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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Churg-Strauss syndrome
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Accession:DOID:3049 term browser browse the term
Definition:A vasculitits that is systemic vasculitis realized as blood vessel inflammation and has_symptom asthma along with hay fever, rash and gastrointestinal bleeding. (DO)
Synonyms:exact_synonym: Allergic Angiitis;   Allergic Angiitis and Granulomatosis;   Allergic Granulomatoses;   Allergic Granulomatosis;   Allergic Granulomatous Angiitides;   Allergic Granulomatous Angiitis;   Allergic Granulomatous and Angiitis;   Churg-Strauss Vasculitis;   Eosinophilic Granulomatous Vasculitides;   allergic angiitides;   allergic granulomatosis angiitis;   eosinophilic granulomatous vasculitis
 primary_id: MESH:D015267
 xref: EFO:0007208;   ICD10CM:M30.1;   NCI:C34481
For additional species annotation, visit the Alliance of Genome Resources.


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Churg-Strauss syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL26 C-C motif chemokine ligand 26 IEP protein:increased expression:serum (human) RGD PMID:21266446 RGD:11081158 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896 		JBrowse link
G GDNF glial cell derived neurotrophic factor IEP RGD PMID:9853108 RGD:6218983 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G GFRA1 GDNF family receptor alpha 1 IEP RGD PMID:9853108 RGD:6218983 NCBI chr10:116,056,925...116,274,705
Ensembl chr10:116,056,925...116,276,803 		JBrowse link
G IL5 interleukin 5 severity IEP RGD PMID:22772323 RGD:6892720 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 IEP RGD PMID:22772323 RGD:6892720 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G VTN vitronectin IDA RGD PMID:12126637 RGD:1580817 NCBI chr17:28,367,284...28,370,307
Ensembl chr17:28,367,284...28,373,091 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 35753
    Pathological Conditions, Signs and Symptoms 21489
      Pathologic Processes 13190
        Granuloma 36
          Churg-Strauss syndrome 6
Path 2
Term Annotations click to browse term
  disease 35753
    disease of anatomical entity 32492
      Immune & Inflammatory Diseases 6739
        immune system disease 5902
          Immunoproliferative Disorders 1359
            lymphoproliferative syndrome 1349
              Granuloma 36
                Churg-Strauss syndrome 6
paths to the root