ABCG2A (ATP binding cassette subfamily G member 2A)

Gene: ABCG2A (ATP binding cassette subfamily G member 2A) Sus scrofa

Analyze

Symbol:

ABCG2A (Ensembl: ABCG2)

Name:

ATP binding cassette subfamily G member 2A (Ensembl:ATP-binding cassette, sub-family G (WHITE), member 2)

RGD ID:

13956643

Description:

ENCODES a protein that exhibits amide transmembrane transporter activity (ortholog); ATPase-coupled transmembrane transporter activity (ortholog); biotin transmembrane transporter activity (ortholog); INVOLVED IN biotin transport (ortholog); cellular detoxification (ortholog); cellular response to dexamethasone stimulus (ortholog); PARTICIPATES IN docetaxel pharmacodynamics pathway; doxorubicin pharmacokinetics pathway; erlotinib pharmacodynamics pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute megakaryocytic leukemia (ortholog); acute myeloid leukemia (ortholog); FOUND IN apical plasma membrane (ortholog); brush border membrane (ortholog); external side of apical plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

ABCG2; ATP-binding cassette sub-family G member 2; ATP-binding cassette, sub-family G (WHITE), member 2; BMDP; brain multidrug resistance protein; broad substrate specificity ATP-binding cassette transporter ABCG2; urate exporter

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	130,889,684 - 130,945,393 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	130,853,414 - 130,945,388 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	140,193,291 - 140,228,765 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute lymphoblastic leukemia (ISO)

acute megakaryocytic leukemia (ISO)

acute myeloid leukemia (ISO)

adenoma (ISO)

autism spectrum disorder (ISO)

autosomal dominant polycystic kidney disease (ISO)

B-Cell Chronic Lymphocytic Leukemia (ISO)

B-cell lymphoma (ISO)

breast carcinoma (ISO)

Breast Neoplasms (ISO)

cardiomyopathy (ISO)

chronic myeloid leukemia (ISO)

Colorectal Neoplasms (ISO)

congestive heart failure (ISO)

diabetes mellitus (ISO)

diarrhea (ISO)

diffuse large B-cell lymphoma (ISO)

erythropoietic protoporphyria (ISO)

Experimental Arthritis (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Mammary Neoplasms (ISO)

genetic disease (ISO)

gout (ISO)

head and neck squamous cell carcinoma (ISO)

hereditary breast ovarian cancer syndrome (ISO)

hyperuricemia (ISO)

Liver Injury (ISO)

multiple myeloma (ISO)

nervous system disease (ISO)

Ovarian Neoplasms (ISO)

primary biliary cholangitis (ISO)

renal cell carcinoma (ISO)

Reperfusion Injury (ISO)

rheumatoid arthritis (ISO)

secondary hyperparathyroidism (ISO)

status epilepticus (ISO)

T-cell acute lymphoblastic leukemia (ISO)

toxic encephalopathy (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biotin transport (ISS)

cellular detoxification (ISO)

cellular response to dexamethasone stimulus (ISO)

cellular response to estradiol stimulus (ISO)

embryonic process involved in female pregnancy (ISO)

export across plasma membrane (ISO)

glucuronoside metabolic process (ISO)

lipid transport (IEA)

negative regulation of intestinal absorption (ISO)

organic anion transport (ISO)

protein-containing complex assembly (ISO)

renal urate salt excretion (ISO,ISS)

response to 2,3,7,8-tetrachlorodibenzodioxine (ISO)

response to alcohol (ISO)

response to folic acid (ISO)

response to insulin (ISO)

response to iron ion (ISO)

response to lipopolysaccharide (ISO)

riboflavin transport (ISS)

transepithelial transport (ISO)

transmembrane transport (IBA,IEA,ISO,ISS)

urate metabolic process (ISO)

urate transport (IEA,ISO)

xenobiotic detoxification by transmembrane export across the plasma membrane (ISO)

xenobiotic transport (IEA)

xenobiotic transport across blood-brain barrier (ISO)

Cellular Component

apical plasma membrane (IEA,ISO,ISS)

brush border membrane (ISS)

external side of apical plasma membrane (ISO)

membrane (IEA)

membrane raft (ISS)

mitochondrial membrane (IEA)

mitochondrion (IEA)

nucleoplasm (ISO)

plasma membrane (IBA,IEA)

