Pde1b (phosphodiesterase 1B) - Rat Genome Database

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Gene: Pde1b (phosphodiesterase 1B) Rattus norvegicus
Analyze
Symbol: Pde1b
Name: phosphodiesterase 1B
RGD ID: 3278
Description: Enables 3',5'-cyclic-AMP phosphodiesterase activity. Predicted to be involved in cellular response to cytokine stimulus; monocyte differentiation; and negative regulation of cAMP/PKA signal transduction. Predicted to act upstream of with a positive effect on dopamine catabolic process. Predicted to act upstream of or within several processes, including response to amphetamine; serotonin metabolic process; and visual learning. Located in neuronal cell body. Biomarker of Parkinsonism. Orthologous to human PDE1B (phosphodiesterase 1B); PARTICIPATES IN protein kinase A (PKA) signaling pathway; calcium/calcium-mediated signaling pathway; purine metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 63 kDa Cam-PDE; anti-oxidant protein 2; Aop2; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; cam-PDE 1B; cyclic nucleotide phosphodiesterase (CaM-PDE); dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; Pde1b1; phosphodiesterase 1B, Ca2+calmodulin dependent; phosphodiesterase 1B, calmodulin-dependent; phosphodiesterase 1B1 Ca2+-calmodulin dependent 63 kDa; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase IB calmodulin-dependent; phosphodiesterase IB, calmodulin-dependent
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87136,505,834 - 136,533,034 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7136,505,689 - 136,533,033 (+)EnsemblGRCr8
mRatBN7.27134,627,378 - 134,654,581 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7134,627,322 - 134,654,580 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7136,382,888 - 136,409,313 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07138,612,263 - 138,638,684 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07138,598,329 - 138,624,285 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07145,117,951 - 145,147,711 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7145,117,951 - 145,145,376 (+)Ensemblrn6Rnor6.0
Rnor_5.07142,899,029 - 142,925,733 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47142,401,489 - 142,427,626 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7131,051,310 - 131,077,552 (+)NCBICelera
RGSC_v3.17142,481,677 - 142,507,815 (+)NCBI
Cytogenetic Map7q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA,ISO,ISS)
neuronal cell body  (IBA,IDA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Conti M and Beavo J, Annu Rev Biochem. 2007;76:481-511.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. A polymerase chain reaction strategy to identify and clone cyclic nucleotide phosphodiesterase cDNAs. Molecular cloning of the cDNA encoding the 63-kDa calmodulin-dependent phosphodiesterase. Repaske DR, etal., J Biol Chem 1992 Sep 15;267(26):18683-8.
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Down-regulation of nitrergic transmission in the rat striatum after chronic nigrostriatal deafferentation. Sancesario G, etal., Eur J Neurosci. 2004 Aug;20(4):989-1000.
12. Gene expression and protein localization of calmodulin-dependent phosphodiesterase in adult rat retina. Santone R, etal., J Neurosci Res. 2006 Oct;84(5):1020-6.
