Adamts9 (ADAM metallopeptidase with thrombospondin type 1 motif, 9) - Rat Genome Database

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Gene: Adamts9 (ADAM metallopeptidase with thrombospondin type 1 motif, 9) Rattus norvegicus
Analyze
Symbol: Adamts9
Name: ADAM metallopeptidase with thrombospondin type 1 motif, 9
RGD ID: 1306889
Description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in several processes, including circulatory system development; negative regulation of endothelial cell migration; and negative regulation of sprouting angiogenesis. Predicted to act upstream of or within camera-type eye development; positive regulation of melanocyte differentiation; and response to bacterium. Predicted to be located in cell surface and extracellular space. Predicted to be active in extracellular matrix. Orthologous to human ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A disintegrin and metalloproteinase with thrombospondin motifs 9; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9; LOC312566
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84126,847,726 - 127,019,924 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4126,847,729 - 127,019,876 (-)EnsemblGRCr8
mRatBN7.24125,290,633 - 125,462,988 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4125,291,490 - 125,462,929 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4130,758,464 - 130,930,020 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04126,532,883 - 126,704,446 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04125,157,449 - 125,329,013 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04124,660,254 - 124,860,997 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4124,660,262 - 124,858,250 (-)Ensemblrn6Rnor6.0
Rnor_5.04188,409,387 - 188,604,223 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44126,996,604 - 127,198,909 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4114,207,098 - 114,377,105 (-)NCBICelera
RGSC_v3.14127,242,243 - 127,529,307 (-)NCBI
Cytogenetic Map4q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
3,4-dichloroaniline  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
choline  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclophosphamide  (EXP)
cytarabine  (ISO)
dexamethasone  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP,ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glycidol  (EXP)
hydrogen cyanide  (ISO)
hydrogen peroxide  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
methamphetamine  (EXP,ISO)
methimazole  (EXP)
mifepristone  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (ISO)
nevirapine  (EXP)
nickel atom  (ISO)
octadecanoic acid  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (EXP)
paracetamol  (EXP,ISO)
Phenelzine  (ISO)
phenytoin  (EXP)
pirinixic acid  (ISO)
potassium cyanide  (ISO)
progesterone  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
SCH 23390  (EXP)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)
zearalenone  (EXP,ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12514189   PMID:18454205   PMID:19348733   PMID:20093484   PMID:20096780   PMID:23012479   PMID:24220035  


Genomics

Comparative Map Data
Adamts9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84126,847,726 - 127,019,924 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4126,847,729 - 127,019,876 (-)EnsemblGRCr8
mRatBN7.24125,290,633 - 125,462,988 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4125,291,490 - 125,462,929 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4130,758,464 - 130,930,020 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04126,532,883 - 126,704,446 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04125,157,449 - 125,329,013 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04124,660,254 - 124,860,997 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4124,660,262 - 124,858,250 (-)Ensemblrn6Rnor6.0
Rnor_5.04188,409,387 - 188,604,223 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44126,996,604 - 127,198,909 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4114,207,098 - 114,377,105 (-)NCBICelera
RGSC_v3.14127,242,243 - 127,529,307 (-)NCBI
Cytogenetic Map4q34NCBI
ADAMTS9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38364,515,654 - 64,688,000 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl364,515,654 - 64,688,000 (-)Ensemblhg38GRCh38