Molecular Function

ABC-type transporter activity (IEA)

ABC-type xenobiotic transporter activity (IEA)

amide transmembrane transporter activity (ISO)

ATP binding (IEA)

ATP hydrolysis activity (IEA)

ATPase-coupled transmembrane transporter activity (IBA,IEA,ISS)

biotin transmembrane transporter activity (ISS)

cytoskeletal protein binding (ISO)

efflux transmembrane transporter activity (IBA,IEA,ISS)

identical protein binding (ISO)

organic anion transmembrane transporter activity (ISO)

protein binding (ISO)

protein homodimerization activity (ISO)

riboflavin transmembrane transporter activity (IBA,IEA,ISS)

urate transmembrane transporter activity (ISS)

xenobiotic transmembrane transporter activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

docetaxel pharmacodynamics pathway (ISO)

doxorubicin pharmacokinetics pathway (ISO)

erlotinib pharmacodynamics pathway (ISO)

gefitinib pharmacokinetics pathway (ISO)

hypoxia inducible factor pathway (ISO)

irinotecan pharmacodynamics pathway (ISO)

irinotecan pharmacokinetics pathway (ISO)

lamivudine pharmacokinetics pathway (ISO)

mycophenolic acid pharmacokinetics pathway (ISO)

paracetamol pharmacokinetics pathway (ISO)

statin pharmacokinetics pathway (ISO)

tyrosinemia type III pathway (ISO)

References

Additional References at PubMed

PMID:12054514	PMID:14681463	PMID:17145712	PMID:22301074	PMID:26661076	PMID:30032202

Genomics

Comparative Map Data

ABCG2A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	130,889,684 - 130,945,393 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	130,853,414 - 130,945,388 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	140,193,291 - 140,228,765 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ABCG2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	88,090,264 - 88,231,626 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	88,090,150 - 88,231,628 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	89,011,416 - 89,152,778 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	89,230,440 - 89,299,035 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	89,370,018 - 89,436,901	NCBI
Celera	4	86,303,350 - 86,371,627 (-)	NCBI		Celera
Cytogenetic Map	4	q22.1	NCBI
HuRef	4	84,757,887 - 84,903,974 (-)	NCBI		HuRef
CHM1_1	4	88,988,243 - 89,128,985 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	91,416,761 - 91,562,592 (-)	NCBI		T2T-CHM13v2.0

Abcg2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	58,561,476 - 58,669,436 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	58,561,508 - 58,672,661 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	58,584,491 - 58,692,451 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	58,584,523 - 58,695,676 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	58,546,666 - 58,642,445 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	58,526,250 - 58,622,029 (+)	NCBI		MGSCv36	mm8
Celera	6	60,752,972 - 60,848,739 (+)	NCBI		Celera
Cytogenetic Map	6	B3	NCBI
cM Map	6	27.82	NCBI

Abcg2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	89,006,056 - 89,132,915 (+)	NCBI		GRCr8
mRatBN7.2	4	87,676,241 - 87,802,757 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	87,745,319 - 87,802,409 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	92,961,189 - 93,018,372 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	88,736,572 - 88,793,756 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	87,105,627 - 87,162,776 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	88,765,441 - 88,890,268 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	88,832,178 - 88,890,621 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	153,587,206 - 153,712,481 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	87,502,584 - 87,560,017 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	87,747,008 - 87,804,442 (+)	NCBI
Celera	4	82,507,731 - 82,564,802 (+)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

Abcg2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955474	12,365,903 - 12,408,715 (+)	NCBI	ChiLan1.0	ChiLan1.0

ABCG2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	86,093,103 - 86,236,613 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	86,353,103 - 86,499,020 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	80,379,108 - 80,446,641 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	91,101,321 - 91,170,418 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	91,101,321 - 91,170,157 (-)	Ensembl	panpan1.1		panPan2

ABCG2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	11,443,778 - 11,517,674 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	11,443,780 - 11,517,674 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	30,372,283 - 30,510,869 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	11,496,580 - 11,635,323 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	11,496,586 - 11,573,345 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	11,580,165 - 11,719,079 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	11,406,011 - 11,544,317 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	28,508,945 - 28,549,001 (+)	NCBI		UU_Cfam_GSD_1.0
UU_Cfam_GSD_1.0	32	28,373,259 - 28,501,671 (+)	NCBI		UU_Cfam_GSD_1.0

