Tmem52 (transmembrane protein 52)

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Gene: Tmem52 (transmembrane protein 52) Rattus norvegicus

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Symbol:

Tmem52

Name:

transmembrane protein 52

RGD ID:

2318502

Description:

Predicted to be located in membrane. Orthologous to human TMEM52 (transmembrane protein 52); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; fenvalerate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC100362283; rCG31224-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM52 (transmembrane protein 52)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Tmem52 (transmembrane protein 52)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem52 (transmembrane protein 52)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM52 (transmembrane protein 52)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM52 (transmembrane protein 52)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem52 (transmembrane protein 52)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM52 (transmembrane protein 52)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOC103225776 (transmembrane protein 52)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem52 (transmembrane protein 52)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TMEM52 (transmembrane protein 52)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tmem52 (transmembrane protein 52)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	171,330,948 - 171,332,704 (+)	NCBI		GRCr8
mRatBN7.2	5	166,048,669 - 166,050,423 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	166,046,565 - 166,050,433 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	168,753,717 - 168,755,455 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	170,575,131 - 170,576,869 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	170,537,671 - 170,539,409 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	172,887,587 - 172,889,349 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	172,887,217 - 172,889,383 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	176,345,479 - 176,347,227 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	172,293,187 - 172,294,894 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	164,250,432 - 164,252,194 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 1p36 deletion syndrome (ISO)

congenital myasthenic syndrome 8 (ISO)

dilated cardiomyopathy 1LL (ISO)

Ehlers-Danlos syndrome spondylodysplastic type 2 (ISO)

Goldberg-Shprintzen syndrome (ISO)

idiopathic generalized epilepsy (ISO)

immunodeficiency 16 (ISO)

immunodeficiency 38 (ISO)

Joubert syndrome 25 (ISO)

Neurodevelopmental Disorders (ISO)

Peroxisome Biogenesis Disorder, Complementation Group 7 (ISO)

Shprintzen-Goldberg Craniosynostosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4-D (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

actinomycin D (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

butanal (ISO)

cadmium dichloride (ISO)

camptothecin (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

diquat (ISO)

dorsomorphin (ISO)

fenvalerate (EXP)

fructose (ISO)

fulvestrant (ISO)

glucose (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-4-phenylpyridinium (ISO)

niclosamide (ISO)

Nutlin-3 (ISO)

paracetamol (ISO)

pentanal (ISO)

perfluorooctanoic acid (EXP)

phenylmercury acetate (ISO)

propanal (ISO)

resveratrol (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

testosterone (ISO)

titanium dioxide (ISO)

tris(2-butoxyethyl) phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

membrane (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Tmem52
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	171,330,948 - 171,332,704 (+)	NCBI		GRCr8
mRatBN7.2	5	166,048,669 - 166,050,423 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	166,046,565 - 166,050,433 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	168,753,717 - 168,755,455 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	170,575,131 - 170,576,869 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	170,537,671 - 170,539,409 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	172,887,587 - 172,889,349 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	172,887,217 - 172,889,383 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	176,345,479 - 176,347,227 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	172,293,187 - 172,294,894 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	164,250,432 - 164,252,194 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

TMEM52
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	1,917,591 - 1,919,279 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	1,917,590 - 1,919,279 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	1,849,030 - 1,850,718 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	1,838,890 - 1,840,567 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	744,314 - 746,025 (+)	NCBI		Celera
Cytogenetic Map	1	p36.33	NCBI
HuRef	1	1,126,011 - 1,127,713 (-)	NCBI		HuRef
CHM1_1	1	1,836,054 - 1,837,765 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	1,352,013 - 1,353,729 (-)	NCBI		T2T-CHM13v2.0

Tmem52
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	155,553,571 - 155,555,315 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	155,553,571 - 155,555,315 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	155,469,114 - 155,470,858 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	155,469,114 - 155,470,858 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	154,843,224 - 154,844,805 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	154,312,934 - 154,326,429 (+)	NCBI		MGSCv36	mm8
Celera	4	157,743,815 - 157,745,396 (+)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	86.17	NCBI

Tmem52
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	9,109,431 - 9,110,668 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955486	9,107,254 - 9,111,006 (+)	NCBI	ChiLan1.0	ChiLan1.0

TMEM52
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	226,355,631 - 226,357,941 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	225,011,502 - 225,013,812 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	623,603 - 626,169 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	1,780,877 - 1,782,570 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	1,780,877 - 1,782,570 (-)	Ensembl	panpan1.1		panPan2

TMEM52
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	56,900,297 - 56,906,565 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	56,901,674 - 56,906,500 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	56,975,580 - 56,981,858 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	57,102,037 - 57,108,315 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	5	57,092,601 - 57,098,879 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	56,985,109 - 56,991,387 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	57,374,951 - 57,381,229 (-)	NCBI		UU_Cfam_GSD_1.0

