Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of NLRP3 inflammasome complex assembly
go back to main search page
Accession:GO:1900226 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.
Synonyms:exact_synonym: down regulation of NALP3 inflammasome complex assembly;   down regulation of NLRP3 inflammasome complex assembly;   downregulation of NALP3 inflammasome complex assembly;   downregulation of NLRP3 inflammasome complex assembly;   inhibition of NALP3 inflammasome complex assembly;   negative regulation of NALP3 inflammasome complex assembly
 narrow_synonym: inhibition of NLRP3 inflammasome complex assembly
 related_synonym: down regulation of NLRP3 inflammasome activation;   downregulation of NLRP3 inflammasome activation;   inhibition of NLRP3 inflammasome activation;   negative regulation of NLRP3 inflammasome activation


show annotations for term's descendants           Sort by:
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17a abhydrolase domain containing 17A involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:80,419,483...80,426,199
Ensembl chr10:80,419,488...80,426,175 		JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:155,949,180...155,953,897
Ensembl chr 4:155,949,180...155,953,897 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in IDA (MGI:6787653|PMID:34615873) UniProt PMID:34615873 MGI:6787653 NCBI chr18:61,687,307...61,723,391
Ensembl chr18:61,688,345...61,723,132 		JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:113,787,625...113,855,871
Ensembl chr 9:113,792,705...113,875,259 		JBrowse link
G Hspa8 heat shock protein 8 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383 		JBrowse link
G Igtp interferon gamma induced GTPase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:58,090,382...58,098,418
Ensembl chr11:58,090,382...58,098,417 		JBrowse link
G Irgm1 immunity-related GTPase family M member 1 involved_in IDA
ISO		 (MGI:6282153|PMID:30612879) UniProt
MGI		 PMID:30612879 GO_REF:0000119 MGI:4834177 MGI:6282153 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510 		JBrowse link
G Irgm2 immunity-related GTPase family M member 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:58,105,803...58,113,609
Ensembl chr11:58,090,444...58,113,608 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:37,488,524...37,545,337
Ensembl chr  X:37,490,234...37,545,331 		JBrowse link
G Mefv Mediterranean fever involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:3,524,838...3,536,073
Ensembl chr16:3,525,082...3,535,961 		JBrowse link
G mt-Rnr2 16S rRNA, mitochondrial involved_in ISO (PMID:32923762) UniProt PMID:32923762 NCBI chr MT:1,094...2,675
Ensembl chr MT:1,094...2,675 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:3,762,871...3,796,881
Ensembl chr16:3,762,871...3,794,496 		JBrowse link
G Sirt2 sirtuin 2 acts_upstream_of_or_within IMP (PMID:23502856) MGI PMID:23502856 NCBI chr 7:28,466,192...28,488,086
Ensembl chr 7:28,466,160...28,488,086 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within IMP
ISO		 (MGI:6391726|PMID:29887864) ARUK-UCL
MGI		 PMID:29887864 GO_REF:0000119 MGI:4834177 MGI:6391726 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175 		JBrowse link
G Trim30a tripartite motif-containing 30A involved_in IMP (MGI:4868339|PMID:21048113) UniProt PMID:21048113 MGI:4868339 NCBI chr 7:104,058,232...104,114,400
Ensembl chr 7:104,058,232...104,114,400 		JBrowse link
G Trim31 tripartite motif-containing 31 involved_in IDA
ISO		 (MGI:5907951|PMID:27929086) UniProt
MGI		 PMID:27929086 GO_REF:0000119 MGI:4834177 MGI:5907951 NCBI chr17:37,209,022...37,221,109
Ensembl chr17:37,209,010...37,221,106 		JBrowse link
G Zdhhc12 zinc finger, DHHC domain containing 12 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:29,980,956...29,983,647
Ensembl chr 2:29,980,956...29,983,660 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28576
    cellular process 17546
      negative regulation of cellular process 5529
        negative regulation of cellular component organization 823
          negative regulation of protein-containing complex assembly 163
            negative regulation of NLRP3 inflammasome complex assembly 17
Path 2
Term Annotations click to browse term
  biological_process 28576
    response to stimulus 10773
      response to biotic stimulus 2060
        response to external biotic stimulus 2016
          response to other organism 2013
            defense response to other organism 1411
              defense response to symbiont 1281
                innate immune response 1078
                  regulation of innate immune response 501
                    positive regulation of innate immune response 409
                      activation of innate immune response 332
                        innate immune response-activating signaling pathway 295
                          pattern recognition receptor signaling pathway 284
                            cytoplasmic pattern recognition receptor signaling pathway 186
                              inflammasome-mediated signaling pathway 52
                                canonical inflammasome complex assembly 49
                                  NLRP3 inflammasome complex assembly 46
                                    regulation of NLRP3 inflammasome complex assembly 43
                                      negative regulation of NLRP3 inflammasome complex assembly 17
paths to the root