Muc5ac (mucin 5AC, oligomeric mucus/gel-forming)

Gene: Muc5ac (mucin 5AC, oligomeric mucus/gel-forming) Heterocephalus glaber

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Symbol:

Muc5ac

Name:

mucin 5AC, oligomeric mucus/gel-forming

RGD ID:

18907319

Description:

INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular response to retinoic acid (ortholog); ASSOCIATED WITH allergic rhinitis (ortholog); angle-closure glaucoma (ortholog); asthma (ortholog); FOUND IN extracellular space (ortholog); mucus layer (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Mucin-5AC

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624766	21,439,023 - 21,461,108 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

allergic rhinitis (ISO)

angle-closure glaucoma (ISO)

asthma (ISO)

biliary tract benign neoplasm (ISO)

cholangiocarcinoma (ISO)

chronic obstructive pulmonary disease (ISO)

common bile duct neoplasm (ISO)

corneal ulcer (ISO)

cystic fibrosis (ISO)

cystitis (ISO)

delta beta-thalassemia (ISO)

developmental and epileptic encephalopathy (ISO)

Diffuse Panbronchiolitis (ISO)

dry eye syndrome (ISO)

early infantile epileptic encephalopathy (ISO)

Gallbladder Neoplasms (ISO)

gastric ulcer (ISO)

glaucoma (ISO)

immunodeficiency 39 (ISO)

keratoconjunctivitis (ISO)

keratoconjunctivitis sicca (ISO)

keratoconus (ISO)

lung adenocarcinoma (ISO)

Lymphatic Metastasis (ISO)

Metaplasia (ISO)

mucinous adenocarcinoma (ISO)

Nasal Polyps (ISO)

Nematode Infections (ISO)

Neoplasm Metastasis (ISO)

neuronal ceroid lipofuscinosis (ISO)

otitis media (ISO)

Otitis Media with Effusion (ISO)

pancreatic cancer (ISO)

pancreatic ductal carcinoma (ISO)

Picornaviridae Infections (ISO)

pulmonary fibrosis (ISO)

respiratory syncytial virus infectious disease (ISO)

rhinitis (ISO)

Rhinosinusitis (ISO)

Segawa Syndrome, Autosomal Recessive (ISO)

Sjogren's syndrome (ISO)

squamous cell carcinoma (ISO)

stomach disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to epidermal growth factor stimulus (ISO)

cellular response to glucocorticoid stimulus (ISO)

cellular response to retinoic acid (ISO)

epithelial cell differentiation (ISO)

maintenance of lens transparency (ISO)

response to lipopolysaccharide (ISO)

response to ozone (ISO)

response to sulfur dioxide (ISO)

response to vitamin A (ISO)

Cellular Component

extracellular space (ISO)

mucus layer (ISO)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:21993625	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Muc5ac
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624766	21,439,023 - 21,461,108 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

MUC5AC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	1,157,953 - 1,201,138 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	1,157,953 - 1,201,138 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	1,151,580 - 1,222,364 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	1,169,363 - 1,178,940 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	1,141,594 - 1,152,361	NCBI
Celera	11	1,216,270 - 1,325,135 (+)	NCBI		Celera
Cytogenetic Map	11	p15.5	NCBI
HuRef	11	979,261 - 1,006,024 (+)	NCBI		HuRef
CHM1_1	11	1,141,384 - 1,221,279 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	1,229,366 - 1,272,380 (+)	NCBI		T2T-CHM13v2.0

Muc5ac
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	141,342,695 - 141,372,964 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	141,342,709 - 141,372,968 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	141,788,958 - 141,819,227 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	141,788,972 - 141,819,231 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	148,974,916 - 149,005,040 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	148,974,916 - 149,005,040 (+)	NCBI		MGSCv36	mm8
Celera	7	141,544,129 - 141,573,772 (+)	NCBI		Celera
Cytogenetic Map	7	F5	NCBI
cM Map	7	87.23	NCBI

Muc5ac
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	206,293,717 - 206,326,006 (+)	NCBI		GRCr8
mRatBN7.2	1	196,864,336 - 196,896,475 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	196,864,336 - 196,896,475 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	1	214,725,482 - 214,756,653 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	214,727,416 - 214,741,252 (+)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	221,642,507 - 221,671,770 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	1	194,493,496 - 194,524,940 (+)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI

Muc5ac
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955476	11,061,405 - 11,084,294 (-)	NCBI	ChiLan1.0	ChiLan1.0

MUC5AC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	3,571,337 - 3,614,623 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	2,783,098 - 2,826,292 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	1,191,223 - 1,234,373 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	1,225,362 - 1,272,411 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

MUC5AC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	45,471,232 - 45,498,961 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	44,080,267 - 44,110,233 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	46,149,914 - 46,180,208 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	18	45,598,266 - 45,628,540 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	45,178,618 - 45,208,933 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	45,916,410 - 45,946,691 (+)	NCBI		UU_Cfam_GSD_1.0

Muc5ac
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	875,887 - 905,133 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936816	129,926 - 159,396 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MUC5AC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	2	757,897 - 790,321 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

MUC5AC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	981,515 - 1,018,242 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	98,106,473 - 98,148,026 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021263738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AHKG01046961	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AHKG01046962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AHKG01046963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JH173516	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JH173915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_021263738 ⟹ XP_021119397

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624766	21,439,023 - 21,461,108 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_021119397	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EHB17063	(Get FASTA)	NCBI Sequence Viewer
	EHB17873	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021119397 ⟸ XM_021263738

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Muc5ac	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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