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ONTOLOGY REPORT - ANNOTATIONS

Term:porphyrin-containing compound metabolic process
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Accession:GO:0006778 term browser browse the term
Definition:The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
Synonyms:related_synonym: porphyrin metabolic process;   porphyrin metabolism


show annotations for term's descendants           Sort by:
porphyrin-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP-binding cassette, sub-family B member 6 involved_in IDA
ISO		 (MGI:5898211|PMID:27507172) UniProt
MGI		 PMID:27507172 GO_REF:0000119 MGI:4834177 MGI:5898211 NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036 		JBrowse link
G Alas1 aminolevulinic acid synthase 1 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853 		JBrowse link
G Alas2 aminolevulinic acid synthase 2, erythroid involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr  X:149,330,443...149,353,614
Ensembl chr  X:149,330,371...149,353,634 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 involved_in ISO Uroporphyrinogen oxidation, generating hydrogen peroxide RGD
MGI		 PMID:12907239 GO_REF:0000096 MGI:4417868 RGD:2306674 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 acts_upstream_of_or_within IMP (PMID:11274970), (PMID:9461503) MGI PMID:9461503 PMID:11274970 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in ISO Uroporphyrinogen
Porphobilinogen
Uroporphyrinogen 		RGD
MGI		 PMID:593266 PMID:971328 PMID:994723 PMID:1781034 PMID:3179323 More... GO_REF:0000096 MGI:4417868 RGD:2301707 RGD:25394583 RGD:25394584 RGD:25440495 RGD:25440497 RGD:26884337 RGD:26923962 RGD:26923963 RGD:4144783 RGD:4144803 RGD:4144820 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525 		JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 acts_upstream_of_or_within IMP (PMID:4404581) MGI PMID:4404581 NCBI chr15:100,285,779...100,322,090
Ensembl chr15:100,285,779...100,322,953 		JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610 		JBrowse link
heme A biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate, delta-, dehydratase involved_in IMP
IDA		 (PMID:5393940)
(PMID:14050799)		 MGI PMID:5393940 PMID:14050799 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Alas1 aminolevulinic acid synthase 1 involved_in IMP (PMID:33307066) MGI PMID:33307066 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853 		JBrowse link
G Cox10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 involved_in
acts_upstream_of_or_within		 ISO
IDA
IBA
IGI
IMP		 (PMID:16103131)
(PMID:12928484)
(PMID:16782876)		 MGI
GO_Central		 PMID:12928484 PMID:16103131 PMID:16782876 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:63,853,453...63,970,298
Ensembl chr11:63,853,453...63,970,294 		JBrowse link
G Cox15 cytochrome c oxidase assembly protein 15 involved_in IBA
ISO		 (PMID:12474143) GO_Central
MGI		 PMID:12474143 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr19:43,721,693...43,741,439
Ensembl chr19:43,721,693...43,741,439 		JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IDA (PMID:8407975) MGI PMID:8407975 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999 		JBrowse link
G Fech ferrochelatase involved_in IMP (PMID:15677551) MGI PMID:15677551 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IMP (PMID:8563760) MGI PMID:8563760 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IDA (PMID:3346226) MGI PMID:3346226 NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760 		JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IMP (PMID:17360334) MGI PMID:17360334 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610 		JBrowse link
G Uros uroporphyrinogen III synthase involved_in IMP (PMID:16532394) MGI PMID:16532394 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801 		JBrowse link
heme B biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP-binding cassette, sub-family B member 6 NOT|involved_in ISO (PMID:22655043) UniProt PMID:22655043 NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036 		JBrowse link
G Alad aminolevulinate, delta-, dehydratase involved_in IDA
IMP		 (PMID:14050799)
(PMID:5393940)		 MGI PMID:5393940 PMID:14050799 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Alas1 aminolevulinic acid synthase 1 involved_in IMP (PMID:33307066) MGI PMID:33307066 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853 		JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IDA (PMID:8407975) MGI PMID:8407975 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999 		JBrowse link
G Fech ferrochelatase involved_in IMP (PMID:15677551) MGI PMID:15677551 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IMP (PMID:8563760) MGI PMID:8563760 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IDA (PMID:3346226) MGI PMID:3346226 NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760 		JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IMP (PMID:17360334) MGI PMID:17360334 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610 		JBrowse link
G Uros uroporphyrinogen III synthase involved_in IMP (PMID:16532394) MGI PMID:16532394 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801 		JBrowse link
heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb10 ATP-binding cassette, sub-family B member 10 involved_in IMP (MGI:5648801|PMID:24421385) UniProt PMID:24421385 MGI:5648801 NCBI chr 8:124,679,198...124,709,877
Ensembl chr 8:124,679,198...124,709,861 		JBrowse link
G Alad aminolevulinate, delta-, dehydratase acts_upstream_of_or_within
involved_in		 ISO
IDA
IBA		 (PMID:14050799), (PMID:4959158), (PMID:4981581) RGD
MGI
GO_Central		 PMID:1764448 PMID:4959158 PMID:4981581 PMID:14050799 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1599020 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Alas1 aminolevulinic acid synthase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853 		JBrowse link
G Alas2 aminolevulinic acid synthase 2, erythroid involved_in IMP
IBA		 (MGI:3694153|PMID:9446639) UniProt
GO_Central		 PMID:9446639 GO_REF:0000033 MGI:3694153 NCBI chr  X:149,330,443...149,353,614
Ensembl chr  X:149,330,371...149,353,634 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in IMP
IBA
ISO		 (MGI:5447588|PMID:23135403) UniProt
GO_Central
MGI		 PMID:23135403 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:5447588 NCBI chr 4:132,257,870...132,262,746
Ensembl chr 4:132,257,866...132,260,970 		JBrowse link
G Cox10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 involved_in
acts_upstream_of_or_within		 IEA UniProt GO_REF:0000002 GO_REF:0000043 MGI:1354194 MGI:2152098 NCBI chr11:63,853,453...63,970,298
Ensembl chr11:63,853,453...63,970,294 		JBrowse link
G Cpox coproporphyrinogen oxidase acts_upstream_of_or_within
involved_in		 ISO
IDA		 (PMID:8407975) RGD
MGI		 PMID:3955059 PMID:8407975 GO_REF:0000096 MGI:4417868 RGD:1600961 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within
involved_in		 ISO
TAS
IDA
IBA
IMP		 (PMID:12149233)
(PMID:15496139), (PMID:16503645)
(PMID:16306232)
(PMID:9989256)
(PMID:8611576)		 RGD
MGI
GO_Central		 PMID:3955059 PMID:8611576 PMID:9989256 PMID:12149233 PMID:15496139 More... GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1600961 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322 		JBrowse link
G Fxn frataxin acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr19:24,236,909...24,257,954
Ensembl chr19:24,238,817...24,257,969 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525 		JBrowse link
G Hnf1a HNF1 homeobox A acts_upstream_of_or_within IMP (PMID:10617683) MGI PMID:10617683 NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153 		JBrowse link
G Iba57 IBA57 homolog, iron-sulfur cluster assembly acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr11:59,046,194...59,055,391
Ensembl chr11:59,046,195...59,054,565 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:35,861,846...35,869,732
Ensembl chr  X:35,861,859...35,869,732 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in
acts_upstream_of_or_within		 ISO
IBA
IDA		 (PMID:3346226) RGD
GO_Central
MGI		 PMID:3346226 PMID:3955059 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1600961 NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760 		JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 acts_upstream_of_or_within IMP (PMID:11739192) MGI PMID:11739192 NCBI chr15:100,285,779...100,322,090
Ensembl chr15:100,285,779...100,322,953 		JBrowse link
G Slc25a39 solute carrier family 25, member 39 acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr11:102,293,795...102,299,501
Ensembl chr11:102,293,811...102,298,772 		JBrowse link
G Snx3 sorting nexin 3 acts_upstream_of_or_within ISO (PMID:23416069) MGI PMID:23416069 NCBI chr10:42,378,050...42,411,365
Ensembl chr10:42,378,026...42,411,377 		JBrowse link
G Srrd SRR1 domain containing acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr 5:112,485,257...112,490,921
Ensembl chr 5:112,485,258...112,490,906 		JBrowse link
G Tmem14c transmembrane protein 14C acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr13:41,169,726...41,176,058
Ensembl chr13:41,169,768...41,176,062 		JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:17360334) GO_Central
MGI		 PMID:17360334 GO_REF:0000033 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610 		JBrowse link
G Uros uroporphyrinogen III synthase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801 		JBrowse link
heme catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blvra biliverdin reductase A involved_in
acts_upstream_of_or_within		 ISO (PMID:12079357) MGI PMID:12079357 GO_REF:0000119 MGI:4834177 NCBI chr 2:126,912,549...126,939,004
Ensembl chr 2:126,912,585...126,939,004 		JBrowse link
G Blvrb biliverdin reductase B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:27,147,403...27,165,406
Ensembl chr 7:27,147,403...27,165,569 		JBrowse link
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within
involved_in		 ISO