ABCG2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	36,458,110 - 36,599,753 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666037	15,206,025 - 15,348,744 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in ABCG2A
2709 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium
Low	10	3	3	5	2	23	2	3	1
Below cutoff		1							2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_214010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ420927	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK239126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK393001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK396174	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK396738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK397814	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU928800	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01023151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000036315 ⟹ ENSSSCP00000028287

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	8	130,905,179 - 130,945,333 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000036626 ⟹ ENSSSCP00000028560

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	8	130,889,684 - 130,945,393 (+)	Ensembl

RefSeq Acc Id:

NM_214010 ⟹ NP_999175

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	8	130,853,414 - 130,945,388 (+)	NCBI

Sequence:

show sequence

ACGCGGGGGAGCATAAGAGTTCCTGAGATTGGAGCCCTTGGTTGAACTGAACCGTTATTAAGCT
GAAAAGGCAGAAACACTCCAGATGTCCTCCAATAGTTACCAAGTTTCAATCCCGATGTCAAAAA
GGAACACCAATGGCCTGCCGGGGTCCAGCTCCAATGAGCTGAAGACGTCTGCTGGGGGAGCTGT
GTTAAGCTTTCATGACATCTGCTATCGAGTGAAAGTGAAGAGTGGCTTTCTTTTTTGTCGGAAA
ACGGTTGAGAAGGAAATACTGACGAACATCAATGGGATCATGAAACCTGGCCTCAATGCCATTC
TGGGACCCACAGGTGGAGGCAAATCTTCGTTGTTAGATGTCTTAGCTGCAAGGAAAGATCCGCA
TGGATTATCTGGAGATGTTTTGATCAATGGAGCACCTCGACCTGCCAATTTTAAATGTAACTCA
GGTTACGTGGTACAGGATGACGTCGTGATGGGAACGCTGACAGTGAGAGAAAACTTACAGTTCT
CGGCAGCTCTTCGGCTTCCGACCACCATGACAAATCATGAAAAAAATGAGCGGATTAACATGGT
CATTCAAGAGTTGGGTCTGGATAAAGTGGCCGATTCCAAGGTGGGAACCCAGTTTATCCGTGGT
GTGTCTGGAGGAGAAAGAAAACGGACTAGTATTGCAATGGAGCTTATTACTGACCCGTCTATCT
TGTTCCTGGATGAGCCCACGACTGGCTTAGACTCCAGCACAGCAAATGCTGTCCTTTTGCTCCT
GAAGAGGATGTCTAAACAAGGACGGACCATCATCTTCTCCATTCATCAGCCTCGTTACTCCATC
TTTAAGTTGTTTGATAGCCTCACCTTGTTGGCCTCAGGAAGACTCATGTTCCATGGACCTGCTC
GGGAGGCCTTGGGATACTTTGCCTCCATCGGTTACAACTGTGAGCCCTACAACAACCCCGCAGA
CTTCTTCCTGGACGTCATTAACGGCGACTCCTCCGCTGTGGTGTTAAGCAGAGCGGACAGAGAC
GAGGGAGCCCAAGAGCCCGAAGAGCCTCCCGAGAAAGATACTCCCCTCATAGACAAACTTGCTG
CGTTTTATACCAACTCCTCCTTCTTCAAGGACACGAAGGTTGAGTTAGATCAGTTCTCAGGGGG
TCGGAAGAAGAAGAAGAGCTCGGTGTACAAGGAGGTCACCTACACCACCTCCTTCTGTCATCAG
CTCCGATGGATTTCCAGGCGTTCCTTCAAAAACTTACTGGGTAATCCCCAGGCGTCCGTAGCCC
AGATAATTGTGACGATCATCCTGGGCCTGGTTATAGGTGCCATTTTCTATGATCTGAAAAATGA
TCCCTCAGGAATCCAGAACAGAGCCGGAGTGCTCTTCTTCCTGACAACCAACCAGTGTTTCAGC
AGCGTCTCGGCCGTGGAGCTCCTTGTGGTGGAGAAGAAACTCTTTATACATGAATATATCAGTG
GATACTACAGAGTGTCATCTTATTTCTTCGGAAAACTGTTATCGGATTTACTACCCATGAGGAT
GTTACCAAGCATTATCTTTACTTGTATAACGTACTTCTTGTTAGGACTGAAGCCCGCGGTGGGG
TCCTTCTTCATCATGATGTTTACCCTGATGATGGTGGCGTACTCAGCCAGTTCCATGGCCCTGG
CCATAGCCGCCGGTCAGAGCGTGGTCTCCGTGGCAACACTTCTCATGACCATCTCGTTTGTGTT
CATGATGATCTTTTCGGGGCTGTTGGTGAATCTCAAAACGGTCGTGCCTTGGCTCTCGTGGTTA
CAGTACTTCAGCATTCCTCGATACGGCTTTTCGGCTTTGCAGTATAATGAGTTTTTGGGACAAA
ACTTCTGCCCGGGACTCAACGTCACAACAAACAATACCTGTAGCTTCGCAATATGTACTGGCGC
CGAGTATTTGGAAAACCAGGGCATCAGTCTCTCCGCTTGGGGCCTGTGGCAGAATCACGTGGCC
TTGGCGTGCATGATGGTCATTTTCCTGACGATCGCCTACCTGAAACTGCTACTCCTCAAAAAAT
ACTCCTAAATTCCCCTCTAGGTTACACCACTTACCCCCCATTAAAGAGAAAGCATTCTGGTTTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_999175	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAD12785	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000028287.4
	ENSSSCP00000028560.4
	ENSSSCP00070024187.1
GenBank Protein	Q8MIB3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_999175 ⟸ NM_214010