Additional References at PubMed
PMID:12077213   PMID:14687666   PMID:17010100   PMID:17559891   PMID:19292454   PMID:33444639  


Genomics

Comparative Map Data
Pde1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87136,505,834 - 136,533,034 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7136,505,689 - 136,533,033 (+)EnsemblGRCr8
mRatBN7.27134,627,378 - 134,654,581 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7134,627,322 - 134,654,580 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7136,382,888 - 136,409,313 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07138,612,263 - 138,638,684 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07138,598,329 - 138,624,285 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07145,117,951 - 145,147,711 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7145,117,951 - 145,145,376 (+)Ensemblrn6Rnor6.0
Rnor_5.07142,899,029 - 142,925,733 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47142,401,489 - 142,427,626 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7131,051,310 - 131,077,552 (+)NCBICelera
RGSC_v3.17142,481,677 - 142,507,815 (+)NCBI
Cytogenetic Map7q36NCBI
PDE1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381254,549,601 - 54,579,239 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1254,549,601 - 54,579,241 (+)Ensemblhg38GRCh38
GRCh371254,943,385 - 54,973,023 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361253,229,671 - 53,259,290 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341253,229,670 - 53,259,290NCBI
Celera1254,595,042 - 54,624,893 (+)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1251,981,948 - 52,011,831 (+)NCBIHuRef
CHM1_11254,909,885 - 54,939,730 (+)NCBICHM1_1
T2T-CHM13v2.01254,516,175 - 54,545,790 (+)NCBIT2T-CHM13v2.0
Pde1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915103,411,461 - 103,438,483 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15103,411,461 - 103,438,479 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3815103,503,034 - 103,530,056 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15103,503,034 - 103,530,052 (+)Ensemblmm10GRCm38
MGSCv3715103,333,729 - 103,360,483 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3615103,331,333 - 103,358,086 (+)NCBIMGSCv36mm8
Celera15105,661,285 - 105,688,050 (+)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1558.99NCBI
Pde1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554581,791,090 - 1,821,813 (+)Ensembl
ChiLan1.0NW_0049554581,791,090 - 1,819,261 (+)NCBIChiLan1.0ChiLan1.0
PDE1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21039,595,568 - 39,625,258 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11239,592,337 - 39,622,028 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01234,167,801 - 34,198,049 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11234,896,362 - 34,926,223 (-)NCBIPanPan1.1PanPan1.1panPan2
PDE1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.127772,741 - 800,967 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl27772,056 - 800,375 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2745,453,293 - 45,480,837 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.027771,740 - 798,788 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl27771,072 - 798,938 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.127763,412 - 791,180 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.027771,568 - 799,618 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02745,857,507 - 45,884,981 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pde1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494561,398,566 - 61,425,617 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651211,739,213 - 11,768,190 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493651211,739,219 - 11,766,264 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDE1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl519,725,415 - 19,752,888 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1519,725,346 - 19,752,892 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2520,582,610 - 20,612,210 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PDE1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11150,664,801 - 50,694,887 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1150,664,844 - 50,692,971 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037195,341,788 - 195,371,575 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pde1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249042,580,322 - 2,607,961 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249042,580,055 - 2,607,961 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pde1b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11259,558,381 - 259,585,489 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:181
Count of miRNA genes:114
Interacting mature miRNAs:143
Transcripts:ENSRNOT00000055272
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7121393075137014596Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)7132099939137014596Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7135371291137014596Rat

Markers in Region
