Acsf3 (acyl-CoA synthetase family member 3) - Rat Genome Database

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Gene: Acsf3 (acyl-CoA synthetase family member 3) Chinchilla lanigera
Analyze
Symbol: Acsf3
Name: acyl-CoA synthetase family member 3
RGD ID: 8826539
Description: ENCODES a protein that exhibits acid-thiol ligase activity (ortholog); malonyl-CoA synthetase activity (ortholog); very long-chain fatty acid-CoA ligase activity (ortholog); INVOLVED IN fatty acid biosynthetic process (ortholog); fatty acid metabolic process (ortholog); malonate catabolic process (ortholog); ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); autosomal recessive chronic granulomatous disease 4 (ortholog); combined malonic and methylmalonic acidemia (ortholog); FOUND IN mitochondrion (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acyl-CoA synthetase family member 3, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,837,448 - 2,876,316 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,837,487 - 2,876,220 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Acsf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,837,448 - 2,876,316 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,837,487 - 2,876,220 (+)NCBIChiLan1.0ChiLan1.0
ACSF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381689,093,852 - 89,156,233 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1689,088,375 - 89,164,121 (+)EnsemblGRCh38hg38GRCh38
GRCh371689,160,260 - 89,222,641 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,687,825 - 87,749,670 (+)NCBINCBI36Build 36hg18NCBI36
Celera1674,226,564 - 74,287,794 (+)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1674,859,689 - 74,921,455 (+)NCBIHuRef
CHM1_11690,571,314 - 90,633,459 (+)NCBICHM1_1
T2T-CHM13v2.01695,173,811 - 95,236,254 (+)NCBIT2T-CHM13v2.0
Acsf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,502,209 - 123,544,626 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,502,225 - 123,544,619 (+)EnsemblGRCm39 Ensembl
GRCm388122,775,470 - 122,817,887 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,775,486 - 122,817,880 (+)EnsemblGRCm38mm10GRCm38
MGSCv378125,299,405 - 125,341,781 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368125,666,626 - 125,703,971 (+)NCBIMGSCv36mm8
Celera8127,007,875 - 127,052,230 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map871.97NCBI
Acsf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,743,660 - 67,784,109 (+)NCBIGRCr8
mRatBN7.21950,835,116 - 50,875,557 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,835,221 - 50,875,553 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01955,594,801 - 55,635,312 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,594,831 - 55,635,122 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,302,623 - 66,342,436 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41953,066,291 - 53,106,673 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1950,073,106 - 50,113,121 (+)NCBICelera
Cytogenetic Map19q12NCBI
ACSF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,874,350 - 98,940,718 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,790,399 - 104,854,970 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,842,709 - 69,907,075 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,465,691 - 89,524,210 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,467,997 - 89,523,825 (+)Ensemblpanpan1.1panPan2
ACSF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,288,339 - 64,338,596 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,289,295 - 64,414,637 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha564,304,235 - 64,354,696 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0564,519,689 - 64,569,550 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,515,871 - 64,569,789 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,539,014 - 64,589,483 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,377,020 - 64,427,451 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0564,783,458 - 64,833,225 (-)NCBIUU_Cfam_GSD_1.0
Acsf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,946,656 - 24,983,470 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641700,187 - 736,941 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936641700,218 - 736,875 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACSF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6663,123 - 709,186 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16663,201 - 708,800 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26826,070 - 843,606 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACSF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,464,357 - 74,526,173 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,464,651 - 74,525,660 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660471,014,211 - 1,082,877 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acsf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746628,010 - 655,950 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624746627,089 - 655,922 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000004233   ⟹   ENSCLAP00000004152
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555412,837,448 - 2,876,316 (+)Ensembl
RefSeq Acc Id: XM_005411031   ⟹   XP_005411088
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555412,837,487 - 2,876,220 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507984   ⟹   XP_013363438
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555412,837,500 - 2,876,220 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507986   ⟹   XP_013363440
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555412,837,487 - 2,876,220 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005411088 (Get FASTA)   NCBI Sequence Viewer  
  XP_013363438 (Get FASTA)   NCBI Sequence Viewer  
  XP_013363440 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000004152
  ENSCLAP00000004152.1
Reference Protein Sequences
RefSeq Acc Id: XP_005411088   ⟸   XM_005411031
- Peptide Label: isoform X1
- UniProtKB: A0A8C2URE9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013363440   ⟸   XM_013507986
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013363438   ⟸   XM_013507984
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000004152   ⟸   ENSCLAT00000004233
Protein Domains
AMP-binding enzyme C-terminal   AMP-dependent synthetase/ligase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002959 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000004233 ENTREZGENE
  ENSCLAT00000004233.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.300.30 UniProtKB/TrEMBL
  3.40.50.12780 UniProtKB/TrEMBL
InterPro AMP-bd_C UniProtKB/TrEMBL
  AMP-bd_C_sf UniProtKB/TrEMBL
  AMP-binding_CS UniProtKB/TrEMBL
  AMP-dep_Synth/Lig UniProtKB/TrEMBL
  ANL_N_sf UniProtKB/TrEMBL
NCBI Gene Acsf3 ENTREZGENE
PANTHER ACYL-COA SYNTHETASE UniProtKB/TrEMBL
  FATTY ACID COA SYNTHETASE FAMILY UniProtKB/TrEMBL
Pfam AMP-binding UniProtKB/TrEMBL
  AMP-binding_C UniProtKB/TrEMBL
PROSITE AMP_BINDING UniProtKB/TrEMBL
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/TrEMBL
UniProt A0A8C2URE9 ENTREZGENE, UniProtKB/TrEMBL