Mir375 (microRNA 375) - Rat Genome Database

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Gene: Mir375 (microRNA 375) Mus musculus
Analyze
Symbol: Mir375
Name: microRNA 375
RGD ID: 1607621
MGI Page MGI
Description: Acts upstream of or within type B pancreatic cell development. Predicted to be part of RISC complex. Is expressed in several structures, including brain; connective tissue; liver; pancreas; and skeleton. Orthologous to human MIR375 (microRNA 375).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-375; Mirn; Mirn375; mmu-mir-3; mmu-mir-375
RGD Orthologs
Human
Rat
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,939,817 - 74,939,880 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,939,817 - 74,939,880 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38174,900,658 - 74,900,721 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,900,658 - 74,900,721 (-)Ensemblmm10GRCm38
MGSCv37174,947,232 - 74,947,295 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera175,455,688 - 75,455,751 (-)NCBICelera
Cytogenetic Map1C4NCBI
cM Map138.54NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IEA)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. miR-375 inhibits Helicobacter pylori-induced gastric carcinogenesis by blocking JAK2-STAT3 signaling. Miao L, etal., Cancer Immunol Immunother. 2014 Jul;63(7):699-711. doi: 10.1007/s00262-014-1550-y. Epub 2014 Apr 10.
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15538371   PMID:15806104   PMID:16381832   PMID:16943360   PMID:17369397   PMID:17604727   PMID:17804764   PMID:18184563   PMID:18591395   PMID:19289822   PMID:20215419   PMID:20221699  
PMID:20224724   PMID:20413612   PMID:20584986   PMID:20807761   PMID:21037258   PMID:21267068   PMID:21291493   PMID:21822254   PMID:22056881   PMID:22172490   PMID:22574754   PMID:22764048  
PMID:22778717   PMID:23321698   PMID:23430746   PMID:23684747   PMID:24356001   PMID:24507550   PMID:24927531   PMID:25627423   PMID:25661788   PMID:26013143   PMID:26235810   PMID:26322371  
PMID:26531318   PMID:28158288   PMID:28254488   PMID:28371849   PMID:29040320   PMID:29603687   PMID:29677549   PMID:30206980   PMID:31976033   PMID:32398474   PMID:33545131   PMID:33754048  
PMID:33772408   PMID:34014836   PMID:34334085   PMID:35704246   PMID:35980290   PMID:36074222   PMID:36748222   PMID:37884859   PMID:38381247   PMID:38505381  


Genomics

Comparative Map Data
Mir375
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,939,817 - 74,939,880 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,939,817 - 74,939,880 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38174,900,658 - 74,900,721 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,900,658 - 74,900,721 (-)Ensemblmm10GRCm38
MGSCv37174,947,232 - 74,947,295 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera175,455,688 - 75,455,751 (-)NCBICelera
Cytogenetic Map1C4NCBI
cM Map138.54NCBI
MIR375
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,001,645 - 219,001,708 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,001,645 - 219,001,708 (-)Ensemblhg38GRCh38
GRCh372219,866,367 - 219,866,430 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,574,610 - 219,574,673 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2213,636,080 - 213,636,143 (-)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2211,720,395 - 211,720,458 (-)NCBIHuRef
CHM1_12219,873,820 - 219,873,883 (-)NCBICHM1_1
T2T-CHM13v2.02219,490,020 - 219,490,083 (-)NCBIT2T-CHM13v2.0
Mir375
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8983,906,582 - 83,906,656 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2976,457,911 - 76,457,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,457,911 - 76,457,985 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx984,902,918 - 84,902,992 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0990,031,868 - 90,031,942 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,418,026 - 88,418,100 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,161,716 - 82,161,790 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,161,716 - 82,161,790 (-)Ensemblrn6Rnor6.0
Rnor_5.0981,930,296 - 81,930,370 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera974,029,377 - 74,029,451 (-)NCBICelera
Cytogenetic Map9q33NCBI
MIR375
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13725,568,052 - 25,568,121 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3725,568,052 - 25,568,127 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3726,388,246 - 26,388,315 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03725,583,487 - 25,583,556 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3725,583,487 - 25,583,562 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13725,488,066 - 25,488,135 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,423,157 - 25,423,226 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,443,921 - 25,443,990 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0

miRNA Target Status (No longer updated)

