RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Contrast-Induced Nephropathy
Accession: DOID:9005666
browse the term
Definition: Impairment of renal function within 48-72 hours of intravenous contrast administration.
Synonyms: exact_synonym: CIN; contrast nephropathy
related_synonym: hospital-acquired acute kidney injury
primary_id: RDO:9000018
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Casp12
caspase 12
treatment
IEP
RGD
PMID:27781957
RGD:13782262
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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Casp3
caspase 3
treatment
IDA
RGD
PMID:27781957
RGD:13782262
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Crp
C-reactive protein
ISO
associated with coronary disease;
RGD
PMID:23102387
RGD:6909166
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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Ddit3
DNA-damage inducible transcript 3
treatment
IEP
RGD
PMID:27781957
RGD:13782262
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ece1
endothelin converting enzyme 1
IEP
mRNA,protein:increased expression:kidney medulla
RGD
PMID:18385664
RGD:7243946
NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
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Havcr1
hepatitis A virus cellular receptor 1
IEP
protein:increased expression:urine:
RGD
PMID:23335628
RGD:7245471
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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Hspa5
heat shock protein family A (Hsp70) member 5
treatment
IEP
RGD
PMID:27781957
RGD:13782262
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Il1b
interleukin 1 beta
IDA
associated with Diabetes Mellitus, Experimental
RGD
PMID:22094062
RGD:7175334
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Lcn2
lipocalin 2
IEP
protein:increased expression:urine: associated with Diabetes Mellitus, Experimental; protein:increased expression:urine
RGD
PMID:23335628 PMID:23085980
RGD:7245471 , RGD:7245484
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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Mapk8
mitogen-activated protein kinase 8
treatment
IDA
RGD
PMID:27781957
RGD:13782262
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mir188
microRNA 188
ISO IEP
RNA:increased expression:plasma RNA:increased expression:plasma, kidney
RGD
PMID:27528406 PMID:27528406
RGD:35673289 , RGD:35673289
NCBI chr X:15,247,715...15,247,794
Ensembl chr X:15,247,715...15,247,794
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Mir30a
microRNA 30a
ISO IEP
RNA:increased expression:plasma
RGD
PMID:27528406 PMID:27528406
RGD:35673289 , RGD:35673289
NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
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Mir30e
microRNA 30e
ISO IEP
RNA:increased expression:plasma
RGD
PMID:27528406 PMID:27528406
RGD:35673289 , RGD:35673289
NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
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Mpo
myeloperoxidase
IDA
RGD
PMID:20722568
RGD:6909183
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Nppa
natriuretic peptide A
ISO
RGD
PMID:19298916
RGD:7247719
NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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Nppb
natriuretic peptide B
ISO
associated with Heart Failure
RGD
PMID:20438292
RGD:7248591
NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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