Gene: Plp1 (proteolipid protein 1)  Rattus norvegicus

Symbol: Plp1
Name: proteolipid protein 1
Description: ENCODES a protein that exhibits structural constituent of myelin sheath; structural molecule activity; INVOLVED IN axon ensheathment; glial cell differentiation; integrin-mediated signaling pathway; ASSOCIATED WITH premature death; tremors; ASSOCIATED WITH Seizures; Pelizaeus-Merzbacher Disease (ortholog); Spastic paraplegia 2, X-linked (ortholog); FOUND IN myelin sheath (ortholog); INTERACTS WITH alachlor; all-trans-retinoic acid; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: lipophilin; myelin proteolipid protein; Plp; proteolipid protein; proteolipid protein (myelin); proteolipid protein (myelin) 1; Proteolipid protein (Pelizaeus-Merzbacher disease spastic paraplegia 2 uncomplicated); Proteolipid protein (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated)
Orthologs: Homo sapiens : PLP1 (proteolipid protein 1)  HGNC
Mus musculus : Plp1 (proteolipid protein (myelin) 1)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic MapXq35 NCBI
RGSC Genome Assembly v5.0X107,379,831 - 107,394,881+NCBI
RGSC Genome Assembly v3.4X124,488,627 - 124,503,639+NCBI
Rat Celera AssemblyX101,020,110 - 101,035,276+NCBI
Genome Assembly 3.1X124,562,059 - 124,577,072+NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)
Related Rat Strains

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Plp1
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RGD Object Information
RGD ID: 3354
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE