The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A xanthine that is 7H-xanthine bearing (4-methylquinazolin-2-yl)methyl, methyl, but-2-yn-1-yl and 3-aminopiperidin-1-yl substituents at positions 1, 3, 7 and 8 respectively (the R-enantiomer). Used for treatment of type II diabetes.
indole-3-carbinol promotes the reaction [Linagliptin inhibits the reaction [letrozole results in decreased expression of HMOX1 protein]]; Linagliptin inhibits the reaction [letrozole results in decreased expression of HMOX1 protein]; Linagliptin promotes the reaction [indole-3-carbinol inhibits the reaction [letrozole results in decreased expression of HMOX1 protein]]
indole-3-carbinol promotes the reaction [Linagliptin inhibits the reaction [Letrozole results in increased expression of IL10 protein]]; Linagliptin inhibits the reaction [Acetic Acid results in decreased expression of IL10 protein]; Linagliptin inhibits the reaction [Letrozole results in increased expression of IL10 protein]; Linagliptin promotes the reaction [indole-3-carbinol inhibits the reaction [Letrozole results in increased expression of IL10 protein]]
indole-3-carbinol promotes the reaction [Linagliptin inhibits the reaction [Letrozole results in increased expression of INS1 protein]]; Linagliptin inhibits the reaction [Letrozole results in increased expression of INS1 protein]; Linagliptin promotes the reaction [indole-3-carbinol inhibits the reaction [Letrozole results in increased expression of INS1 protein]]
Linagliptin inhibits the reaction [Cuprizone results in increased expression of JAK2 protein modified form] Linagliptin inhibits the reaction [Acetic Acid results in increased phosphorylation of JAK2 protein]
indole-3-carbinol promotes the reaction [Linagliptin inhibits the reaction [letrozole results in increased expression of LHB protein]]; Linagliptin inhibits the reaction [letrozole results in increased expression of LHB protein]; Linagliptin promotes the reaction [indole-3-carbinol inhibits the reaction [letrozole results in increased expression of LHB protein]]
indole-3-carbinol promotes the reaction [Linagliptin inhibits the reaction [letrozole results in decreased expression of NFE2L2 protein]]; Linagliptin inhibits the reaction [letrozole results in decreased expression of NFE2L2 protein]; Linagliptin promotes the reaction [indole-3-carbinol inhibits the reaction [letrozole results in decreased expression of NFE2L2 protein]]
Linagliptin inhibits the reaction [Cisplatin results in decreased expression of PPARGC1A protein] Linagliptin inhibits the reaction [Acetic Acid results in decreased expression of PPARGC1A mRNA]
indole-3-carbinol promotes the reaction [Linagliptin inhibits the reaction [Letrozole affects the localization of RELA protein]]; Linagliptin inhibits the reaction [Acetic Acid results in increased expression of RELA protein]; Linagliptin inhibits the reaction [Letrozole affects the localization of RELA protein]; Linagliptin promotes the reaction [indole-3-carbinol inhibits the reaction [Letrozole affects the localization of RELA protein]] Linagliptin inhibits the reaction [Cuprizone results in increased expression of RELA protein]
Linagliptin inhibits the reaction [Cuprizone results in decreased expression of SIRT1 mRNA] Linagliptin inhibits the reaction [Acetic Acid results in decreased expression of SIRT1 mRNA]
Linagliptin inhibits the reaction [Cuprizone results in increased expression of STAT3 protein modified form] Linagliptin inhibits the reaction [Acetic Acid results in increased phosphorylation of STAT3 protein]
indole-3-carbinol promotes the reaction [Linagliptin inhibits the reaction [letrozole results in increased expression of TGFB1 protein]]; Linagliptin inhibits the reaction [letrozole results in increased expression of TGFB1 protein]; Linagliptin promotes the reaction [indole-3-carbinol inhibits the reaction [letrozole results in increased expression of TGFB1 protein]]
indole-3-carbinol promotes the reaction [Linagliptin inhibits the reaction [Letrozole results in increased expression of TNF protein]]; Linagliptin inhibits the reaction [Acetic Acid results in increased expression of TNF protein]; Linagliptin inhibits the reaction [Letrozole results in increased expression of TNF protein]; Linagliptin promotes the reaction [indole-3-carbinol inhibits the reaction [Letrozole results in increased expression of TNF protein]] Linagliptin inhibits the reaction [Cuprizone results in increased expression of TNF protein]
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