Gene: Plcg2 (phospholipase C, gamma 2) Rattus norvegicus
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Symbol: Plcg2
Name: phospholipase C, gamma 2
Description: ENCODES a protein that exhibits phosphatidylinositol phospholipase C activity; INVOLVED IN positive regulation of cytosolic calcium ion concentration; response to ATP; response to magnesium ion; PARTICIPATES IN erythropoietin signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; B cell receptor signaling pathway; ASSOCIATED WITH Autoinflammation, Antibody Deficiency, and Immune Dysregulation, PLCG2-Associated (ortholog); Familial Cold Autoinflammatory Syndrome 3 (ortholog); FOUND IN membrane; cytosol (ortholog); extracellular exosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C-gamma-2; phospholipase C-IV; PLC-gamma-2; PLC-IV
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01950,039,410 - 50,173,543 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01960,828,451 - 60,962,641 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41947,875,572 - 47,947,573 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11947,880,452 - 47,952,454 (-)NCBI
Celera1944,819,007 - 44,954,904 (+)NCBI
Cytogenetic Map19q12NCBImapview
RH 3.4 Map19609.8RGD
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Plcg2
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RGD Object Information
RGD ID: 3348
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-11-18
Status: ACTIVE