| (+)-alpha-tocopherol | multiple interactions | ISO | RGD:68392 | 6480464 | alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of ALAS1 protein] | CTD | PMID:12180188 |
| 1,2,4-trichlorobenzene | increases activity | ISO | RGD:68392 | 6480464 | 1,2,4-trichlorobenzene results in increased activity of ALAS1 protein | CTD | PMID:11996131 PMID:6895089 |
| 1,2,4-trichlorobenzene | increases activity | ISO | RGD:68392 | 6480464 | 1,2,4-trichlorobenzene results in increased activity of ALAS1 protein | CTD | PMID:6895089 PMID:11996131 |
| 1,2,4-trichlorobenzene | multiple interactions | ISO | RGD:68392 | 6480464 | Buthionine Sulfoximine inhibits the reaction [1,2,4-trichlorobenzene results in increased activity of ALAS1 protein] | CTD | PMID:11996131 |
| 17alpha-ethynylestradiol | decreases expression | ISO | RGD:68392 | 6480464 | Ethinyl Estradiol results in decreased expression of ALAS1 mRNA | CTD | PMID:15901920 |
| 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of ALAS1 mRNA | CTD | PMID:17555576 |
| 17beta-estradiol | affects expression | EXP | | 6480464 | Estradiol affects the expression of ALAS1 mRNA | CTD | PMID:15598610 |
| 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of ALAS1 mRNA | CTD | PMID:16684588 |
| 17beta-estradiol | increases expression | ISO | RGD:68572 | 6480464 | Estradiol results in increased expression of ALAS1 mRNA | CTD | PMID:20106945 |
| 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:68392 | 6480464 | [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ALAS1 mRNA | CTD | PMID:16984957 |
| 2,2',4,4',5,5'-hexachlorobiphenyl | increases expression | ISO | RGD:68392 | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of ALAS1 mRNA | CTD | PMID:20959002 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:68572 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ALAS1 mRNA | CTD | PMID:20106945 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:68392 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ALAS1 mRNA | CTD | PMID:16054898 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ALAS1 mRNA | CTD | PMID:21570461 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:68572 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ALAS1 mRNA | CTD | PMID:19692669 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:68392 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ALAS1 mRNA | CTD | PMID:18657588 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:68392 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ALAS1 mRNA | CTD | PMID:16466705 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:68392 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ALAS1 mRNA | CTD | PMID:16466705 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:68572 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ALAS1 mRNA | CTD | PMID:20106945 PMID:19692669 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:68392 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ALAS1 mRNA | CTD | PMID:16054898 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:68572 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ALAS1 mRNA | CTD | PMID:19692669 PMID:20106945 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:68392 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ALAS1 mRNA | CTD | PMID:16054898 more ... |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ALAS1 mRNA | CTD | PMID:18163543 |
| 3,3',4,4',5-pentachlorobiphenyl | multiple interactions | ISO | RGD:68392 | 6480464 | [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ALAS1 mRNA | CTD | PMID:16984957 |
| 3,3',4,4',5-pentachlorobiphenyl | decreases expression | ISO | RGD:68392 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALAS1 mRNA | CTD | PMID:20959002 |
| 3,3',4,4',5-pentachlorobiphenyl | affects expression | ISO | RGD:68572 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl affects the expression of ALAS1 mRNA | CTD | PMID:21703328 |
| 3,3',4,4',5-pentachlorobiphenyl | increases expression | ISO | RGD:68572 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALAS1 mRNA | CTD | PMID:19692669 |
| 3,3',4,4'-tetrachlorobiphenyl | multiple interactions | EXP | | 6480464 | 3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of ALAS1 mRNA] | CTD | PMID:19467301 |
