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ONTOLOGY REPORT - ANNOTATIONS

Term:negative thymic T cell selection
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Accession:GO:0045060 term browser browse the term
Definition:The process of elimination of immature T cells in the thymus which react strongly with self-antigens.
Synonyms:exact_synonym: negative thymic T lymphocyte selection


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negative thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1277186 (PMID:23382543)		 GO_Central
RGD		 PMID:23382543 GO_REF:0000033 NCBI chr20:10,636,058...10,651,060
Ensembl chr20:10,636,123...10,651,060 		JBrowse link
G Atg5 autophagy related 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1338803|MGI:3612279 (PMID:23382543)		 Ensembl
RGD		 PMID:23382543 GO_REF:0000107 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (MGI:3847607|PMID:17785582) RGD PMID:17785582 MGI:3847607 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309 		JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (PMID:10429671) RGD PMID:10429671 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:7630421) RGD PMID:7630421 NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022 		JBrowse link
G Cd74 CD74 molecule acts_upstream_of_or_within ISO MGI:1927205 (PMID:7679955) RGD PMID:7679955 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Dock2 dedicator of cytokinesis 2 acts_upstream_of_or_within ISO MGI:2152031 (PMID:12871644) RGD PMID:12871644 NCBI chr10:18,827,237...19,244,832
Ensembl chr10:18,827,239...19,244,808 		JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO MGI:1856334 (PMID:10429671) RGD PMID:10429671 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO (MGI:4355451|PMID:19667090) RGD PMID:19667090 MGI:4355451 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Mink1 misshapen-like kinase 1 acts_upstream_of_or_within ISO (PMID:15608642) RGD PMID:15608642 NCBI chr10:55,278,293...55,330,782
Ensembl chr10:55,278,391...55,330,782 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:1857277 (PMID:8666928) RGD PMID:8666928 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3834308|PMID:17227833)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17227833 GO_REF:0000024 GO_REF:0000107 MGI:3834308 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO MGI:1857246 (PMID:10429671) RGD PMID:10429671 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO MGI:2677447 (PMID:7630421) RGD PMID:7630421 NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    immune system process 2822
      T cell selection 58
        negative T cell selection 15
          negative thymic T cell selection 14
Path 2
Term Annotations click to browse term
  biological_process 19692
    cellular process 18195
      cellular developmental process 4695
        cell differentiation 4694
          cell development 3269
            hemopoiesis 1061
              leukocyte differentiation 674
                mononuclear cell differentiation 544
                  lymphocyte differentiation 447
                    T cell differentiation 324
                      T cell selection 58
                        negative T cell selection 15
                          negative thymic T cell selection 14
paths to the root