GRCh37364,501,330 - 64,673,676 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36364,476,370 - 64,648,405 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34364,510,864 - 64,648,405NCBI
Celera364,518,077 - 64,690,097 (-)NCBICelera
Cytogenetic Map3p14.1NCBI
HuRef364,598,534 - 64,770,557 (-)NCBIHuRef
CHM1_1364,452,995 - 64,625,019 (-)NCBICHM1_1
T2T-CHM13v2.0364,559,268 - 64,731,664 (-)NCBIT2T-CHM13v2.0
Adamts9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39692,749,680 - 92,921,431 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl692,749,680 - 92,920,473 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38692,772,699 - 92,944,450 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl692,772,699 - 92,943,492 (-)Ensemblmm10GRCm38
MGSCv37692,722,693 - 92,851,435 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera694,664,224 - 94,793,353 (-)NCBICelera
Cytogenetic Map6D1NCBI
cM Map641.41NCBI
Adamts9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555171,302,922 - 1,440,245 (+)Ensembl
ChiLan1.0NW_0049555171,302,560 - 1,443,708 (+)NCBIChiLan1.0ChiLan1.0
ADAMTS9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2264,435,288 - 64,610,924 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1364,440,076 - 64,615,781 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0364,415,621 - 64,590,984 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1365,792,223 - 65,967,631 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl365,792,223 - 65,967,631 (-)EnsemblpanPan2panpan1.1
ADAMTS9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12026,589,529 - 26,749,422 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2026,588,654 - 26,748,604 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2026,514,671 - 26,674,068 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02026,630,243 - 26,790,304 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2026,629,348 - 26,789,486 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12026,324,394 - 26,484,009 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02026,676,416 - 26,835,956 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02026,736,222 - 26,895,640 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Adamts9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118163,398,425 - 163,556,712 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366371,788,276 - 1,942,833 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366371,787,987 - 1,946,250 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAMTS9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1346,034,833 - 46,207,006 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11346,033,753 - 46,209,238 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21350,519,007 - 50,690,497 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADAMTS9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12225,545,518 - 25,720,512 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2225,545,420 - 25,719,362 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041141,094,985 - 141,269,306 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adamts9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248881,333,714 - 1,474,897 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248881,333,534 - 1,474,776 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Adamts9
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1654,012,232 - 54,183,924 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Adamts9
1033 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:602
Count of miRNA genes:276
Interacting mature miRNAs:361
Transcripts:ENSRNOT00000057045
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)496731383141731383Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)492406430137406430Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4117737142152833657Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)488883695133883695Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4103834277148834277Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)488883695133883695Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)486058928131411333Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)484349032129349032Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)482336765127336765Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4113634167149763391Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)486583980131583980Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4121020385148834277Rat

