCTGTTTTGGTATGGTTTGTTTTTTCAGATAATCTCACATAACCCACACTGGCCTCAACCTTTGTGTGACTGAGAGACTGAGCTCC
TAGGCCCTTCTGGCTCCAGCACTGCACCTGGCTTGTCAGTGTCTGGAAGGCCATTTCAGTTCATACATGTCAATCTACCTCGTGTTCTAAACGGCAGTCTTGTATTTTATCACATGTGCATATAAAAT
AGTTCCCTACTGAGGCACACAGGCTGTTTTTATGGTTTTATCATTACCGATTGTTCCATACTGTCTTTCCTTACAATATTTGCTGTTGAACAAATATTTGTTGGTAAGTTTCTAGCAGTTGGACTGCT
AGGCTTTTGTACATTTCAGTCTTGATAAAAAGACCAAATTGCTTCAATAAAGTTGAACTTGCTTTTAGTCATATTTATCTC

hide sequence

RefSeq Acc Id:

XM_039109760 ⟹ XP_038965688

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	21,322,616 - 21,356,007 (+)	NCBI
mRatBN7.2	5	16,524,864 - 16,558,391 (+)	NCBI

RefSeq Acc Id:

XM_063287525 ⟹ XP_063143595

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	21,325,002 - 21,356,007 (+)	NCBI


Protein RefSeqs	NP_001101374	(Get FASTA)	NCBI Sequence Viewer
	XP_038965688	(Get FASTA)	NCBI Sequence Viewer
	XP_063143595	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM11602	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000010783
	ENSRNOP00000010783.5
GenBank Protein	P85107	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001101374 ⟸ NM_001107904

- UniProtKB:

P85107 (UniProtKB/Swiss-Prot), A6JFK6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MCCEKWSHVAEMLLFIEDREEEYKILCLCSRAFVEDRKLYNLGLKGYYVKSSGNNAGDRVTEEEEDDHSSGTTESHSADEGDLDPEAKLMRSMGLPVRFGRMSTHGSFEVSMNARNKAKVRQKRRKHR
KQYLDEIVREDWRNDCEEDDLVVSDDPSSVEHCENNSACEIQSKTDAEAENLPVENTLAPKLEVTENWEKYWNEYGEGLLWQSWQEKYPDQTLSSEPWNLPDTKEEWEQHYSQLYWYYLEQFQYWEAQ
GWTFVASQNCDKDVCTSHTQVDQNAESSLKADGTTLSSSPNTAEDESLGSNDNDHNEIIAGINKITLSAEEVEQSQLDSSEHCDKPLSEVTGKECPASGGSDSCHGTPKESDISENRSSDQPAQELQE
SSGTNTSKHRPHHNGTDGNESEDDPPDHKPSKMKRSHELDIDENPDSEVDDNGFHLGFKHGSGQKYGGIPNFSRRQVRYLEKNVKYKSKYLDMRKRMTVKNKHIVFSEESGKPFIRKSKVRSKVEKFL
KWVNEPVDEEISQEPLSHNKMQDTCTSSDSEEQDMSMEKTDGLMETRDPEPENCQTISSASELEAEKSEGGSLVAAVPENCSTEGVANSPRAEAEVEIKKKKKKKKKNKNKKINGLPPEIASVPELAK
YWAQRYRLFSRFDDGIKLDKEGWFSVTPEKIAEHIAGRVSQSFNCDIIVDAFCGVGGNTIQFALTGKRVIAIDIDPVKIDLARNNAEVYGVADKIEFICGDFLLLAPCLKADVVFLSPPWGGPDYATA
ETFDIRTMMSPDGFEIFRLSQKITNNIVYFLPRNADVDQVASLAGPGGQVEIEQNFLNNKLKTITAYFGDLIRRPALRSAEA

hide sequence

Ensembl Acc Id:

ENSRNOP00000010783 ⟸ ENSRNOT00000010783

RefSeq Acc Id:	XP_038965688 ⟸ XM_039109760
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063143595 ⟸ XM_063287525
- Peptide Label:	isoform X2

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P85107-F1-model_v2	AlphaFold	P85107	1-850	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13693548

Promoter ID:

EPDNEW_R4073

Type:

initiation region

Name:

Tgs1_1

Description:

trimethylguanosine synthase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	16,413,360 - 16,413,420	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-42126	BioCyc
Ensembl Genes	ENSRNOG00000008156	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000010783	ENTREZGENE
	ENSRNOT00000010783.6	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.150	UniProtKB/Swiss-Prot
InterPro	RNA_cap_Gua-N2-MeTrfase	UniProtKB/Swiss-Prot
	SAM-dependent_MTases	UniProtKB/Swiss-Prot
KEGG Report	rno:312947	UniProtKB/Swiss-Prot
NCBI Gene	312947	ENTREZGENE
PANTHER	S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED	UniProtKB/Swiss-Prot
	TRIMETHYLGUANOSINE SYNTHASE	UniProtKB/Swiss-Prot
Pfam	Methyltransf_15	UniProtKB/Swiss-Prot
PhenoGen	Tgs1	PhenoGen
RatGTEx	ENSRNOG00000008156	RatGTEx
Superfamily-SCOP	SSF53335	UniProtKB/Swiss-Prot
UniProt	A6JFK6	ENTREZGENE, UniProtKB/TrEMBL
	P85107	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-10-16	Tgs1	trimethylguanosine synthase 1	Tgs1	trimethylguanosine synthase homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-04	Tgs1	trimethylguanosine synthase homolog (S. cerevisiae)	Ncoa6ip_predicted	nuclear receptor coactivator 6 interacting protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Ncoa6ip_predicted	nuclear receptor coactivator 6 interacting protein (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)