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ONTOLOGY REPORT - ANNOTATIONS

Term:adenylate cyclase-activating adrenergic receptor signaling pathway
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Accession:GO:0071880 term browser browse the term
Definition:An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.
Synonyms:exact_synonym: activation of adenylate cyclase activity by adrenergic receptor signalling pathway;   adrenergic receptor, adenylate cyclase activating pathway;   adrenergic receptor, adenylyl cyclase activating pathway
 related_synonym: activation of adenylate cyclase activity by adrenergic receptor signaling pathway


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adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy9 adenylate cyclase 9 involved_in ISO (PMID:9628827) RGD PMID:9628827 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066 		JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra1b adrenoceptor alpha 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Adra1d adrenoceptor alpha 1D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO
IBA		 (PMID:12529373)
GO_REF:0000033		 RGD
GO_Central		 PMID:12529373 GO_REF:0000033 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adra2b adrenoceptor alpha 2B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355 		JBrowse link
G Adra2c adrenoceptor alpha 2C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846 		JBrowse link
G Adrb1 adrenoceptor beta 1 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:10212248), (PMID:12391161), (PMID:12529373)
GO_REF:0000033		 UniProt
Ensembl
RGD
GO_Central		 PMID:10212248 PMID:12391161 PMID:12529373 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in IBA
ISO		 GO_REF:0000033
(PMID:15123695)		 GO_Central
RGD		 PMID:15123695 GO_REF:0000033 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Adrb3 adrenoceptor beta 3 involved_in IBA
ISO
ISS		 GO_REF:0000033
(PMID:15123695)
GO_REF:0000024		 GO_Central
RGD
HGNC-UCL		 PMID:15123695 GO_REF:0000024 GO_REF:0000033 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Drd2 dopamine receptor D2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd5 dopamine receptor D5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Gnas GNAS complex locus involved_in ISS
ISO		 GO_REF:0000024
(PMID:12391161)		 UniProt
RGD		 PMID:12391161 GO_REF:0000024 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gpr101 G protein-coupled receptor 101 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:135,540,042...135,543,958
Ensembl chr  X:135,540,042...135,543,958 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISO
ISS		 (PMID:12391161)
GO_REF:0000024		 RGD
UniProt		 PMID:12391161 GO_REF:0000024 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chga chromogranin A involved_in IDA
IBA		 PMID:22459152
GO_REF:0000033		 GO_Central PMID:22459152 GO_REF:0000033, RGD:6906968 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap13 A-kinase anchoring protein 13 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5770047|PMID:23658642)		 UniProt
RGD		 PMID:23658642 GO_REF:0000024 MGI:5770047 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646 		JBrowse link
G Pln phospholamban acts_upstream_of_or_within ISO MGI:2158357 (PMID:10471356) RGD PMID:10471356 NCBI chr20:32,629,537...32,639,559 JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrdc3 arrestin domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3877613 (PMID:21982743)		 Ensembl
RGD		 PMID:21982743 GO_REF:0000107 NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:17242280) RGD PMID:17242280 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 acts_upstream_of_or_within ISO (PMID:21164481) RGD PMID:21164481 NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500 		JBrowse link
G Gnai2 G protein subunit alpha i2 IDA RGD PMID:12631586 RGD:13508593 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Pde4b phosphodiesterase 4B involved_in IEA
ISO		 GO_REF:0000107
(MGI:5286798|PMID:21670503)		 Ensembl
RGD		 PMID:21670503 GO_REF:0000107 MGI:5286798 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18196
      signal transduction 7019
        G protein-coupled receptor signaling pathway 2423
          adrenergic receptor signaling pathway 34
            adenylate cyclase-activating adrenergic receptor signaling pathway 24
              adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process + 3
              negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 19692
    biological regulation 13309
      regulation of biological process 12906
        regulation of cellular process 12363
          signal transduction 7019
            G protein-coupled receptor signaling pathway 2423
              adenylate cyclase-modulating G protein-coupled receptor signaling pathway 252
                adenylate cyclase-activating G protein-coupled receptor signaling pathway 171
                  adenylate cyclase-activating adrenergic receptor signaling pathway 24
                    adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process + 3
                    negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway + 5
paths to the root