Acsf3 (acyl-CoA synthetase family member 3) - Rat Genome Database

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Gene: Acsf3 (acyl-CoA synthetase family member 3) Heterocephalus glaber
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Symbol: Acsf3
Name: acyl-CoA synthetase family member 3
RGD ID: 18929384
Description: ENCODES a protein that exhibits very long-chain fatty acid-CoA ligase activity (ortholog); INVOLVED IN fatty acid biosynthetic process (inferred); fatty acid metabolic process (inferred); lipid metabolic process (inferred); ASSOCIATED WITH combined malonic and methylmalonic acidemia (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acyl-CoA synthetase family member 3, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746628,010 - 655,950 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624746627,089 - 655,922 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
mitochondrion  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Acsf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746628,010 - 655,950 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624746627,089 - 655,922 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
ACSF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381689,093,852 - 89,156,233 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1689,088,375 - 89,164,121 (+)Ensemblhg38GRCh38
GRCh371689,160,260 - 89,222,641 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,687,825 - 87,749,670 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1674,226,564 - 74,287,794 (+)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1674,859,689 - 74,921,455 (+)NCBIHuRef
CHM1_11690,571,314 - 90,633,459 (+)NCBICHM1_1
T2T-CHM13v2.01695,173,811 - 95,236,254 (+)NCBIT2T-CHM13v2.0
Acsf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,502,209 - 123,544,626 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,502,225 - 123,544,619 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388122,775,470 - 122,817,887 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,775,486 - 122,817,880 (+)Ensemblmm10GRCm38
MGSCv378125,299,405 - 125,341,781 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368125,666,626 - 125,703,971 (+)NCBIMGSCv36mm8
Celera8127,007,875 - 127,052,230 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map871.97NCBI
Acsf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,743,660 - 67,784,109 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1967,743,490 - 67,784,084 (+)EnsemblGRCr8
mRatBN7.21950,835,116 - 50,875,557 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,835,221 - 50,875,553 (+)EnsemblmRatBN7.2
Dahl_SR_JrHsd1961,541,823 - 61,582,002 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1959,664,649 - 59,705,049 (+)NCBILyon_Normotensive
Lyon_Hypertensive1961,538,117 - 61,578,516 (+)NCBILyon_Hypertensive
F344_StmMcwi1959,272,799 - 59,312,843 (+)NCBIF344_StmMcwi
Rnor_6.01955,594,801 - 55,635,312 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,594,831 - 55,635,122 (+)Ensemblrn6Rnor6.0
Rnor_5.01966,302,623 - 66,342,436 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41953,066,291 - 53,106,673 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1950,073,106 - 50,113,121 (+)NCBICelera
Cytogenetic Map19q12NCBI
Acsf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,837,448 - 2,876,316 (+)Ensembl
ChiLan1.0NW_0049555412,837,487 - 2,876,220 (+)NCBIChiLan1.0ChiLan1.0
ACSF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,874,350 - 98,940,718 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,790,399 - 104,854,970 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,842,709 - 69,907,075 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,465,691 - 89,524,210 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,467,997 - 89,523,825 (+)EnsemblpanPan2panpan1.1
ACSF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,288,339 - 64,338,596 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,289,295 - 64,414,637 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha564,304,235 - 64,354,696 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0564,519,689 - 64,569,550 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,515,871 - 64,569,789 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,539,014 - 64,589,483 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,377,020 - 64,427,451 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0564,783,458 - 64,833,225 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Acsf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,946,656 - 24,983,470 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641700,187 - 736,941 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936641700,218 - 736,875 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACSF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6663,123 - 709,186 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16663,201 - 708,800 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26826,070 - 843,606 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACSF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,464,357 - 74,526,173 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,464,651 - 74,525,660 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660471,014,211 - 1,082,877 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acsf3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11742,410,203 - 42,449,632 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000013982   ⟹   ENSHGLP00000013841
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624746628,010 - 655,950 (-)Ensembl
RefSeq Acc Id: XM_004842655   ⟹   XP_004842712
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746627,089 - 655,922 (-)NCBI
RefSeq Acc Id: XM_021256558   ⟹   XP_021112217
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746636,069 - 655,922 (-)NCBI
RefSeq Acc Id: XM_021256559   ⟹   XP_021112218
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746627,089 - 655,922 (-)NCBI
RefSeq Acc Id: XR_002394215
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746627,089 - 655,922 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004842712 (Get FASTA)   NCBI Sequence Viewer  
  XP_021112217 (Get FASTA)   NCBI Sequence Viewer  
  XP_021112218 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000013841
GenBank Protein JAN98894 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021112218   ⟸   XM_021256559
- Peptide Label: isoform X3
- UniProtKB: A0AAX6SU72 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842712   ⟸   XM_004842655
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JE90 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112217   ⟸   XM_021256558
- Peptide Label: isoform X2
- UniProtKB: A0AAX6SSY8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000013841   ⟸   ENSHGLT00000013982


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009893 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000013982 ENTREZGENE
Gene3D-CATH 3.30.300.30 UniProtKB/TrEMBL
  3.40.50.12780 UniProtKB/TrEMBL
InterPro AMP-bd_C UniProtKB/TrEMBL
  AMP-bd_C_sf UniProtKB/TrEMBL
  AMP-binding_CS UniProtKB/TrEMBL
  AMP-dep_Synth/Lig UniProtKB/TrEMBL
  ANL_N_sf UniProtKB/TrEMBL
KEGG Report hgl:101708737 UniProtKB/TrEMBL
NCBI Gene Acsf3 ENTREZGENE
PANTHER ACYL-COA SYNTHETASE UniProtKB/TrEMBL
  FATTY ACID COA SYNTHETASE FAMILY UniProtKB/TrEMBL
Pfam AMP-binding UniProtKB/TrEMBL
  AMP-binding_C UniProtKB/TrEMBL
PROSITE AMP_BINDING UniProtKB/TrEMBL
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/TrEMBL
UniProt A0A0P6JE90 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SSY8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SU72 ENTREZGENE, UniProtKB/TrEMBL