| 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of ALAS1 mRNA | CTD | PMID:18648102 |
| 5-aminolevulinic acid | decreases expression | EXP | | 6480464 | Aminolevulinic Acid results in decreased expression of ALAS1 mRNA | CTD | PMID:22859313 |
| acetylsalicylic acid | increases expression | ISO | RGD:68392 | 6480464 | Aspirin results in increased expression of ALAS1 mRNA | CTD | PMID:12800193 |
| all-trans-retinoic acid | increases expression | ISO | RGD:68572 | 6480464 | Tretinoin results in increased expression of ALAS1 mRNA | CTD | PMID:16140955 PMID:17218384 |
| all-trans-retinoic acid | increases expression | ISO | RGD:68572 | 6480464 | Tretinoin results in increased expression of ALAS1 mRNA | CTD | PMID:15498508 more ... |
| all-trans-retinoic acid | multiple interactions | ISO | RGD:68572 | 6480464 | [Tretinoin co-treated with arsenic trioxide] results in increased expression of ALAS1 mRNA | CTD | PMID:15894607 |
| all-trans-retinoic acid | increases expression | ISO | RGD:68572 | 6480464 | Tretinoin results in increased expression of ALAS1 mRNA | CTD | PMID:15498508 more ... |
| all-trans-retinoic acid | increases expression | ISO | RGD:68572 | 6480464 | Tretinoin results in increased expression of ALAS1 mRNA | CTD | PMID:16140955 more ... |
| all-trans-retinoic acid | increases expression | ISO | RGD:68572 | 6480464 | Tretinoin results in increased expression of ALAS1 mRNA | CTD | PMID:17218384 more ... |
| all-trans-retinoic acid | increases expression | ISO | RGD:68572 | 6480464 | Tretinoin results in increased expression of ALAS1 mRNA | CTD | PMID:15498508 more ... |
| amiodarone | increases expression | ISO | RGD:68572 | 6480464 | Amiodarone results in increased expression of ALAS1 mRNA | CTD | PMID:19774075 |
| benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ALAS1 mRNA | CTD | PMID:21569818 PMID:19770486 |
| benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ALAS1 mRNA | CTD | PMID:19770486 more ... |
| benzo[a]pyrene | increases expression | ISO | RGD:68572 | 6480464 | Benzo(a)pyrene results in increased expression of ALAS1 mRNA | CTD | PMID:20106945 more ... |
| benzo[a]pyrene | increases expression | ISO | RGD:68572 | 6480464 | Benzo(a)pyrene results in increased expression of ALAS1 mRNA | CTD | PMID:20106945 PMID:21632981 |
| benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ALAS1 mRNA | CTD | PMID:19770486 |
| benzo[a]pyrene | increases expression | ISO | RGD:68572 | 6480464 | Benzo(a)pyrene results in increased expression of ALAS1 mRNA | CTD | PMID:20106945 |
| benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ALAS1 mRNA | CTD | PMID:19770486 PMID:21569818 |
| bis(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in increased expression of ALAS1 mRNA | CTD | PMID:19245819 |
| bisphenol A | increases expression | ISO | RGD:68392 | 6480464 | bisphenol A results in increased expression of ALAS1 mRNA | CTD | PMID:17010207 |
| bucladesine | multiple interactions | EXP | | 6480464 | [NFE2L2 gene mutant form results in increased susceptibility to Bucladesine] which results in increased expression of ALAS1 mRNA | CTD | PMID:22859313 |
| butyric acid | increases expression | ISO | RGD:68392 | 6480464 | Butyric Acid results in increased expression of ALAS1 mRNA | CTD | PMID:12800193 |
| cefaloridine | increases expression | ISO | RGD:68392 | 6480464 | Cephaloridine results in increased expression of ALAS1 mRNA | CTD | PMID:18500788 |
| chlorobenzene | increases activity | ISO | RGD:68392 | 6480464 | chlorobenzene results in increased activity of ALAS1 protein | CTD | PMID:6895089 |
| chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of ALAS1 mRNA | CTD | PMID:23125180 |
| clofibrate | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of ALAS1 mRNA; more ... | CTD | PMID:17585979 |
| clofibrate | increases expression | ISO | RGD:68392 | 6480464 | Clofibrate results in increased expression of ALAS1 mRNA | CTD | PMID:11328961 PMID:12851107 |
| clofibrate | increases expression | ISO | RGD:68392 | 6480464 | Clofibrate results in increased expression of ALAS1 mRNA | CTD | PMID:12851107 PMID:11328961 |
| clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of ALAS1 mRNA | CTD | PMID:17585979 |
| cobalt dichloride | affects expression | ISO | RGD:68572 | 6480464 | cobaltous chloride affects the expression of ALAS1 mRNA alternative form | CTD | PMID:19320972 |
| copper atom | decreases expression | EXP | | 6480464 | Copper results in decreased expression of ALAS1 mRNA | CTD | PMID:17205981 |
| copper(0) | decreases expression | EXP | | 6480464 | Copper results in decreased expression of ALAS1 mRNA | CTD | PMID:17205981 |
| copper(2+) sulfate | increases expression | ISO | RGD:68572 | 6480464 | Copper Sulfate results in increased expression of ALAS1 mRNA | CTD | PMID:19549813 |
| curcumin | increases expression | ISO | RGD:68392 | 6480464 | Curcumin results in increased expression of ALAS1 mRNA | CTD | PMID:18299980 |
| cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of ALAS1 mRNA | CTD | PMID:19770486 |
| diarsenic trioxide | increases expression | ISO | RGD:68572 | 6480464 | arsenic trioxide results in increased expression of ALAS1 mRNA | CTD | PMID:15725085 |
| diarsenic trioxide | multiple interactions | ISO | RGD:68572 | 6480464 | [Tretinoin co-treated with arsenic trioxide] results in increased expression of ALAS1 mRNA | CTD | PMID:15894607 |
| dibutyl phthalate | decreases expression | ISO | RGD:68392 | 6480464 | Dibutyl Phthalate results in decreased expression of ALAS1 mRNA | CTD | PMID:21266533 |
| dibutyl phthalate | decreases expression | ISO | RGD:68392 | 6480464 | Dibutyl Phthalate results in decreased expression of ALAS1 mRNA | CTD | PMID:17379624 PMID:21266533 |
| dibutyl phthalate | increases expression | ISO | RGD:68392 | 6480464 | Dibutyl Phthalate results in increased expression of ALAS1 mRNA | CTD | PMID:21266533 |
| doxorubicin | decreases expression | ISO | RGD:68392 | 6480464 | Doxorubicin results in decreased expression of ALAS1 mRNA | CTD | PMID:19915844 |
| elemental selenium | increases expression | ISO | RGD:68572 | 6480464 | Selenium results in increased expression of ALAS1 mRNA | CTD | PMID:19244175 |
| ethanol | multiple interactions | ISO | RGD:68392 | 6480464 | [Fish Oils co-treated with Ethanol] results in increased expression of ALAS1 mRNA | CTD | PMID:17347304 |
| ferroheme b | decreases expression | ISO | RGD:68572 | 6480464 | Heme results in decreased expression of ALAS1 protein | CTD | PMID:21659532 |
| ferroheme b | multiple interactions | ISO | RGD:68572 | 6480464 | Protease Inhibitors inhibits the reaction [Heme results in decreased expression of ALAS1 protein]; more ... | CTD | PMID:21659532 |
| genistein | increases expression | ISO | RGD:68392 | 6480464 | Genistein results in increased expression of ALAS1 mRNA | CTD | PMID:17010207 |
| griseofulvin | increases expression | EXP | | 6480464 | Griseofulvin results in increased expression of ALAS1 mRNA | CTD | PMID:15793285 |
| griseofulvin | affects expression | EXP | | 6480464 | Griseofulvin affects the expression of ALAS1 mRNA | CTD | PMID:12735108 |
| isotretinoin | decreases expression | ISO | RGD:68572 | 6480464 | Isotretinoin results in decreased expression of ALAS1 mRNA | CTD | PMID:20436886 |
| methotrexate | affects expression | EXP | | 6480464 | Methotrexate affects the expression of ALAS1 mRNA | CTD | PMID:18502557 |
| methyl methacrylate | increases expression | EXP | | 6480464 | Methylmethacrylate results in increased expression of ALAS1 mRNA | CTD | PMID:16916219 |
| nickel atom | decreases expression | EXP | | 6480464 | Nickel results in decreased expression of ALAS1 mRNA | CTD | PMID:12540486 |
| paracetamol | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of ALAS1 mRNA; more ... | CTD | PMID:17585979 |
| paracetamol | increases expression | ISO | RGD:68572 | 6480464 | Acetaminophen results in increased expression of ALAS1 mRNA | CTD | PMID:21420995 |
| paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of ALAS1 mRNA | CTD | PMID:17562736 PMID:15606129 |
| paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of ALAS1 mRNA | CTD | PMID:15606129 PMID:17562736 |
| paracetamol | affects expression | ISO | RGD:68392 | 6480464 | Acetaminophen affects the expression of ALAS1 mRNA | CTD | PMID:17366322 |
| paraquat | multiple interactions | ISO | RGD:68392 | 6480464 | alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of ALAS1 protein] | CTD | PMID:12180188 |
