Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mark3 | Rat | visual impairment and progressive phthisis bulbi | | ISO | MARK3 (Homo sapiens) | 7240710 | | OMIM | | |
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mark3 | Rat | visual impairment and progressive phthisis bulbi | | ISO | MARK3 (Homo sapiens) | 7240710 | | OMIM | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
3. | C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding. | Peng CY, etal., Cell Growth Differ. 1998 Mar;9(3):197-208. |
4. | GOA pipeline | RGD automated data pipeline |
5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
7. | Information Derived from GenBank Report | RGD, Sept. 2003 |
PMID:16980613 | PMID:18570454 | PMID:21145462 | PMID:23666762 | PMID:25931508 | PMID:28087714 |
Mark3 (Rattus norvegicus - Norway rat) |
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MARK3 (Homo sapiens - human) |
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Mark3 (Mus musculus - house mouse) |
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Mark3 (Chinchilla lanigera - long-tailed chinchilla) |
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MARK3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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MARK3 (Canis lupus familiaris - dog) |
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Mark3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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MARK3 (Sus scrofa - pig) |
No map positions available. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
MARK3 (Chlorocebus sabaeus - green monkey) |
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Mark3 (Heterocephalus glaber - naked mole-rat) |
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Variants in Mark3
264 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
BE120426 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 43 | 57 | 41 | 19 | 41 | 8 | 11 | 74 | 35 | 41 | 11 | 8 |
Low | |||||||||||||
Below cutoff |
RefSeq Transcripts | NM_130749 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006240563 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006240564 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594010 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594011 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594012 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594013 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594014 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594015 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594017 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594018 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039111715 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039111717 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039111718 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039111720 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039111721 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039111723 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039111724 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039111725 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063261495 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063261496 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063261497 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063261498 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063261499 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063261500 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063261501 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063261502 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063261503 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AF465412 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
CH474034 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ214295 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ235189 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000006 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000014395 ⟹ ENSRNOP00000014395 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000080304 ⟹ ENSRNOP00000068972 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000088784 ⟹ ENSRNOP00000073297 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000092806 ⟹ ENSRNOP00000075961 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000094828 ⟹ ENSRNOP00000091306 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000105097 ⟹ ENSRNOP00000082974 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_130749 ⟹ NP_570105 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006240563 ⟹ XP_006240625 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017594010 ⟹ XP_017449499 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017594011 ⟹ XP_017449500 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039111715 ⟹ XP_038967643 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039111717 ⟹ XP_038967645 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039111718 ⟹ XP_038967646 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039111720 ⟹ XP_038967648 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039111721 ⟹ XP_038967649 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039111723 ⟹ XP_038967651 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039111724 ⟹ XP_038967652 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039111725 ⟹ XP_038967653 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063261495 ⟹ XP_063117565 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063261496 ⟹ XP_063117566 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063261497 ⟹ XP_063117567 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063261498 ⟹ XP_063117568 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063261499 ⟹ XP_063117569 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063261500 ⟹ XP_063117570 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063261501 ⟹ XP_063117571 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063261502 ⟹ XP_063117572 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063261503 ⟹ XP_063117573 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_570105 | (Get FASTA) | NCBI Sequence Viewer |
XP_006240625 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017449499 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017449500 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038967643 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038967645 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038967646 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038967648 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038967649 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038967651 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038967652 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038967653 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063117565 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063117566 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063117567 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063117568 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063117569 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063117570 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063117571 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063117572 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063117573 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAL69981 | (Get FASTA) | NCBI Sequence Viewer |