IGI
IBA		 (PMID:31571584) RGD
MGI
GO_Central		 PMID:15226268 PMID:31571584 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1547877 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hmox2 heme oxygenase 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606 		JBrowse link
heme metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP-binding cassette, sub-family B member 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036 		JBrowse link
G Cyb5r4 cytochrome b5 reductase 4 acts_upstream_of_or_within ISO (PMID:10611283) MGI PMID:10611283 NCBI chr 9:86,904,082...86,959,827
Ensembl chr 9:86,904,067...86,959,827 		JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 acts_upstream_of_or_within IDA (PMID:16183037) MGI PMID:16183037 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973 		JBrowse link
G Hebp1 heme binding protein 1 acts_upstream_of_or_within IC (PMID:12413491), (PMID:9813049) MGI PMID:9813049 PMID:12413491 NCBI chr 6:135,114,517...135,145,213
Ensembl chr 6:135,114,520...135,175,020 		JBrowse link
G Hmox1 heme oxygenase 1 acts_upstream_of_or_within IDA (PMID:16183037) MGI PMID:16183037 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hpx hemopexin involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:18556779) GO_Central
MGI		 PMID:18556779 GO_REF:0000033 NCBI chr 7:105,240,818...105,249,323
Ensembl chr 7:105,240,820...105,249,344 		JBrowse link
G Slc48a1 solute carrier family 48 (heme transporter), member 1 involved_in IMP (PMID:31571584) MGI PMID:31571584 NCBI chr15:97,682,246...97,690,573
Ensembl chr15:97,676,401...97,690,573 		JBrowse link
G Slco1a6 solute carrier organic anion transporter family, member 1a6 acts_upstream_of_or_within IMP (PMID:20644253) MGI PMID:20644253 NCBI chr 6:142,031,487...142,131,903
Ensembl chr 6:142,031,487...142,154,247 		JBrowse link
G Urod uroporphyrinogen decarboxylase acts_upstream_of_or_within IMP (PMID:11134514) MGI PMID:11134514 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610 		JBrowse link
heme O biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate, delta-, dehydratase involved_in IDA
IMP		 (PMID:14050799)
(PMID:5393940)		 MGI PMID:5393940 PMID:14050799 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Alas1 aminolevulinic acid synthase 1 involved_in IMP (PMID:33307066) MGI PMID:33307066 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853 		JBrowse link
G Cox10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 involved_in IGI (PMID:12928484) MGI PMID:12928484 NCBI chr11:63,853,453...63,970,298
Ensembl chr11:63,853,453...63,970,294 		JBrowse link
G Cpox coproporphyrinogen oxidase involved_in IDA (PMID:8407975) MGI PMID:8407975 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999 		JBrowse link
G Fech ferrochelatase involved_in IMP (PMID:15677551) MGI PMID:15677551 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in IMP (PMID:8563760) MGI PMID:8563760 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in IDA (PMID:3346226) MGI PMID:3346226 NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760 		JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in IMP (PMID:17360334) MGI PMID:17360334 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610 		JBrowse link
G Uros uroporphyrinogen III synthase involved_in IMP (PMID:16532394) MGI PMID:16532394 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801 		JBrowse link
heme oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hmox2 heme oxygenase 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606 		JBrowse link
porphyrin-containing compound biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP-binding cassette, sub-family B member 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036 		JBrowse link
G Alad aminolevulinate, delta-, dehydratase acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Ank1 ankyrin 1, erythroid acts_upstream_of_or_within IMP (PMID:658175) MGI PMID:658175 NCBI chr 8:23,464,852...23,640,517
Ensembl chr 8:23,464,860...23,640,513 		JBrowse link
G Cpox coproporphyrinogen oxidase involved_in
acts_upstream_of_or_within		 IEA UniProt GO_REF:0000002 GO_REF:0000043 MGI:1354194 MGI:2152098 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within IMP (PMID:12149233) MGI PMID:12149233 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322 		JBrowse link
G Hmbs hydroxymethylbilane synthase involved_in ISO Uroporphyrin
uroporphyrin I
Urophorphyrin
Uroporphyrin I
Urophorphyrin I
Uroporphyrinogen		 RGD
MGI		 PMID:971328 PMID:994723 PMID:1781034 PMID:3179323 PMID:3702597 More... GO_REF:0000096 MGI:4417868 RGD:2301707 RGD:25330343 RGD:25394583 RGD:25394584 RGD:25440495 RGD:25440497 RGD:26923962 RGD:26923963 RGD:4144783 RGD:4144803 RGD:4144820 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in ISO RGD
MGI		 PMID:3663105 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1599180 NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760 		JBrowse link