- UniProtKB:

Q8MIB3 (UniProtKB/Swiss-Prot), A0A5S6GWJ4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSNSYQVSIPMSKRNTNGLPGSSSNELKTSAGGAVLSFHDICYRVKVKSGFLFCRKTVEKEIL
TNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPHGLSGDVLINGAPRPANFKCNSGYVVQDD
VVMGTLTVRENLQFSAALRLPTTMTNHEKNERINMVIQELGLDKVADSKVGTQFIRGVSGGERK
RTSIAMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSL
TLLASGRLMFHGPAREALGYFASIGYNCEPYNNPADFFLDVINGDSSAVVLSRADRDEGAQEPE
EPPEKDTPLIDKLAAFYTNSSFFKDTKVELDQFSGGRKKKKSSVYKEVTYTTSFCHQLRWISRR
SFKNLLGNPQASVAQIIVTIILGLVIGAIFYDLKNDPSGIQNRAGVLFFLTTNQCFSSVSAVEL
LVVEKKLFIHEYISGYYRVSSYFFGKLLSDLLPMRMLPSIIFTCITYFLLGLKPAVGSFFIMMF
TLMMVAYSASSMALAIAAGQSVVSVATLLMTISFVFMMIFSGLLVNLKTVVPWLSWLQYFSIPR
YGFSALQYNEFLGQNFCPGLNVTTNNTCSFAICTGAEYLENQGISLSAWGLWQNHVALACMMVI
FLTIAYLKLLLLKKYS

hide sequence

RefSeq Acc Id:

ENSSSCP00000028560 ⟸ ENSSSCT00000036626

RefSeq Acc Id:

ENSSSCP00000028287 ⟸ ENSSSCT00000036315

Protein Domains

ABC transmembrane type-2 ABC transporter

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000009215	Ensembl, UniProtKB/TrEMBL
	ENSSSCG00070014755	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSSSCT00000036315.4	UniProtKB/TrEMBL
	ENSSSCT00000036626.4	UniProtKB/TrEMBL
	ENSSSCT00070029011.1	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	AAA+_ATPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ABC_2_trans	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ABC_transporter-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ABCG_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	ssc:397073	UniProtKB/Swiss-Prot
NCBI Gene	ABCG2	ENTREZGENE
PANTHER	ABC TRANSPORTER G FAMILY MEMBER 28	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR48041:SF92	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	ABC2_membrane	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ABC2_membrane_7	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ABC_tran	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	ABC_TRANSPORTER_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	AAA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A5S6GWJ4	ENTREZGENE, UniProtKB/TrEMBL
	A0A5S8LCP5_PIG	UniProtKB/TrEMBL
	ABCG2_PIG	UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID	VGNC:111870	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-07-03	ABCG2A	ATP binding cassette subfamily G member 2A	ABCG2	ATP-binding cassette, sub-family G (WHITE), member 2	Symbol and/or name change	19259463	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)