Markers in Region
BE199318  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24125,290,924 - 125,291,033 (+)MAPPERmRatBN7.2
Rnor_6.04124,660,544 - 124,660,650NCBIRnor6.0
Rnor_5.04188,603,827 - 188,603,933UniSTSRnor5.0
RGSC_v3.44126,996,886 - 126,996,992UniSTSRGSC3.4
Celera4114,207,380 - 114,207,486UniSTS
Cytogenetic Map4q34UniSTS
RH137206  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24125,334,321 - 125,334,515 (+)MAPPERmRatBN7.2
Rnor_6.04124,703,969 - 124,704,162NCBIRnor6.0
Rnor_5.04188,560,617 - 188,560,810UniSTSRnor5.0
RGSC_v3.44127,070,381 - 127,070,574UniSTSRGSC3.4
Celera4114,249,679 - 114,249,872UniSTS
RH 3.4 Map4736.04UniSTS
Cytogenetic Map4q34UniSTS
AW743315  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24125,314,007 - 125,314,448 (+)MAPPERmRatBN7.2
Rnor_6.04124,683,529 - 124,683,969NCBIRnor6.0
Rnor_5.04188,580,810 - 188,581,250UniSTSRnor5.0
RGSC_v3.44127,050,078 - 127,050,518UniSTSRGSC3.4
Celera4114,229,376 - 114,229,816UniSTS
Cytogenetic Map4q34UniSTS
BF387413  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24125,290,721 - 125,290,883 (+)MAPPERmRatBN7.2
Rnor_6.04124,660,343 - 124,660,503NCBIRnor6.0
Rnor_5.04188,603,974 - 188,604,134UniSTSRnor5.0
RGSC_v3.44126,996,685 - 126,996,845UniSTSRGSC3.4
Celera4114,207,179 - 114,207,339UniSTS
RH 3.4 Map4736.83UniSTS
Cytogenetic Map4q34UniSTS
BE106470  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24125,358,315 - 125,358,367 (+)MAPPERmRatBN7.2
mRatBN7.24125,357,065 - 125,358,486 (+)MAPPERmRatBN7.2
mRatBN7.24125,358,315 - 125,358,486 (+)MAPPERmRatBN7.2
Rnor_6.04124,753,187 - 124,754,658NCBIRnor6.0
Rnor_6.04124,754,488 - 124,754,658NCBIRnor6.0
Rnor_5.04188,512,562 - 188,514,033UniSTSRnor5.0
Rnor_5.04188,512,562 - 188,512,732UniSTSRnor5.0
RGSC_v3.44127,094,378 - 127,094,548UniSTSRGSC3.4
Celera4114,273,667 - 114,273,837UniSTS
RH 3.4 Map4736.63UniSTS
Cytogenetic Map4q34UniSTS
BF409636  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24125,379,506 - 125,379,712 (+)MAPPERmRatBN7.2
Rnor_6.04124,775,699 - 124,775,904NCBIRnor6.0
Rnor_5.04188,491,253 - 188,491,458UniSTSRnor5.0
RGSC_v3.44127,115,566 - 127,115,771UniSTSRGSC3.4
Celera4114,294,847 - 114,295,052UniSTS
RH 3.4 Map4736.43UniSTS
Cytogenetic Map4q34UniSTS
RH136577  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0X16,473,541 - 16,473,725NCBIRnor5.0
Rnor_5.04188,532,081 - 188,532,265NCBIRnor5.0
Rnor_5.04188,475,121 - 188,475,305NCBIRnor5.0
RGSC_v3.4X26,878,172 - 26,878,355UniSTSRGSC3.4
RGSC_v3.44127,132,356 - 127,132,539UniSTSRGSC3.4
CeleraX14,920,644 - 14,920,827UniSTS
Celera4114,311,849 - 114,312,032UniSTS
Cytogenetic MapXq13UniSTS
Cytogenetic Map4q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 67 146 91 90 59 31 59 6 292 131 11 125 79 92 31 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000057045   ⟹   ENSRNOP00000053878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4126,852,734 - 127,019,876 (-)Ensembl
mRatBN7.2 Ensembl4125,291,490 - 125,462,929 (-)Ensembl
Rnor_6.0 Ensembl4124,660,262 - 124,858,250 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094375   ⟹   ENSRNOP00000097181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4126,847,729 - 127,019,876 (-)Ensembl
mRatBN7.2 Ensembl4125,333,719 - 125,462,592 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099874   ⟹   ENSRNOP00000089476
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4125,364,846 - 125,461,877 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114542   ⟹   ENSRNOP00000079368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4126,852,734 - 127,019,876 (-)Ensembl
mRatBN7.2 Ensembl4125,291,490 - 125,462,592 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114631   ⟹   ENSRNOP00000093214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4126,852,734 - 127,019,876 (-)Ensembl
mRatBN7.2 Ensembl4125,291,490 - 125,461,877 (-)Ensembl
RefSeq Acc Id: NM_001107877   ⟹   NP_001101347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84126,847,729 - 127,019,876 (-)NCBI
mRatBN7.24125,290,641 - 125,462,929 (-)NCBI
Rnor_6.04124,660,262 - 124,858,250 (-)NCBI