EDL97458 | (Get FASTA) | NCBI Sequence Viewer | |
EDL97459 | (Get FASTA) | NCBI Sequence Viewer | |
EDL97460 | (Get FASTA) | NCBI Sequence Viewer | |
EDL97461 | (Get FASTA) | NCBI Sequence Viewer | |
EDL97462 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000014395 | ||
ENSRNOP00000014395.4 | |||
ENSRNOP00000068972 | |||
ENSRNOP00000068972.2 | |||
ENSRNOP00000073297 | |||
ENSRNOP00000073297.1 | |||
ENSRNOP00000075961.2 | |||
ENSRNOP00000082974.1 | |||
ENSRNOP00000091306.1 | |||
GenBank Protein | Q8VHF0 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_570105 ⟸ NM_130749 |
- UniProtKB: | Q8VHF0 (UniProtKB/Swiss-Prot), A0A0G2K554 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006240625 ⟸ XM_006240563 |
- Peptide Label: | isoform X6 |
- UniProtKB: | A0A0G2K554 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017449500 ⟸ XM_017594011 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A6KBR9 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017449499 ⟸ XM_017594010 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A6KBR9 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000068972 ⟸ ENSRNOT00000080304 |
RefSeq Acc Id: | ENSRNOP00000075961 ⟸ ENSRNOT00000092806 |
RefSeq Acc Id: | ENSRNOP00000014395 ⟸ ENSRNOT00000014395 |
RefSeq Acc Id: | ENSRNOP00000073297 ⟸ ENSRNOT00000088784 |
RefSeq Acc Id: | XP_038967651 ⟸ XM_039111723 |
- Peptide Label: | isoform X18 |
RefSeq Acc Id: | XP_038967649 ⟸ XM_039111721 |
- Peptide Label: | isoform X12 |
- UniProtKB: | A0A0G2K554 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038967646 ⟸ XM_039111718 |
- Peptide Label: | isoform X7 |
- UniProtKB: | F1M836 (UniProtKB/TrEMBL), A0A0G2K554 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038967643 ⟸ XM_039111715 |
- Peptide Label: | isoform X4 |
- UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038967645 ⟸ XM_039111717 |
- Peptide Label: | isoform X5 |
- UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038967648 ⟸ XM_039111720 |
- Peptide Label: | isoform X9 |
RefSeq Acc Id: | XP_038967652 ⟸ XM_039111724 |
- Peptide Label: | isoform X19 |
RefSeq Acc Id: | XP_038967653 ⟸ XM_039111725 |
- Peptide Label: | isoform X20 |
RefSeq Acc Id: | ENSRNOP00000091306 ⟸ ENSRNOT00000094828 |
RefSeq Acc Id: | ENSRNOP00000082974 ⟸ ENSRNOT00000105097 |
RefSeq Acc Id: | XP_063117565 ⟸ XM_063261495 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063117566 ⟸ XM_063261496 |
- Peptide Label: | isoform X8 |
- UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063117567 ⟸ XM_063261497 |
- Peptide Label: | isoform X10 |
- UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063117568 ⟸ XM_063261498 |
- Peptide Label: | isoform X11 |
- UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063117570 ⟸ XM_063261500 |
- Peptide Label: | isoform X14 |
- UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL), A0A8I6GIW6 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063117572 ⟸ XM_063261502 |
- Peptide Label: | isoform X16 |
- UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063117573 ⟸ XM_063261503 |
- Peptide Label: | isoform X17 |
- UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063117571 ⟸ XM_063261501 |
- Peptide Label: | isoform X15 |
- UniProtKB: | A0A0G2K554 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063117569 ⟸ XM_063261499 |
- Peptide Label: | isoform X13 |
- UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q8VHF0-F1-model_v2 | AlphaFold | Q8VHF0 | 1-797 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:619883 | AgrOrtholog |
BioCyc Gene | G2FUF-35837 | BioCyc |
Ensembl Genes | ENSRNOG00000010330 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000014395.5 | UniProtKB/TrEMBL |
ENSRNOT00000080304.2 | UniProtKB/TrEMBL | |
ENSRNOT00000088784 | ENTREZGENE | |
ENSRNOT00000088784.3 | UniProtKB/TrEMBL | |
ENSRNOT00000092806.2 | UniProtKB/TrEMBL | |
ENSRNOT00000094828.1 | UniProtKB/TrEMBL | |
ENSRNOT00000105097.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | DNA helicase RuvA subunit, C-terminal domain | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Kinase associated domain 1, KA1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Transferase(Phosphotransferase) domain 1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
InterPro | KA1/Ssp2_C | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
KA1_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Kinase-like_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
MARK1-4_cat | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Prot_kinase_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Protein_kinase_ATP_BS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Ser/Thr_kinase_AS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UBA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:170577 | UniProtKB/Swiss-Prot |
NCBI Gene | 170577 | ENTREZGENE |
PANTHER | MAP/MICROTUBULE AFFINITY-REGULATING KINASE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PTHR24346:SF1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SERINE_THREONINE-PROTEIN KINASE MARK2 | UniProtKB/TrEMBL | |
Pfam | KA1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Pkinase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UBA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Mark3 | PhenoGen |
PROSITE | KA1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROTEIN_KINASE_ATP | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PROTEIN_KINASE_DOM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PROTEIN_KINASE_ST | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UBA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000010330 | RatGTEx |
SMART | S_TKc | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UBA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Superfamily-SCOP | SSF103243 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SSF56112 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UniProt | A0A0G2JU56 | ENTREZGENE, UniProtKB/TrEMBL |
A0A0G2K554 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A1B0GWN5_RAT | UniProtKB/TrEMBL | |
A0A8I5ZV33_RAT | UniProtKB/TrEMBL | |
A0A8I6GIW6 | ENTREZGENE, UniProtKB/TrEMBL | |
A6KBR9 | ENTREZGENE, UniProtKB/TrEMBL | |
A6KBS0_RAT | UniProtKB/TrEMBL | |
A6KBS3_RAT | UniProtKB/TrEMBL | |
F1M836 | ENTREZGENE, UniProtKB/TrEMBL | |
MARK3_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2016-02-17 | Mark3 | microtubule affinity regulating kinase 3 | Mark3 | MAP/microtubule affinity-regulating kinase 3 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2004-09-10 | Mark3 | MAP/microtubule affinity-regulating kinase 3 | Symbol and Name status set to approved | 1299863 | APPROVED | ||
2002-08-07 | Mark3 | MAP/microtubule affinity-regulating kinase 3 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |