Gene: Alas1 (aminolevulinic acid synthase 1)  Mus musculus

Symbol: Alas1
Name: aminolevulinic acid synthase 1
Description: ENCODES a protein that exhibits 5-aminolevulinate synthase activity (ortholog); INVOLVED IN biosynthetic process (inferred); heme biosynthetic process (inferred); metabolic process (inferred); PARTICIPATES IN forkhead class A signaling pathway; heme biosynthetic pathway; glycine, serine and threonine metabolic pathway; ASSOCIATED WITH complete embryonic lethality between implantation and placentation; embryonic growth retardation; ASSOCIATED WITH Diabetes Mellitus, Experimental (ortholog); Hypertension, Pulmonary (ortholog); Porphyrias (ortholog); FOUND IN mitochondrion; cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; Alas-1; Alas-h; ALAS-N; aminolevulinate synthase H; delta-ALA synthase 1; delta-aminolevulinate synthase 1; OTTMUSP00000045078; OTTMUSP00000045079; OTTMUSP00000045080; succinyl-CoA: glycine C-succinyl transferase
Orthologs: Homo sapiens : ALAS1 (aminolevulinate, delta-, synthase 1)  HGNC
Rattus norvegicus : Alas1 (aminolevulinate, delta-, synthase 1)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm389106,233,455 - 106,247,954-NCBI
Mouse cM Map9 -NCBI
Mouse Celera Assembly9105,859,658 - 105,874,969-NCBI
Mouse Genome Assembly Build 379106,135,786 - 106,150,285-NCBI
Mouse Genome Assembly Build 36.19106,136,258 - 106,150,187-NCBI
Mouse Cytogenetic Map9 F1 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Alas1
Entrez Gene
Ensembl Gene
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MGI Report
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RGD Object Information
RGD ID: 68573
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2013-02-27
Status: ACTIVE