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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of type I interferon-mediated signaling pathway
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Accession:GO:0060338 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway.
Synonyms:exact_synonym: regulation of type I interferon-mediated signalling pathway


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regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc37 cell division cycle 37 acts_upstream_of_or_within ISO (PMID:16280321) MGI PMID:16280321 NCBI chr 9:21,050,727...21,061,230
Ensembl chr 9:21,044,518...21,061,278 		JBrowse link
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific acts_upstream_of_or_within IMP (PMID:19060901) MGI PMID:19060901 NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:81,156,937...81,162,085
Ensembl chr10:81,156,937...81,162,076 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:40,945,579...40,968,888
Ensembl chr 8:40,945,581...40,968,888 		JBrowse link
G Dcst1 DC-STAMP domain containing 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:89,257,526...89,272,560
Ensembl chr 3:89,257,526...89,272,560 		JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E member 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:87,141,633...87,168,210
Ensembl chr 1:87,141,636...87,168,210 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:87,254,653...87,378,532
Ensembl chr 1:87,254,720...87,378,518 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:52,532,298...52,548,555
Ensembl chr14:52,532,298...52,542,585 		JBrowse link
G Mir21a microRNA 21a involved_in ISO (PMID:23633945) BHF-UCL PMID:23633945 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IMP (MGI:5583923|PMID:24784232) CAFA PMID:24784232 MGI:5583923 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499 		JBrowse link
G Mul1 mitochondrial ubiquitin ligase activator of NFKB 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:138,160,239...138,169,576
Ensembl chr 4:138,161,982...138,169,576 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in IDA
IBA
ISO		 (MGI:4454346|PMID:20434986) UniProt
GO_Central
MGI		 PMID:20434986 GO_REF:0000033 GO_REF:0000119 MGI:4454346 MGI:4834177 NCBI chr 8:95,160,963...95,253,900
Ensembl chr 8:95,160,984...95,253,900 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:121,034,319...121,045,588
Ensembl chr 5:121,034,319...121,045,584 		JBrowse link
G Oas1b 2'-5' oligoadenylate synthetase 1B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:120,950,700...120,962,228
Ensembl chr 5:120,950,700...120,962,228 		JBrowse link
G Oas1c 2'-5' oligoadenylate synthetase 1C involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:120,938,259...120,950,605
Ensembl chr 5:120,938,259...120,950,579 		JBrowse link
G Oas1d 2'-5' oligoadenylate synthetase 1D involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:121,052,881...121,059,711
Ensembl chr 5:121,052,599...121,059,715 		JBrowse link
G Oas1e 2'-5' oligoadenylate synthetase 1E involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:120,924,377...120,933,595
Ensembl chr 5:120,924,291...120,933,595 		JBrowse link
G Oas1f 2'-5' oligoadenylate synthetase 1F involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:120,985,432...120,996,049
Ensembl chr 5:120,985,432...120,996,049 		JBrowse link
G Oas1g 2'-5' oligoadenylate synthetase 1G involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:121,014,205...121,025,676
Ensembl chr 5:121,014,205...121,025,676 		JBrowse link
G Oas1h 2'-5' oligoadenylate synthetase 1H involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:120,999,485...121,011,569
Ensembl chr 5:120,999,484...121,011,569 		JBrowse link
G Oas3 2'-5' oligoadenylate synthetase 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:120,891,163...120,915,755
Ensembl chr 5:120,891,163...120,915,726 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in IMP
ISO		 (MGI:3691503|PMID:11909529), (MGI:5493216|PMID:12138178) UniProt
MGI		 PMID:11909529 PMID:12138178 GO_REF:0000119 MGI:3691503 MGI:4834177 MGI:5493216 NCBI chr18:67,798,571...67,857,697
Ensembl chr18:67,798,581...67,857,665 		JBrowse link
G Samhd1 SAM domain and HD domain, 1 involved_in IMP
ISO		 (MGI:5521417|PMID:23972988) UniProt
MGI		 PMID:23972988 GO_REF:0000119 MGI:4834177 MGI:5521417 NCBI chr 2:156,939,454...156,977,016
Ensembl chr 2:156,939,453...156,977,185 		JBrowse link
G Smim30 small integral membrane protein 30 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:13,867,734...13,871,517
Ensembl chr 6:13,867,734...13,871,517 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 involved_in IMP
ISO		 (MGI:6508512|PMID:28165510) UniProt
MGI		 PMID:28165510 GO_REF:0000119 MGI:4834177 MGI:6508512 NCBI chr10:128,106,367...128,128,722
Ensembl chr10:128,106,428...128,128,718 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within IMP (PMID:18724932) MGI PMID:18724932 NCBI chr 9:108,887,000...108,888,791
Ensembl chr 9:108,887,001...108,888,802 		JBrowse link
G Ttll12 tubulin tyrosine ligase-like family, member 12 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:83,459,295...83,479,358