| paraquat | increases activity | ISO | RGD:68392 | 6480464 | Paraquat results in increased activity of ALAS1 protein | CTD | PMID:12180188 |
| perfluorooctanoic acid | increases expression | ISO | RGD:68392 | 6480464 | perfluorooctanoic acid results in increased expression of ALAS1 mRNA | CTD | PMID:19162173 |
| phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of ALAS1 mRNA | CTD | PMID:19270015 |
| phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of ALAS1 mRNA | CTD | PMID:19270015 more ... |
| phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of ALAS1 mRNA | CTD | PMID:19270015 PMID:22859313 |
| phenobarbital | affects expression | ISO | RGD:68572 | 6480464 | Phenobarbital affects the expression of ALAS1 mRNA | CTD | PMID:19159669 |
| phenobarbital | increases expression | ISO | RGD:68572 | 6480464 | Phenobarbital results in increased expression of ALAS1 mRNA | CTD | PMID:19084549 |
| phenobarbital | increases expression | ISO | RGD:68392 | 6480464 | Phenobarbital results in increased expression of ALAS1 mRNA | CTD | PMID:19162173 |
| phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of ALAS1 mRNA | CTD | PMID:19270015 |
| pirinixic acid | multiple interactions | ISO | RGD:68572 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ALAS1 mRNA | CTD | PMID:19710929 |
| pirinixic acid | increases expression | ISO | RGD:68392 | 6480464 | pirinixic acid results in increased expression of ALAS1 mRNA | CTD | PMID:19162173 |
| pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of ALAS1 mRNA | CTD | PMID:18445702 |
| pregnenolone 16alpha-carbonitrile | increases expression | ISO | RGD:68392 | 6480464 | Pregnenolone Carbonitrile results in increased expression of ALAS1 mRNA | CTD | PMID:19162173 |
| propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of ALAS1 mRNA | CTD | PMID:21278054 |
| pyridine | increases activity | ISO | RGD:68392 | 6480464 | pyridine results in increased activity of ALAS1 protein | CTD | PMID:10413312 |
| quercetin | increases expression | ISO | RGD:68572 | 6480464 | Quercetin results in increased expression of ALAS1 mRNA | CTD | PMID:21632981 |
| S-butyl-DL-homocysteine (S,R)-sulfoximine | multiple interactions | ISO | RGD:68392 | 6480464 | Buthionine Sulfoximine inhibits the reaction [1,2,4-trichlorobenzene results in increased activity of ALAS1 protein] | CTD | PMID:11996131 |
| selenium atom | increases expression | ISO | RGD:68572 | 6480464 | Selenium results in increased expression of ALAS1 mRNA | CTD | PMID:19244175 |
| sevoflurane | affects expression | ISO | RGD:68392 | 6480464 | sevoflurane affects the expression of ALAS1 mRNA | CTD | PMID:15967596 |
| streptozocin | decreases expression | ISO | RGD:68392 | 6480464 | Streptozocin results in decreased expression of ALAS1 mRNA | CTD | PMID:16684804 |
| streptozocin | multiple interactions | ISO | RGD:68392 | 6480464 | vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of ALAS1 mRNA] | CTD | PMID:16684804 |
| tamibarotene | increases expression | ISO | RGD:68572 | 6480464 | Am 80 results in increased expression of ALAS1 mRNA; more ... | CTD | PMID:15498508 |
| tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of ALAS1 mRNA | CTD | PMID:20937368 |
| tert-butyl hydroperoxide | decreases expression | ISO | RGD:68572 | 6480464 | tert-Butylhydroperoxide results in decreased expression of ALAS1 protein | CTD | PMID:21659532 |
| testosterone | increases expression | EXP | | 6480464 | Testosterone results in increased expression of ALAS1 mRNA | CTD | PMID:20403060 |
| tetrachloromethane | affects expression | ISO | RGD:68392 | 6480464 | Carbon Tetrachloride affects the expression of ALAS1 mRNA | CTD | PMID:16239168 |
| valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of ALAS1 mRNA | CTD | PMID:17292431 |
| vanadyl sulfate | multiple interactions | ISO | RGD:68392 | 6480464 | vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of ALAS1 mRNA] | CTD | PMID:16684804 |
| zinc atom | decreases expression | ISO | RGD:68392 | 6480464 | Zinc deficiency results in decreased expression of ALAS1 mRNA | CTD | PMID:12672911 |
| zinc(0) | decreases expression | ISO | RGD:68392 | 6480464 | Zinc deficiency results in decreased expression of ALAS1 mRNA | CTD | PMID:12672911 |