Ikbkg (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Ikbkg (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma) Chinchilla lanigera
Analyze
Symbol: Ikbkg
Name: inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
RGD ID: 8776917
Description: ENCODES a protein that exhibits identical protein binding (ortholog); K63-linked polyubiquitin modification-dependent protein binding (ortholog); linear polyubiquitin binding (ortholog); INVOLVED IN anoikis (ortholog); B cell homeostasis (ortholog); canonical NF-kappaB signal transduction (ortholog); PARTICIPATES IN FasL mediated signaling pathway; interleukin-1 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH acute myocardial infarction (ortholog); adrenoleukodystrophy (ortholog); autistic disorder (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); IkappaB kinase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of nuclear factor kappa B kinase subunit gamma; NF-kappa-B essential modulator
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555801,053,823 - 1,069,802 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555801,053,823 - 1,069,802 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ikbkg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555801,053,823 - 1,069,802 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555801,053,823 - 1,069,802 (+)NCBIChiLan1.0ChiLan1.0
IKBKG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,541,238 - 154,565,046 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX154,541,199 - 154,565,046 (+)EnsemblGRCh38hg38GRCh38
GRCh37X153,769,453 - 153,793,261 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,423,653 - 153,446,455 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X153,339,765 - 153,356,964NCBI
CeleraX153,931,508 - 153,953,200 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX142,346,885 - 142,356,952 (+)NCBIHuRef
CHM1_1X153,682,228 - 153,705,030 (+)NCBICHM1_1
T2T-CHM13v2.0X152,777,621 - 152,801,428 (+)NCBIT2T-CHM13v2.0
Ikbkg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X73,436,883 - 73,498,013 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX73,436,896 - 73,497,460 (+)EnsemblGRCm39 Ensembl
GRCm38X74,393,233 - 74,456,792 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX74,393,290 - 74,453,854 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X71,638,630 - 71,699,117 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X70,682,424 - 70,704,240 (+)NCBIMGSCv36mm8
CeleraX65,647,484 - 65,706,592 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX38.0NCBI
Ikbkg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X157,358,279 - 157,397,563 (+)NCBIGRCr8
mRatBN7.2X152,216,485 - 152,241,476 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX152,216,596 - 152,239,499 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX154,366,048 - 154,379,411 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X157,928,859 - 157,942,222 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X155,601,075 - 155,614,438 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X156,254,187 - 156,280,046 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX156,257,173 - 156,270,748 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01151,994,689 - 152,019,874 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,386,558 - 160,420,190 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X160,483,372 - 160,496,394 (+)NCBI
Celera1135,659,513 - 135,672,876 (-)NCBICelera
Cytogenetic MapXq37NCBI
IKBKG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X154,521,470 - 154,539,144 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X154,524,964 - 154,546,311 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X143,988,720 - 144,010,078 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X153,869,352 - 153,876,677 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,854,493 - 153,876,092 (+)Ensemblpanpan1.1panPan2
IKBKG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,232,052 - 122,253,499 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX122,235,878 - 122,250,562 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X125,373,537 - 125,395,176 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX125,373,743 - 125,395,172 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X121,142,500 - 121,164,137 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X123,657,571 - 123,679,200 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X123,419,351 - 123,440,993 (+)NCBIUU_Cfam_GSD_1.0
Ikbkg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,519,768 - 119,569,193 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368091,257,654 - 1,301,813 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049368091,280,254 - 1,306,964 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IKBKG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX125,036,508 - 125,056,453 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X125,035,575 - 125,056,445 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X143,478,840 - 143,498,934 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IKBKG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X128,781,975 - 128,816,039 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX128,787,785 - 128,806,083 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606566,774,279 - 66,797,151 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ikbkg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624946996,814 - 1,013,379 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624946997,571 - 1,015,748 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005337   ⟹   ENSCLAP00000005241
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555801,053,823 - 1,069,802 (+)Ensembl
RefSeq Acc Id: XM_005414210   ⟹   XP_005414267
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555801,053,832 - 1,069,802 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005414211   ⟹   XP_005414268
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555801,053,828 - 1,069,802 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005414213   ⟹   XP_005414270
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555801,053,828 - 1,069,802 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005414214   ⟹   XP_005414271
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555801,053,823 - 1,069,802 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013509705   ⟹   XP_013365159
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555801,058,241 - 1,069,802 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013509706   ⟹   XP_013365160
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555801,058,922 - 1,069,802 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005414271   ⟸   XM_005414214
- Peptide Label: isoform X4
- UniProtKB: A0A8C2UTV6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005414270   ⟸   XM_005414213
- Peptide Label: isoform X3
- UniProtKB: A0A8C2UTV6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005414268   ⟸   XM_005414211
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UTV6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005414267   ⟸   XM_005414210
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013365159   ⟸   XM_013509705
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_013365160   ⟸   XM_013509706
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSCLAP00000005241   ⟸   ENSCLAT00000005337
Protein Domains
CCHC NOA-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003721 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005337 ENTREZGENE
  ENSCLAT00000005337.1 UniProtKB/TrEMBL
Gene3D-CATH L1 transposable element, trimerization domain UniProtKB/TrEMBL
  Nemo cc2-lz domain - 1d5 darpin complex UniProtKB/TrEMBL
InterPro CC2-LZ_dom UniProtKB/TrEMBL
  NEMO_N UniProtKB/TrEMBL
  NEMO_ZF UniProtKB/TrEMBL
NCBI Gene Ikbkg ENTREZGENE
PANTHER NF-KAPPA-B ESSENTIAL MODULATOR UniProtKB/TrEMBL
  NF-KAPPA-B ESSENTIAL MODULATOR UniProtKB/TrEMBL
Pfam CC2-LZ UniProtKB/TrEMBL
  NEMO UniProtKB/TrEMBL
  zf_C2H2_10 UniProtKB/TrEMBL
PROSITE ZF_CCHC_NOA UniProtKB/TrEMBL
UniProt A0A8C2UTV6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 Ikbkg  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma    inhibitor of nuclear factor kappa B kinase subunit gamma  Symbol and/or name change 5135510 APPROVED
2017-01-17 Ikbkg  inhibitor of nuclear factor kappa B kinase subunit gamma    inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma  Symbol and/or name change 5135510 APPROVED