Ensembl chr15:83,459,291...83,479,358 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 involved_in ISO (PMID:28165510) UniProt PMID:28165510 NCBI chr 6:121,222,865...121,247,876
Ensembl chr 6:121,222,865...121,247,876 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:131,912,227...131,939,567
Ensembl chr 4:131,912,223...131,939,614 		JBrowse link
G Ythdf3 YTH N6-methyladenosine RNA binding protein 3 involved_in IMP (MGI:6316470|PMID:30591559) UniProt PMID:30591559 MGI:6316470 NCBI chr 3:16,237,309...16,271,201
Ensembl chr 3:16,237,376...16,271,201 		JBrowse link
positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200 		JBrowse link
G Ikbke inhibitor of kappaB kinase epsilon involved_in IMP
ISO		 (MGI:5792628|PMID:27129230) UniProt
MGI		 PMID:27129230 GO_REF:0000119 MGI:4834177 MGI:5792628 NCBI chr 1:131,182,337...131,207,339
Ensembl chr 1:131,182,080...131,207,344 		JBrowse link
G Irf3 interferon regulatory factor 3 acts_upstream_of_or_within IMP (PMID:17618271) MGI PMID:17618271 NCBI chr 7:44,647,072...44,652,272
Ensembl chr 7:44,647,072...44,652,272 		JBrowse link
G Irf7 interferon regulatory factor 7 acts_upstream_of_or_within IMP (PMID:17618271) MGI PMID:17618271 NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor acts_upstream_of_or_within IDA (PMID:22745163) MGI PMID:22745163 NCBI chr 7:34,043,569...34,089,134
Ensembl chr 7:34,044,071...34,092,740 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IMP (MGI:5583923|PMID:24784232) CAFA PMID:24784232 MGI:5583923 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:95,160,963...95,253,900
Ensembl chr 8:95,160,984...95,253,900 		JBrowse link
G Rbm47 RNA binding motif protein 47 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:66,173,892...66,309,297
Ensembl chr 5:66,173,892...66,330,461 		JBrowse link
G Rfpl4b ret finger protein-like 4B involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:38,696,537...38,697,775
Ensembl chr10:38,696,537...38,697,775 		JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:3,365,973...3,402,956
Ensembl chr11:3,365,982...3,402,363 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in IDA
ISO		 (MGI:6827194|PMID:23910378) ComplexPortal
MGI		 PMID:23910378 GO_REF:0000119 MGI:4834177 MGI:6827194 NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in IMP (MGI:5792628|PMID:27129230) UniProt PMID:27129230 MGI:5792628 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692 		JBrowse link
G Trim41 tripartite motif-containing 41 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:48,697,230...48,709,026
Ensembl chr11:48,697,231...48,708,180 		JBrowse link
G Trim56 tripartite motif-containing 56 involved_in IDA
ISO
IBA		 (MGI:6119245|PMID:29426904) UniProt
MGI
GO_Central		 PMID:29426904 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6119245 NCBI chr 5:137,140,140...137,145,313
Ensembl chr 5:137,134,498...137,145,063 		JBrowse link
G Trim6 tripartite motif-containing 6 involved_in IMP
ISO		 (MGI:5645191|PMID:24882218) UniProt
MGI		 PMID:24882218 GO_REF:0000119 MGI:4834177 MGI:5645191 NCBI chr 7:103,868,002...103,884,359
Ensembl chr 7:103,868,000...103,884,359 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:65,694,588...65,756,332
Ensembl chr 5:65,694,576...65,756,331 		JBrowse link
G Usp27x ubiquitin specific peptidase 27, X chromosome involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:7,238,830...7,242,069
Ensembl chr  X:7,237,513...7,242,069 		JBrowse link
G Usp29 ubiquitin specific peptidase 29 involved_in IDA (MGI:6761183|PMID:32457395) UniProt PMID:32457395 MGI:6761183 NCBI chr 7:6,733,560...6,970,219
Ensembl chr 7:6,733,577...6,970,218 		JBrowse link
G Wnt5a wingless-type MMTV integration site family, member 5A involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:17618271) GO_Central
MGI		 PMID:17618271 GO_REF:0000033 NCBI chr 2:173,048,405...173,060,715
Ensembl chr 2:173,048,405...173,060,716 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28577
    cellular process 17497
      signal transduction 6663
        regulation of signal transduction 3285
          regulation of cytokine-mediated signaling pathway 182
            regulation of type I interferon-mediated signaling pathway 50
              negative regulation of type I interferon-mediated signaling pathway 31
              positive regulation of type I interferon-mediated signaling pathway 21
Path 2
Term Annotations click to browse term
  biological_process 28577
    response to stimulus 10767
      response to external stimulus 2932
        response to external biotic stimulus 2016
          response to other organism 2013
            defense response to other organism 1411
              defense response to symbiont 1281
                innate immune response 1079
                  response to type I interferon 80
                    cellular response to type I interferon 74
                      type I interferon-mediated signaling pathway 70
                        regulation of type I interferon-mediated signaling pathway 50
                          negative regulation of type I interferon-mediated signaling pathway 31
                          positive regulation of type I interferon-mediated signaling pathway 21
paths to the root