Rnor_5.04188,409,387 - 188,604,223 (+)NCBI
RGSC_v3.44126,996,604 - 127,198,909 (-)RGD
Celera4114,207,098 - 114,377,105 (-)RGD
Sequence:
RefSeq Acc Id: XM_063286077   ⟹   XP_063142147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84126,847,726 - 127,019,924 (-)NCBI
RefSeq Acc Id: XM_063286078   ⟹   XP_063142148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84126,852,843 - 127,019,924 (-)NCBI
RefSeq Acc Id: XM_063286080   ⟹   XP_063142150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84126,863,798 - 127,019,924 (-)NCBI
RefSeq Acc Id: XM_063286081   ⟹   XP_063142151
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84126,847,726 - 127,019,924 (-)NCBI
RefSeq Acc Id: XR_010065646
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84126,852,784 - 127,019,924 (-)NCBI
RefSeq Acc Id: NP_001101347   ⟸   NM_001107877
- Peptide Label: precursor
- Sequence:
Ensembl Acc Id: ENSRNOP00000053878   ⟸   ENSRNOT00000057045
Ensembl Acc Id: ENSRNOP00000089476   ⟸   ENSRNOT00000099874
Ensembl Acc Id: ENSRNOP00000093214   ⟸   ENSRNOT00000114631
Ensembl Acc Id: ENSRNOP00000097181   ⟸   ENSRNOT00000094375
Ensembl Acc Id: ENSRNOP00000079368   ⟸   ENSRNOT00000114542
RefSeq Acc Id: XP_063142151   ⟸   XM_063286081
- Peptide Label: isoform X4
- UniProtKB: A6IBC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142147   ⟸   XM_063286077
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063142148   ⟸   XM_063286078
- Peptide Label: isoform X2
- UniProtKB: A6IBC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142150   ⟸   XM_063286080
- Peptide Label: isoform X3
- UniProtKB: A6IBC6 (UniProtKB/TrEMBL)
Protein Domains
GON   Peptidase M12B

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZMB0-F1-model_v2 AlphaFold D3ZMB0 1-1880 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693261
Promoter ID:EPDNEW_R3786
Type:single initiation site
Name:Adamts9_1
Description:ADAM metallopeptidase with thrombospondin type 1 motif, 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04124,858,282 - 124,858,342EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306889 AgrOrtholog
BioCyc Gene G2FUF-43691 BioCyc
Ensembl Genes ENSRNOG00000023257 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057045 ENTREZGENE
  ENSRNOT00000057045.4 UniProtKB/TrEMBL
  ENSRNOT00000094375.2 UniProtKB/TrEMBL
  ENSRNOT00000114542 ENTREZGENE
  ENSRNOT00000114542.2 UniProtKB/TrEMBL
  ENSRNOT00000114631.2 UniProtKB/TrEMBL
Gene3D-CATH 2.20.100.10 UniProtKB/TrEMBL
  2.60.120.830 UniProtKB/TrEMBL
  3.40.1620.60 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro ADAM_spacer1 UniProtKB/TrEMBL
  ADAMTS/ADAMTS-like UniProtKB/TrEMBL
  ADAMTS_ADAMTS-like UniProtKB/TrEMBL
  ADAMTS_CR_2 UniProtKB/TrEMBL
  ADAMTS_CR_3 UniProtKB/TrEMBL
  MetalloPept_cat_dom UniProtKB/TrEMBL
  Pept_M12B_GON-ADAMTSs UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  Thrombospondin_1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
KEGG Report rno:312566 UniProtKB/TrEMBL
NCBI Gene 312566 ENTREZGENE
PANTHER A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 9 UniProtKB/TrEMBL
  ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE UniProtKB/TrEMBL
  PAPILIN UniProtKB/TrEMBL
Pfam ADAM_CR_2 UniProtKB/TrEMBL
  ADAM_CR_3 UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/TrEMBL
  GON UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
  TSP1_ADAMTS UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PhenoGen Adamts9 PhenoGen
PRINTS ADAMTSFAMILY UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  GON UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000023257 RatGTEx
SMART TSP1 UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
UniProt A0A8I6AIJ2_RAT UniProtKB/TrEMBL
  A0A8I6AUM2_RAT UniProtKB/TrEMBL
  A0A8I6G579_RAT UniProtKB/TrEMBL
  A6IBC6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZMB0_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-13 Adamts9  ADAM metallopeptidase with thrombospondin type 1 motif, 9  Adamts9  a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Adamts9  a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9   Adamts9_predicted  a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Adamts9_predicted  a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 (predicted)      Symbol and Name status set to approved 70820 APPROVED