PGF (placental growth factor) - Rat Genome Database

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Gene: PGF (placental growth factor) Chlorocebus sabaeus
Analyze
Symbol: PGF
Name: placental growth factor
RGD ID: 18479797
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN animal organ regeneration (ortholog); branching involved in ureteric bud morphogenesis (ortholog); cellular response to hormone stimulus (ortholog); PARTICIPATES IN vascular endothelial growth factor signaling pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); ankylosing spondylitis (ortholog); asthma (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: placenta growth factor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12452,160,904 - 52,174,493 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2452,161,787 - 52,173,989 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605340,391,564 - 40,405,145 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PGF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12452,160,904 - 52,174,493 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2452,161,787 - 52,173,989 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605340,391,564 - 40,405,145 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PGF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381474,941,830 - 74,955,764 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1474,941,834 - 74,955,626 (-)EnsemblGRCh38hg38GRCh38
GRCh371475,408,533 - 75,422,467 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361474,478,290 - 74,492,044 (-)NCBINCBI36Build 36hg18NCBI36
Build 341474,478,292 - 74,492,044NCBI
Celera1455,446,919 - 55,460,674 (-)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1455,576,546 - 55,590,481 (-)NCBIHuRef
CHM1_11475,347,700 - 75,361,635 (-)NCBICHM1_1
T2T-CHM13v2.01469,150,944 - 69,164,879 (-)NCBIT2T-CHM13v2.0
Pgf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391285,213,413 - 85,224,087 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1285,213,409 - 85,224,564 (-)EnsemblGRCm39 Ensembl
GRCm381285,166,637 - 85,177,785 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1285,166,635 - 85,177,790 (-)EnsemblGRCm38mm10GRCm38
MGSCv371286,507,591 - 86,518,235 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361286,055,744 - 86,066,388 (-)NCBIMGSCv36mm8
Celera1286,623,655 - 86,634,299 (-)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1239.58NCBI
Pgf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86110,547,165 - 110,557,747 (-)NCBIGRCr8
mRatBN7.26104,816,102 - 104,826,685 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6104,816,104 - 104,826,685 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6104,985,728 - 104,996,309 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06105,284,901 - 105,295,482 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06104,654,265 - 104,664,846 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06108,994,016 - 109,004,598 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6108,994,018 - 109,004,598 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06116,552,660 - 116,563,242 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46109,215,540 - 109,226,122 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16109,218,997 - 109,229,578 (-)NCBI
Celera6102,639,061 - 102,649,643 (-)NCBICelera
RH 3.4 Map6731.99RGD
Cytogenetic Map6q31NCBI
Pgf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955523616,154 - 627,713 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955523616,196 - 627,055 (+)NCBIChiLan1.0ChiLan1.0
PGF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21576,024,811 - 76,038,594 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11475,241,311 - 75,255,228 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01455,494,152 - 55,508,066 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11474,338,976 - 74,352,964 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1474,338,976 - 74,352,964 (-)Ensemblpanpan1.1panPan2
PGF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1848,059,554 - 48,110,534 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl848,059,552 - 48,075,170 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha847,743,752 - 47,795,118 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0848,287,229 - 48,338,603 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1847,958,057 - 48,009,418 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0847,979,365 - 48,030,910 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0848,377,990 - 48,429,367 (-)NCBIUU_Cfam_GSD_1.0
Pgf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864027,957,791 - 27,970,740 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364884,098,225 - 4,111,142 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364884,098,187 - 4,111,108 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl798,148,994 - 98,162,741 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1798,149,510 - 98,162,784 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27103,993,598 - 104,006,849 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pgf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473426,751,530 - 26,764,242 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473426,751,986 - 26,764,154 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 7 7
Low 29 15 51
Below cutoff 5 2

Sequence


RefSeq Acc Id: ENSCSAT00000010289   ⟹   ENSCSAP00000008384
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2452,161,787 - 52,173,989 (-)Ensembl
RefSeq Acc Id: XM_007987292   ⟹   XP_007985483
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12452,160,904 - 52,174,493 (-)NCBI
Vero_WHO_p1.0NW_02366605340,391,564 - 40,405,145 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007987293   ⟹   XP_007985484
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12452,160,904 - 52,174,493 (-)NCBI
Vero_WHO_p1.0NW_02366605340,391,564 - 40,405,145 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037984263   ⟹   XP_037840191
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605340,391,564 - 40,405,145 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007985483 (Get FASTA)   NCBI Sequence Viewer  
  XP_007985484 (Get FASTA)   NCBI Sequence Viewer  
  XP_037840191 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008384
  ENSCSAP00000008384.1
RefSeq Acc Id: XP_007985484   ⟸   XM_007987293
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007985483   ⟸   XM_007987292
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RIE5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000008384   ⟸   ENSCSAT00000010289
RefSeq Acc Id: XP_037840191   ⟸   XM_037984263
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012223 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010289.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  PD_growth_factor_CS UniProtKB/TrEMBL
  PDGF/VEGF_dom UniProtKB/TrEMBL
KEGG Report csab:103229341 UniProtKB/TrEMBL
NCBI Gene PGF ENTREZGENE
PANTHER PLACENTA GROWTH FACTOR UniProtKB/TrEMBL
  VASCULAR ENDOTHELIAL GROWTH FACTOR UniProtKB/TrEMBL
Pfam PDGF UniProtKB/TrEMBL
PROSITE PDGF_1 UniProtKB/TrEMBL
  PDGF_2 UniProtKB/TrEMBL
SMART PDGF UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A0D9RIE5 ENTREZGENE, UniProtKB/TrEMBL