Akt nuclear targets

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Akt nuclear targets

Phosphorylation by Akt kinases leads to activation/deactivation of target genes, promoting the downstream effects of the PI3K-Akt pathway. Some of the nuclear targets of Akt are listed with aliases in parentheses, full names and links to gene report pages:

Foxo4 (Afx) – forkhead box O4
Foxo1 (Fkhr) – forkhead box O1
Foxo3 (Fkhrl1) – forkhead box O3
Gsk3b – glycogen synthase kinase 3 beta

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.