G Rsad1 radical S-adenosyl methionine domain containing 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:94,430,624...94,447,690
Ensembl chr11:94,430,624...94,440,081 		JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 acts_upstream_of_or_within IMP (PMID:658175) MGI PMID:658175 NCBI chr15:100,285,779...100,322,090
Ensembl chr15:100,285,779...100,322,953 		JBrowse link
G Spta1 spectrin alpha, erythrocytic 1 acts_upstream_of_or_within IMP (PMID:658175) MGI PMID:658175 NCBI chr 1:174,000,305...174,076,015
Ensembl chr 1:174,000,342...174,076,016 		JBrowse link
G Sptb spectrin beta, erythrocytic acts_upstream_of_or_within IMP (PMID:658175) MGI PMID:658175 NCBI chr12:76,627,262...76,757,321
Ensembl chr12:76,627,262...76,757,321 		JBrowse link
G Urod uroporphyrinogen decarboxylase involved_in ISO RGD
MGI		 PMID:12381387 GO_REF:0000096 MGI:4417868 RGD:4144825 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610 		JBrowse link
G Uros uroporphyrinogen III synthase acts_upstream_of_or_within IMP
IDA		 (PMID:7607680) MGI PMID:7607680 MGI:3620006 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801 		JBrowse link
porphyrin-containing compound catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Urod uroporphyrinogen decarboxylase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610 		JBrowse link
positive regulation of heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP-binding cassette, sub-family B member 7 involved_in IMP
ISO		 (MGI:6695684|PMID:30765471) UniProt
MGI		 PMID:30765471 GO_REF:0000119 MGI:4834177 MGI:6695684 NCBI chr  X:103,324,171...103,457,452
Ensembl chr  X:103,324,263...103,457,462 		JBrowse link
G Slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 involved_in IMP (MGI:6450351|PMID:28495915) ARUK-UCL PMID:28495915 MGI:6450351 NCBI chr 4:117,692,240...117,726,502
Ensembl chr 4:117,691,703...117,732,395 		JBrowse link
protoporphyrinogen IX biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpox coproporphyrinogen oxidase involved_in ISO
IBA		 RGD
GO_Central
MGI		 PMID:3814086 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:4145128 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999 		JBrowse link
G Ireb2 iron responsive element binding protein 2 acts_upstream_of_or_within IMP (PMID:15831703) MGI PMID:15831703 NCBI chr 9:54,769,942...54,819,812
Ensembl chr 9:54,771,073...54,819,814 		JBrowse link
protoporphyrinogen IX metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 acts_upstream_of_or_within IGI (PMID:15931390) MGI PMID:15931390 NCBI chr 5:143,803,586...143,839,535
Ensembl chr 5:143,803,543...143,841,069 		JBrowse link
G Fech ferrochelatase involved_in
acts_upstream_of_or_within		 ISO
IGI		 (PMID:15931390) MGI PMID:15931390 GO_REF:0000119 MGI:4834177 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322 		JBrowse link
G Ppox protoporphyrinogen oxidase involved_in ISO RGD
MGI		 PMID:3663105 GO_REF:0000096 MGI:4417868 RGD:1599180 NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760 		JBrowse link
regulation of heme biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srrd SRR1 domain containing involved_in IMP (MGI:6282940|PMID:28802827) UniProt PMID:28802827 MGI:6282940 NCBI chr 5:112,485,257...112,490,921
Ensembl chr 5:112,485,258...112,490,906 		JBrowse link
G Tmem14a transmembrane protein 14A involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:21,236,609...21,300,391
Ensembl chr 1:21,288,799...21,300,391 		JBrowse link
G Tmem14c transmembrane protein 14C involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:25157825) GO_Central
MGI		 PMID:25157825 GO_REF:0000033 NCBI chr13:41,169,726...41,176,058
Ensembl chr13:41,169,768...41,176,062 		JBrowse link
uroporphyrinogen III biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uros uroporphyrinogen III synthase involved_in ISO
IBA		 RGD
GO_Central
MGI		 PMID:17763925 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:4144811 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801 		JBrowse link
uroporphyrinogen III metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Urod uroporphyrinogen decarboxylase involved_in ISO converts uroporphyrinogen to coproporphyrinogen via hepta-, hexa- and penta-carboxyporphyrinogen RGD
MGI		 PMID:15736160 GO_REF:0000096 MGI:4417868 RGD:2301379 NCBI chr 4:116,847,161...116,851,561
Ensembl chr 4:116,847,162...116,851,610 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28576
    metabolic process 11010
      organic substance metabolic process 10582
        organonitrogen compound metabolic process 5251
          tetrapyrrole metabolic process 54
            porphyrin-containing compound metabolic process 44
              chlorophyll metabolic process + 0
              heme metabolic process + 37
              porphyrin-containing compound biosynthetic process + 31
              porphyrin-containing compound catabolic process + 5
              protoporphyrinogen IX metabolic process + 5
              uroporphyrinogen III metabolic process + 2
paths to the root