| 17beta-estradiol | increases expression | ISO | RGD:1553000 | 6480464 | Estradiol results in increased expression of PTPN6 mRNA | CTD | PMID:17578864 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1553000 | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTPN6 gene] | CTD | PMID:20819909 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1553000 | 6480464 | Tetrachlorodibenzodioxin affects the expression of PTPN6 mRNA | CTD | PMID:21570461 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1553000 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PTPN6 mRNA | CTD | PMID:20819909 |
| 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of PTPN6 mRNA | CTD | PMID:21346803 |
| 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1,2-dithiol-3-thione results in decreased expression of PTPN6 mRNA | CTD | PMID:19162173 |
| 5-aza-2'-deoxycytidine | decreases methylation | ISO | RGD:734188 | 6480464 | decitabine results in decreased methylation of PTPN6 promoter | CTD | PMID:19551406 |
| 5-aza-2'-deoxycytidine | increases expression | ISO | RGD:734188 | 6480464 | decitabine results in increased expression of PTPN6 mRNA | CTD | PMID:19379557 more ... |
| 5-aza-2'-deoxycytidine | increases expression | ISO | RGD:734188 | 6480464 | decitabine results in increased expression of PTPN6 protein | CTD | PMID:19379557 more ... |
| 5-aza-2'-deoxycytidine | increases expression | ISO | RGD:734188 | 6480464 | decitabine results in increased expression of PTPN6 mRNA; more ... | CTD | PMID:17343198 more ... |
| 5-aza-2'-deoxycytidine | increases expression | ISO | RGD:734188 | 6480464 | decitabine results in increased expression of PTPN6 protein; more ... | CTD | PMID:19551406 more ... |
| 5-aza-2'-deoxycytidine | increases expression | ISO | RGD:734188 | 6480464 | decitabine results in increased expression of PTPN6 mRNA; more ... | CTD | PMID:17343198 more ... |
| 5-aza-2'-deoxycytidine | increases expression | ISO | RGD:734188 | 6480464 | decitabine results in increased expression of PTPN6 mRNA; more ... | CTD | PMID:19551406 more ... |
| afimoxifene | decreases activity | ISO | RGD:734188 | 6480464 | 4-hydroxytamoxifen results in decreased activity of PTPN6 protein; more ... | CTD | PMID:17272397 |
| all-trans-retinol | multiple interactions | EXP | | 6480464 | Vitamin A affects the localization of and affects the phosphorylation of PTPN6 protein | CTD | PMID:15963505 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PTPN6 mRNA | CTD | PMID:16483693 |
| benzo[a]pyrene | decreases expression | ISO | RGD:1553000 | 6480464 | Benzo(a)pyrene results in decreased expression of PTPN6 mRNA | CTD | PMID:21569818 |
| benzo[a]pyrene | increases expression | ISO | RGD:1553000 | 6480464 | Benzo(a)pyrene results in increased expression of PTPN6 mRNA | CTD | PMID:22228805 |
| bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PTPN6 mRNA | CTD | PMID:18180321 |
| chlordecone | increases expression | ISO | RGD:1553000 | 6480464 | Chlordecone results in increased expression of PTPN6 mRNA | CTD | PMID:17578864 |
| chloroprene | decreases expression | ISO | RGD:1553000 | 6480464 | Chloroprene results in decreased expression of PTPN6 mRNA | CTD | PMID:23125180 |
| clofibrate | increases expression | ISO | RGD:1553000 | 6480464 | Clofibrate results in increased expression of PTPN6 mRNA | CTD | PMID:17585979 |
| copper(2+) sulfate | decreases expression | ISO | RGD:734188 | 6480464 | Copper Sulfate results in decreased expression of PTPN6 mRNA | CTD | PMID:19549813 |
| curcumin | increases expression | ISO | RGD:734188 | 6480464 | Curcumin results in increased expression of PTPN6 mRNA | CTD | PMID:17198877 |
| cyclosporin A | decreases expression | ISO | RGD:734188 | 6480464 | Cyclosporine results in decreased expression of PTPN6 mRNA | CTD | PMID:20106945 |
| diarsenic trioxide | decreases methylation | ISO | RGD:734188 | 6480464 | arsenic trioxide results in decreased methylation of PTPN6 promoter | CTD | PMID:19950550 |
