T cell differentiation - Ontology Browser

Keyword

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Term:	T cell differentiation	go back to main search page
Accession:	GO:0030217	browse the term view annotations
Definition:	The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
Comment:	This term was improved by GO_REF:0000022. It was moved. Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:	exact_synonym:	T lymphocyte differentiation
	related_synonym:	T cell development
	alt_id:	GO:0042112; GO:0046652

Parent Terms	Term With Siblings	Child Terms
lymphocyte differentiation + T cell activation +	alpha-beta T cell activation + B cell differentiation + establishment of T cell polarity gamma-delta T cell activation + memory T cell activation + natural killer cell differentiation + negative regulation of lymphocyte differentiation + negative regulation of T cell activation + positive regulation of lymphocyte differentiation + positive regulation of T cell activation + regulation of lymphocyte differentiation + regulation of T cell activation + T cell activation involved in immune response + T cell differentiation + The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. T cell proliferation +	alpha-beta T cell differentiation + cytotoxic T cell differentiation + extrathymic T cell differentiation + gamma-delta T cell differentiation + negative regulation of T cell differentiation + positive regulation of T cell differentiation + pro-T cell differentiation + regulation of T cell differentiation + regulatory T cell differentiation + somatic diversification of T cell receptor genes + T cell differentiation in thymus + T cell differentiation involved in immune response + T cell lineage commitment + T cell selection +