Ikbkg (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma) - Rat Genome Database

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Gene: Ikbkg (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma) Heterocephalus glaber
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Symbol: Ikbkg
Name: inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
RGD ID: 18905492
Description: ENCODES a protein that exhibits identical protein binding (ortholog); linear polyubiquitin binding (ortholog); peroxisome proliferator activated receptor binding (ortholog); INVOLVED IN anoikis (ortholog); B cell homeostasis (ortholog); canonical NF-kappaB signal transduction (ortholog); PARTICIPATES IN FasL mediated signaling pathway; interleukin-1 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH acute myocardial infarction (ortholog); adrenoleukodystrophy (ortholog); autistic disorder (ortholog); FOUND IN cytosol (ortholog); IkappaB kinase complex (ortholog); mitotic spindle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of nuclear factor kappa B kinase subunit gamma; NF-kappa-B essential modulator
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624946996,814 - 1,013,379 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624946997,571 - 1,015,748 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ikbkg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624946996,814 - 1,013,379 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624946997,571 - 1,015,748 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
IKBKG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,541,238 - 154,565,046 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX154,541,199 - 154,565,046 (+)EnsemblGRCh38hg38GRCh38
GRCh37X153,769,453 - 153,793,261 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,423,653 - 153,446,455 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X153,339,765 - 153,356,964NCBI
CeleraX153,931,508 - 153,953,200 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX142,346,885 - 142,356,952 (+)NCBIHuRef
CHM1_1X153,682,228 - 153,705,030 (+)NCBICHM1_1
T2T-CHM13v2.0X152,777,621 - 152,801,428 (+)NCBIT2T-CHM13v2.0
Ikbkg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X73,436,883 - 73,498,013 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX73,436,896 - 73,497,460 (+)EnsemblGRCm39 Ensembl
GRCm38X74,393,233 - 74,456,792 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX74,393,290 - 74,453,854 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X71,638,630 - 71,699,117 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X70,682,424 - 70,704,240 (+)NCBIMGSCv36mm8
CeleraX65,647,484 - 65,706,592 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX38.0NCBI
Ikbkg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X157,358,279 - 157,397,563 (+)NCBIGRCr8
mRatBN7.2X152,216,485 - 152,241,476 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX152,216,596 - 152,239,499 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX154,366,048 - 154,379,411 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X157,928,859 - 157,942,222 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X155,601,075 - 155,614,438 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X156,254,187 - 156,280,046 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX156,257,173 - 156,270,748 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01151,994,689 - 152,019,874 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,386,558 - 160,420,190 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X160,483,372 - 160,496,394 (+)NCBI
Celera1135,659,513 - 135,672,876 (-)NCBICelera
Cytogenetic MapXq37NCBI
Ikbkg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555801,053,823 - 1,069,802 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555801,053,823 - 1,069,802 (+)NCBIChiLan1.0ChiLan1.0
IKBKG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X154,521,470 - 154,539,144 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X154,524,964 - 154,546,311 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X143,988,720 - 144,010,078 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X153,869,352 - 153,876,677 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,854,493 - 153,876,092 (+)Ensemblpanpan1.1panPan2
IKBKG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,232,052 - 122,253,499 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX122,235,878 - 122,250,562 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X125,373,537 - 125,395,176 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX125,373,743 - 125,395,172 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X121,142,500 - 121,164,137 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X123,657,571 - 123,679,200 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X123,419,351 - 123,440,993 (+)NCBIUU_Cfam_GSD_1.0
Ikbkg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,519,768 - 119,569,193 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368091,257,654 - 1,301,813 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049368091,280,254 - 1,306,964 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IKBKG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX125,036,508 - 125,056,453 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X125,035,575 - 125,056,445 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X143,478,840 - 143,498,934 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IKBKG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X128,781,975 - 128,816,039 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX128,787,785 - 128,806,083 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606566,774,279 - 66,797,151 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000001942   ⟹   ENSHGLP00000001896
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624946996,814 - 1,013,379 (+)Ensembl
RefSeq Acc Id: XM_004875020   ⟹   XP_004875077
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624946997,571 - 1,015,748 (+)NCBI
RefSeq Acc Id: XM_004875021   ⟹   XP_004875078
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249461,001,886 - 1,015,748 (+)NCBI
RefSeq Acc Id: XM_021252341   ⟹   XP_021108000
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249461,001,884 - 1,015,748 (+)NCBI
RefSeq Acc Id: XM_021252342   ⟹   XP_021108001
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249461,005,253 - 1,015,748 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004875077 (Get FASTA)   NCBI Sequence Viewer  
  XP_004875078 (Get FASTA)   NCBI Sequence Viewer  
  XP_021108000 (Get FASTA)   NCBI Sequence Viewer  
  XP_021108001 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004875077   ⟸   XM_004875020
- Peptide Label: isoform X1
- UniProtKB: G5BFL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108000   ⟸   XM_021252341
- Peptide Label: isoform X2
- UniProtKB: G5BFL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004875078   ⟸   XM_004875021
- Peptide Label: isoform X1
- UniProtKB: G5BFL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108001   ⟸   XM_021252342
- Peptide Label: isoform X3
- UniProtKB: G5BFL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000001896   ⟸   ENSHGLT00000001942


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001447 Ensembl
Gene3D-CATH L1 transposable element, trimerization domain UniProtKB/TrEMBL
  Nemo cc2-lz domain - 1d5 darpin complex UniProtKB/TrEMBL
InterPro CC2-LZ_dom UniProtKB/TrEMBL
  NEMO_N UniProtKB/TrEMBL
  NEMO_ZF UniProtKB/TrEMBL
NCBI Gene Ikbkg ENTREZGENE
PANTHER NF-KAPPA-B ESSENTIAL MODULATOR UniProtKB/TrEMBL
  NF-KAPPA-B ESSENTIAL MODULATOR UniProtKB/TrEMBL
Pfam CC2-LZ UniProtKB/TrEMBL
  NEMO UniProtKB/TrEMBL
  zf_C2H2_10 UniProtKB/TrEMBL
PROSITE ZF_CCHC_NOA UniProtKB/TrEMBL
UniProt G5BFL6 ENTREZGENE, UniProtKB/TrEMBL