Tmem52
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	27,997,947 - 27,999,782 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936737	1,466,168 - 1,468,003 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM52
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	63,969,440 - 63,974,286 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	63,969,438 - 63,974,312 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	58,546,766 - 58,548,674 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103225776
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	129,629,065 - 129,630,819 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666674	19,676 - 21,418 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem52
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	7,918,625 - 7,920,138 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624818	7,916,889 - 7,920,138 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	88
Count of miRNA genes:	40
Interacting mature miRNAs:	42
Transcripts:	ENSRNOT00000022286, ENSRNOT00000072623
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631272	Lanf1	Left ventricular atrial natriuretic factor QTL 1	12		heart left ventricle natriuretic peptide A amount (VT:0010596)	heart left ventricle natriuretic peptide A level (CMO:0002165)	5	151113452	166875058	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1549904	Neuinf1	Neuroinflammation QTL 1	3	0	nervous system integrity trait (VT:0010566)	blood T lymphocyte count (CMO:0000110)	5	154828214	166875058	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	143069996	166846814	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat

Markers in Region

D5Rat51

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	166,048,082 - 166,048,206 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	172,887,011 - 172,887,134	NCBI	Rnor6.0
Rnor_5.0	5	176,344,889 - 176,345,012	UniSTS	Rnor5.0
RGSC_v3.4	5	172,292,556 - 172,292,679	UniSTS	RGSC3.4
RGSC_v3.4	5	172,292,555 - 172,292,679	RGD	RGSC3.4
RGSC_v3.1	5	172,303,051 - 172,303,174	RGD
Celera	5	164,249,856 - 164,249,979	UniSTS
RH 3.4 Map	5	1154.2	RGD
RH 3.4 Map	5	1154.2	UniSTS
RH 2.0 Map	5	1139.9	RGD
SHRSP x BN Map	5	105.0899	RGD

RH134285

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	166,050,147 - 166,050,367 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	172,889,076 - 172,889,295	NCBI	Rnor6.0
Rnor_5.0	5	176,346,954 - 176,347,173	UniSTS	Rnor5.0
RGSC_v3.4	5	172,294,621 - 172,294,840	UniSTS	RGSC3.4
Celera	5	164,251,921 - 164,252,140	UniSTS
RH 3.4 Map	5	1155.5	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
8	11	27	104	82	81	50	25	50	6	183	75	84	42	55	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001399170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_002726665	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006225637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111393	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC130035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022286 ⟹ ENSRNOP00000022286

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	166,046,565 - 166,050,433 (+)	Ensembl
Rnor_6.0 Ensembl	5	172,887,217 - 172,889,383 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110781 ⟹ ENSRNOP00000084425

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	166,048,580 - 166,050,433 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115596 ⟹ ENSRNOP00000083157

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	166,048,580 - 166,050,433 (+)	Ensembl

RefSeq Acc Id:

NM_001399170 ⟹ NP_001386099

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	171,330,966 - 171,332,704 (+)	NCBI
mRatBN7.2	5	166,048,683 - 166,050,421 (+)	NCBI

RefSeq Acc Id:

XM_006239606 ⟹ XP_006239668

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	171,331,149 - 171,332,701 (+)	NCBI
mRatBN7.2	5	166,048,669 - 166,050,423 (+)	NCBI
Rnor_6.0	5	172,887,799 - 172,889,349 (+)	NCBI
Rnor_5.0	5	176,345,479 - 176,347,227 (+)	NCBI

Sequence:

show sequence

GGTGACGCTGGGTACCGCGGATGGCAACTGTGATCCCTCGGATCAGTGCCCGCCCCAGGCCCGC
TGGAGCAACCTATGGCATGTGGGTCTGAAGAGCACTTGAGCCCTAGGCAGCCTTGGAAACCAGA
CCCGACCATCCTCTGCAGAAGGCACAAGGACCGTGCAGTTGTCTGGGGACAGCATGTCCTGGGA
GTGAACCCAAAGCCACCCCTGGCCAGCACTGGAGAGCCAAGCCAGGACTGGCCCCAGCTGGAAG
AGACCAGCGCAGGCGGCTCCTCAGGCCTGAAGTCAGCTGAGGAAGTGTTTGGCGCGGAAAGACA
TCTCTTGCTTTGTTTTCACCTGTCGGTTATCCTGTTTTGGGTGGTTAGGCAGGACAGACCCCCC
GGGTGCAGGTGCCCAGTGACAGAAGGCCAGTCCAGTGGTAGATCCTTGCTCTCCCTTGTCAGGC
TTACCCTGCTTGCCATATTCCTGATGCTTCTGTGTGGGGTCACAGCCAGTTGTGTACGACTCTG
CTGCCTCAGGAAACAGCCTCACACCCAGACACACACGCCAGCAGCATGGCAGCCCTGTGACGGG
ACAGTCATCCCTATGGACAGCGACAGCCCTGCACACAGCACTGTGACCTCCTACAGCTCCGTGC
AGTACCCACTGGGCATGCGGTTGCCCCTGTACTTTGGTGAGCCAGACCCTGACTCCATGGTACC
CCCCACCTACAGCCTATACCCTACAGAGCTGCCACCCTCCTATGATGAAGTTGTGAAGATGATA
AAAGCCAGGGAGGAGGCAGCAGCTCCCTCTGAGAGAACCAACCCTCTGCCAGAGGCCTCTGAGC
TAGAGACCACTGGAGGGCCCCAGGAGTCAGGCCCCACTCCCTAGCGGCCCTAGCTACACCCGTT
TGCAAAGAGTGGGTGTTCTTTCTCCTGGAGCCATTAAACCCCATCCTGGATTCCCGAGACCAAG
GAAACCCACCCGTGTCATCCTTCCCCCGGGAAGGCCAGCCATCCAGCACATTGCTGCAGACTCT
CGGCCTCATTGCTATGCAATGCCTGGCCAGCCAGCCTGCCCTCCCACCCATCGGGGCCCAGCAG
ACCCTCACCACGGAGGAGCCTGGATCTTGGGAACTCAAGCCCCACTGGCCTGTCAGCCCTCTGA
GGGGAAAATAAAGTTTATGTAAACGTGGTC

hide sequence

RefSeq Acc Id:

XM_039111393 ⟹ XP_038967321

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	171,330,948 - 171,332,701 (+)	NCBI
mRatBN7.2	5	166,048,680 - 166,050,423 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001386099	(Get FASTA)	NCBI Sequence Viewer
	XP_006239668	(Get FASTA)	NCBI Sequence Viewer
	XP_038967321	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL81302	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022286.6
	ENSRNOP00000083157.1
	ENSRNOP00000084425.1

RefSeq Acc Id:	XP_006239668 ⟸ XM_006239606
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZVZ9 (UniProtKB/TrEMBL), A0A8I6A194 (UniProtKB/TrEMBL)
- Sequence:	show sequence MACGSEEHLSPRQPWKPDPTILCRRHKDRAVVWGQHVLGVNPKPPLASTGEPSQDWPQLEETSA GGSSGLKSAEEVFGAERHLLLCFHLSVILFWVVRQDRPPGCRCPVTEGQSSGRSLLSLVRLTLL AIFLMLLCGVTASCVRLCCLRKQPHTQTHTPAAWQPCDGTVIPMDSDSPAHSTVTSYSSVQYPL GMRLPLYFGEPDPDSMVPPTYSLYPTELPPSYDEVVKMIKAREEAAAPSERTNPLPEASELETT GGPQESGPTP hide sequence

Ensembl Acc Id:

ENSRNOP00000022286 ⟸ ENSRNOT00000022286

RefSeq Acc Id:	XP_038967321 ⟸ XM_039111393
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000084425 ⟸ ENSRNOT00000110781

Ensembl Acc Id:

ENSRNOP00000083157 ⟸ ENSRNOT00000115596

RefSeq Acc Id:	NP_001386099 ⟸ NM_001399170
- Peptide Label:	precursor
- UniProtKB:	D3ZP55 (UniProtKB/TrEMBL), A6IUQ1 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZP55-F1-model_v2	AlphaFold	D3ZP55	1-193	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694337

Promoter ID:

EPDNEW_R4844

Type:

multiple initiation site

Name:

Tmem52_1

Description:

transmembrane protein 52

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	172,887,631 - 172,887,691	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2318502	AgrOrtholog
BioCyc Gene	G2FUF-38926	BioCyc
Ensembl Genes	ENSRNOG00000016618	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000022286.8	UniProtKB/TrEMBL
	ENSRNOT00000110781.1	UniProtKB/TrEMBL
	ENSRNOT00000115596.1	UniProtKB/TrEMBL
InterPro	TMEM52	UniProtKB/TrEMBL
NCBI Gene	100362283	ENTREZGENE
PANTHER	PTHR33955	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 52	UniProtKB/TrEMBL
Pfam	TMEM52	UniProtKB/TrEMBL
PhenoGen	Tmem52	PhenoGen
RatGTEx	ENSRNOG00000016618	RatGTEx
UniProt	A0A8I5ZVZ9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A194	ENTREZGENE, UniProtKB/TrEMBL
	A6IUQ1	ENTREZGENE, UniProtKB/TrEMBL
	D3ZP55	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-08-27	Tmem52	transmembrane protein 52	LOC100362283	rCG31224-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-05	LOC100362283	rCG31224-like			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar