ONTOLOGY REPORT - ANNOTATIONS
Term: phosphorylation-dependent protein binding
Accession: GO:0140031
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Definition: Binding to a protein upon phosphorylation of the target protein.
Comment: This term should only be used when the binding is shown to require phosphorylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of phosphorylation. It may be that the phosphorylation causes a conformational change that allows binding of the protein to another region; this type of phosphorylation-dependent protein binding is valid for annotation to this term.
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Ank2
ankyrin 2
enables
ISO
UniProtKB:B3KU38|UniProtKB:P0DPB3 (PMID:25950943)
RGD
PMID:25950943
NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
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Ank3
ankyrin 3
enables
IPI
PMID:25950943
UniProt
PMID:25950943 PMID:25950943
RGD:13800538 , RGD:13800538
NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
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Lyn
LYN proto-oncogene, Src family tyrosine kinase
enables
ISO
UniProtKB:Q8NDB2 (PMID:11782428)
RGD
PMID:11782428
NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
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Nbn
nibrin
enables
IEA ISS ISO
GO_REF:0000107 GO_REF:0000024 (PMID:18411307), (PMID:18582474), (PMID:18583988), (PMID:18678890), (PMID:19804756), (PMID:24534091), (PMID:27814491), (PMID:30787182)
Ensembl UniProt RGD
PMID:18411307 PMID:18582474 PMID:18583988 PMID:18678890 PMID:19804756 PMID:24534091 PMID:27814491 PMID:30787182 More...
GO_REF:0000024 GO_REF:0000107
NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
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Plcg2
phospholipase C, gamma 2
enables
IEA ISO
GO_REF:0000107 UniProtKB:Q9QZE2 (MGI:2179131|PMID:10744659)
Ensembl RGD
PMID:10744659
GO_REF:0000107 MGI:2179131
NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
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Ptpn6
protein tyrosine phosphatase, non-receptor type 6
enables
ISO IEA
UniProtKB:Q96LA5|UniProtKB:Q96LC7 (PMID:11162587), (PMID:12163025) GO_REF:0000107
RGD Ensembl
PMID:11162587 PMID:12163025
GO_REF:0000107
NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
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Topbp1
DNA topoisomerase II binding protein 1
enables
ISO
(PMID:17575048), (PMID:20545769), (PMID:21482717), (PMID:21777809), (PMID:23891287), (PMID:26811421), (PMID:30898438), (PMID:31135337), (PMID:35597237), (PMID:37674080)
RGD
PMID:17575048 PMID:20545769 PMID:21482717 PMID:21777809 PMID:23891287 PMID:26811421 PMID:30898438 PMID:31135337 PMID:35597237 PMID:37674080 More...
NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674
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Vav1
vav guanine nucleotide exchange factor 1
enables
ISO IEA
UniProtKB:Q9QZE2 (MGI:2179131|PMID:10744659) GO_REF:0000107
RGD Ensembl
PMID:10744659
GO_REF:0000107 MGI:2179131
NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937
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Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
enables
ISO ISS
(PMID:36732624), (PMID:38377992) GO_REF:0000024
RGD UniProt
PMID:36732624 PMID:38377992
GO_REF:0000024
NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
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Thap7
THAP domain containing 7
enables
ISO
(PMID:15561719)
RGD
PMID:15561719
NCBI chr11:83,482,958...83,486,136
Ensembl chr11:83,483,037...83,486,436
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