Predicted Targets
Summary Value
Count of predictions:4818
Count of gene targets:2497
Count of transcripts:3760
Interacting mature miRNAs:mmu-miR-375-3p, mmu-miR-375-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1301714Vertcling_mvertical clinging (mouse)Not determined14293803176938167Mouse
4142394Mssq1_mmandible size and shape QTL 1 (mouse)Not determined73615692107615830Mouse
18182931Metl1_mmetabolite locus 1, pyridoxate (mouse)14127539975275399Mouse
4141305Tgq9_mtriglyceride QTL 9 (mouse)Not determined5142160585421605Mouse
4141625Emo4_memotionality 4 (mouse)Not determined6807134586235027Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1301211Bbaa11_mB.burgdorferi-associated arthritis 11 (mouse)Not determined14888900682889210Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
14697705Stsl3b_mSalmonella typhimurium susceptibility locus 3b (mouse)17413915981777715Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
1302146Cocrb1_mcocaine related behavior 1 (mouse)Not determined170133533104139557Mouse
1357505Vtbt1_mvertebral trabecular bone trait 1 (mouse)Not determined15626621490266360Mouse
4141032Wbcc1_mwhite blood cell count 1 (mouse)Not determined4225966776259667Mouse
14746998Mancz1_mmandible centroid size 1 (mouse)15794135191941351Mouse
1301444Alcw5_malcohol withdrawal 5 (mouse)Not determined15854919192549443Mouse
1300746Skl1_mskeletal size (tail length) 1 (mouse)Not determined15799197791992080Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
14747009Manh49_mmandible shape 49 (mouse)15794135191941351Mouse
1301616Yaa2_mY-linked autoimmune acceleration 2 (mouse)Not determined14685469080854839Mouse
1300976Bmd19_mbone mineral density 19 (mouse)Not determined173266214108838414Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
10043965Obq24_mobesity QTL 24 (mouse)Not determined15089021684890216Mouse
1301430Cdcs2_mcytokine deficiency colitis susceptibility 2 (mouse)Not determined14889234582892485Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162946755120529678Mouse
1558717Ses1a_msalmonella enteritidis susceptibility 1a (mouse)Not determined15672692290727077Mouse
1301304Hrq3_mheart rate quantitative locus 3 (mouse)Not determined173615692107615830Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1558905Gct7_mgranulosa cell tumorigenesis 7 (mouse)Not determined14734989481350013Mouse
4141393Mol2_mmodifier of LPS-response 2 (mouse)Not determined7162467978183144Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
1301667Lxw5_mlupus BXSB x NZW 5 (mouse)Not determined15854919192549443Mouse
1558822Vas1_mautoimmune vasitis resistance 1 (mouse)Not determined14888900682889210Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167339159129727737Mouse
1302119Cia15_mcollagen induced arthritis 15 (mouse)Not determined16588900688496101Mouse
1301670Ssta1_msusceptibility to Salmonella typhimurium antigens 1 (mouse)Not determined14594675579946882Mouse
1357741Nidd5k_mNidd5 on KK-A<y> (mouse)Not determined15597494889975057Mouse
1301162Skull1_mskull morphology 1 (mouse)Not determined15799197791992080Mouse
1301225Sle7_msystematic lupus erythematosus susceptibility 7 (mouse)Not determined14685469080854839Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
1357679Egrm1_mearly growth rate, maternal effect 1 (mouse)Not determined15799197791992080Mouse
4142467Wbcq1_mwhite blood cell quantitative locus 1 (mouse)Not determined15626621490266360Mouse
1301166Thypr2_mthymocyte proliferative response 2 (mouse)Not determined14127312475273271Mouse
1301933Insq6_minsulin QTL 6 (mouse)Not determined15672692290727077Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000083682
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,939,817 - 74,939,880 (-)Ensembl
GRCm38.p6 Ensembl174,900,658 - 74,900,721 (-)Ensembl
RefSeq Acc Id: NR_029876
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39174,939,817 - 74,939,880 (-)NCBI
GRCm38174,900,658 - 74,900,721 (-)ENTREZGENE
MGSCv37174,947,232 - 74,947,295 (-)RGD
Celera175,455,688 - 75,455,751 (-)RGD
cM Map1 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3619376 AgrOrtholog
Ensembl Genes ENSMUSG00000065616 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083682 ENTREZGENE
MGD MGI:3619376 ENTREZGENE
miRBase MI0000792 ENTREZGENE
NCBI Gene 723900 ENTREZGENE
PhenoGen Mir375 PhenoGen
RNAcentral URS00000ED600 RNACentral
  URS000075BCF9 RNACentral
  URS000075C0AF RNACentral