| diarsenic trioxide | increases expression | ISO | RGD:734188 | 6480464 | arsenic trioxide results in increased expression of PTPN6 mRNA | CTD | PMID:19950550 |
| diarsenic trioxide | multiple interactions | ISO | RGD:734188 | 6480464 | arsenic trioxide results in decreased methylation of and results in increased expression of PTPN6 | CTD | PMID:19619438 |
| elemental selenium | multiple interactions | ISO | RGD:734188 | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of PTPN6 mRNA | CTD | PMID:19244175 |
| elemental selenium | increases expression | ISO | RGD:734188 | 6480464 | Selenium results in increased expression of PTPN6 mRNA | CTD | PMID:19244175 |
| ethanol | multiple interactions | EXP | | 6480464 | [Fish Oils co-treated with Ethanol] results in increased expression of PTPN6 mRNA | CTD | PMID:17347304 |
| fonofos | increases methylation | ISO | RGD:734188 | 6480464 | Fonofos results in increased methylation of PTPN6 promoter | CTD | PMID:22847954 |
| hydrogen peroxide | affects expression | ISO | RGD:734188 | 6480464 | Hydrogen Peroxide affects the expression of PTPN6 mRNA | CTD | PMID:20044591 |
| hydrogen peroxide | decreases response to substance | ISO | RGD:1553000 | 6480464 | PTPN6 protein results in decreased susceptibility to Hydrogen Peroxide | CTD | PMID:18441283 |
| hydrogen peroxide | multiple interactions | ISO | RGD:1553000 | 6480464 | PTPN6 protein inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of NFKBIA protein]; more ... | CTD | PMID:18441283 |
| hydrogen peroxide | multiple interactions | ISO | RGD:734188 | 6480464 | PTPN6 protein inhibits the reaction [Hydrogen Peroxide results in increased expression of CCL20 protein]; more ... | CTD | PMID:18441283 |
| lead diacetate | decreases expression | ISO | RGD:1553000 | 6480464 | lead acetate results in decreased expression of PTPN6 mRNA | CTD | PMID:22609695 |
| methoxychlor | increases methylation | EXP | | 6480464 | Methoxychlor results in increased methylation of PTPN6 gene | CTD | PMID:23303685 |
| paraquat | multiple interactions | ISO | RGD:1553000 | 6480464 | PTPN6 protein inhibits the reaction [Paraquat results in increased expression of CCL20 protein]; more ... | CTD | PMID:18441283 |
| parathion | increases methylation | ISO | RGD:734188 | 6480464 | Parathion results in increased methylation of PTPN6 promoter | CTD | PMID:22847954 |
| PD123319 | multiple interactions | EXP | | 6480464 | PD 123319 affects the reaction [AGT protein promotes the reaction [PTPN6 protein binds to MTUS1 protein]] | CTD | PMID:17068200 |
| pirinixic acid | increases expression | ISO | RGD:1553000 | 6480464 | pirinixic acid results in increased expression of PTPN6 mRNA | CTD | PMID:20813756 PMID:18301758 |
| pirinixic acid | increases expression | ISO | RGD:1553000 | 6480464 | pirinixic acid results in increased expression of PTPN6 mRNA | CTD | PMID:18301758 PMID:20813756 |
| raloxifene | decreases activity | ISO | RGD:734188 | 6480464 | Raloxifene results in decreased activity of PTPN6 protein | CTD | PMID:17272397 |
| selenium atom | multiple interactions | ISO | RGD:734188 | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of PTPN6 mRNA | CTD | PMID:19244175 |
| selenium atom | increases expression | ISO | RGD:734188 | 6480464 | Selenium results in increased expression of PTPN6 mRNA | CTD | PMID:19244175 |
| terbufos | increases methylation | ISO | RGD:734188 | 6480464 | terbufos results in increased methylation of PTPN6 promoter | CTD | PMID:22847954 |
| trimethyltin | increases expression | ISO | RGD:1553000 | 6480464 | trimethyltin results in increased expression of PTPN6 mRNA | CTD | PMID:20833246 |
| valsartan | multiple interactions | EXP | | 6480464 | valsartan promotes the reaction [AGT protein promotes the reaction [PTPN6 protein binds to MTUS1 protein]] | CTD | PMID:17068200 |