RGD Reference Report - Pteridine regulation of inhibition of hepatic uroporphyrinogen L synthetase activity by lead chloride. - Rat Genome Database

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Pteridine regulation of inhibition of hepatic uroporphyrinogen L synthetase activity by lead chloride.

Authors: Piper, W N  Van Lier, B L 
Citation: Piper WN and Van Lier BL, Mol Pharmacol. 1977 Nov;13(6):1126-35.
RGD ID: 26884337
Pubmed: PMID:593266   (View Abstract at PubMed)

Abstract for this paper unavailable

Gene-Chemical Interaction Annotations    Click to see Annotation Detail View
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
dihydrofolic acid increases activityISOHmbs (Rattus norvegicus)26884337; 26884337Dihydrofolic acid increases activity of purified Hmbs proteinRGD 
dihydrofolic acid increases activityEXP 26884337Dihydrofolic acid increases activity of purified Hmbs proteinRGD 

Gene Ontology Annotations    Click to see Annotation Detail View

Biological Process
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
porphyrin-containing compound metabolic process  IDA 26884337Uroporphyrinogen RGD 

Molecular Function
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
hydroxymethylbilane synthase activity  IDA 26884337 RGD 

Molecular Pathway Annotations    Click to see Annotation Detail View

RGD Manual Annotations

TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
heme biosynthetic pathway   ISOHmbs (Rattus norvegicus)26884337; 26884337 RGD 
heme biosynthetic pathway   IDA 26884337 RGD 
Objects Annotated

Genes (Rattus norvegicus)
Hmbs  (hydroxymethylbilane synthase)

Genes (Mus musculus)
Hmbs  (hydroxymethylbilane synthase)

Genes (Homo sapiens)
HMBS  (hydroxymethylbilane synthase)


Additional Information