RH127463  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27134,654,201 - 134,654,408 (+)MAPPERmRatBN7.2
Rnor_6.07145,146,104 - 145,146,310NCBIRnor6.0
Rnor_5.07142,925,354 - 142,925,560UniSTSRnor5.0
RGSC_v3.47142,428,354 - 142,428,560UniSTSRGSC3.4
Celera7131,078,280 - 131,078,486UniSTS
RH 3.4 Map71063.5UniSTS
Cytogenetic Map7q36UniSTS
BE120220  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27134,648,502 - 134,648,665 (+)MAPPERmRatBN7.2
Rnor_6.07145,140,408 - 145,140,570NCBIRnor6.0
Rnor_5.07142,919,658 - 142,919,820UniSTSRnor5.0
RGSC_v3.47142,422,658 - 142,422,820UniSTSRGSC3.4
Celera7131,072,584 - 131,072,746UniSTS
RH 3.4 Map71063.5UniSTS
Cytogenetic Map7q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 67 162 89 88 57 81 57 6 341 181 11 135 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000055272   ⟹   ENSRNOP00000052147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7136,505,689 - 136,533,030 (+)Ensembl
mRatBN7.2 Ensembl7134,627,322 - 134,654,580 (+)Ensembl
Rnor_6.0 Ensembl7145,117,951 - 145,145,376 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099138   ⟹   ENSRNOP00000095772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7136,517,503 - 136,533,033 (+)Ensembl
mRatBN7.2 Ensembl7134,639,118 - 134,654,580 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000143728   ⟹   ENSRNOP00000101163
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7136,518,781 - 136,533,033 (+)Ensembl
RefSeq Acc Id: NM_022710   ⟹   NP_073201
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87136,505,834 - 136,531,927 (+)NCBI
mRatBN7.27134,627,378 - 134,653,474 (+)NCBI
Rnor_6.07145,117,951 - 145,145,376 (+)NCBI
Rnor_5.07142,899,029 - 142,925,733 (+)NCBI
RGSC_v3.47142,401,489 - 142,427,626 (+)RGD
Celera7131,051,310 - 131,077,552 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242386   ⟹   XP_006242448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87136,517,400 - 136,533,034 (+)NCBI
mRatBN7.27134,638,954 - 134,654,581 (+)NCBI
Rnor_6.07145,129,119 - 145,147,711 (+)NCBI
Rnor_5.07142,899,029 - 142,925,733 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063263129   ⟹   XP_063119199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87136,516,681 - 136,533,034 (+)NCBI
RefSeq Acc Id: NP_073201   ⟸   NM_022710
- UniProtKB: Q548L3 (UniProtKB/Swiss-Prot),   Q01066 (UniProtKB/Swiss-Prot),   A6KD12 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242448   ⟸   XM_006242386
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ANV0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000052147   ⟸   ENSRNOT00000055272
Ensembl Acc Id: ENSRNOP00000095772   ⟸   ENSRNOT00000099138
RefSeq Acc Id: XP_063119199   ⟸   XM_063263129
- Peptide Label: isoform X2
- UniProtKB: A6KD13 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101163   ⟸   ENSRNOT00000143728
Protein Domains
PDE1 N-terminal   PDEase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q01066-F1-model_v2 AlphaFold Q01066 1-535 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695719
Promoter ID:EPDNEW_R6244
Type:multiple initiation site
Name:Pde1b_1
Description:phosphodiesterase 1B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07145,117,856 - 145,117,916EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3278 AgrOrtholog
BioCyc Gene G2FUF-31868 BioCyc
Ensembl Genes ENSRNOG00000036828 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000055272 ENTREZGENE
  ENSRNOT00000055272.4 UniProtKB/Swiss-Prot
  ENSRNOT00000099138 ENTREZGENE
  ENSRNOT00000143728 ENTREZGENE
Gene3D-CATH 1.10.1300.10 UniProtKB/Swiss-Prot
InterPro HD/PDEase_dom UniProtKB/Swiss-Prot
  PDEase UniProtKB/Swiss-Prot
  PDEase_catalytic_dom UniProtKB/Swiss-Prot
  PDEase_catalytic_dom_sf UniProtKB/Swiss-Prot
  PDEase_CS UniProtKB/Swiss-Prot
  PDEase_N UniProtKB/Swiss-Prot
KEGG Report rno:29691 UniProtKB/Swiss-Prot
NCBI Gene 29691 ENTREZGENE
PANTHER CYCLIC NUCLEOTIDE PHOSPHODIESTERASE UniProtKB/Swiss-Prot
Pfam PDEase_I UniProtKB/Swiss-Prot
  PDEase_I_N UniProtKB/Swiss-Prot
PhenoGen Pde1b PhenoGen
PRINTS PDIESTERASE1 UniProtKB/Swiss-Prot
PROSITE PDEASE_I_1 UniProtKB/Swiss-Prot
  PDEASE_I_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000036828 RatGTEx
SMART HDc UniProtKB/Swiss-Prot
Superfamily-SCOP HD-domain/PDEase-like UniProtKB/Swiss-Prot
UniProt A0A8I6ANV0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LJU9_RAT UniProtKB/TrEMBL
  A6KD12 ENTREZGENE, UniProtKB/TrEMBL
  A6KD13 ENTREZGENE, UniProtKB/TrEMBL
  PDE1B_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q548L3 ENTREZGENE
  Q99MN4_RAT UniProtKB/TrEMBL
  Q99MN5_RAT UniProtKB/TrEMBL
UniProt Secondary Q548L3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-30 Pde1b  phosphodiesterase 1B  Pde1b  phosphodiesterase 1B, calmodulin-dependent  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-08-29 Pde1b  phosphodiesterase 1B, calmodulin-dependent  Pde1b  phosphodiesterase 1B, Ca2+calmodulin dependent  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Pde1b  phosphodiesterase 1B, Ca2+calmodulin dependent    phosphodiesterase 1B  Name updated 1299863 APPROVED
2002-06-10 Pde1b  phosphodiesterase 1B      Name updated 70584 APPROVED