Elmo1 (engulfment and cell motility 1) - Rat Genome Database

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Gene: Elmo1 (engulfment and cell motility 1) Heterocephalus glaber
Analyze
Symbol: Elmo1
Name: engulfment and cell motility 1
RGD ID: 18903389
Description: ENCODES a protein that exhibits guanyl nucleotide exchange factor activator activity (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament-based process (ortholog); phagocytosis (ortholog); ASSOCIATED WITH Diabetic Nephropathies (ortholog); esophagus adenocarcinoma (ortholog); Stevens-Johnson syndrome (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: engulfment and cell motility protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474023,881,197 - 24,353,526 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474023,776,788 - 24,354,682 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Elmo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474023,881,197 - 24,353,526 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474023,776,788 - 24,354,682 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
ELMO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38736,852,906 - 37,449,326 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl736,852,906 - 37,449,223 (-)Ensemblhg38GRCh38
GRCh37736,892,511 - 37,488,929 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36736,860,486 - 37,455,036 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34736,667,206 - 36,798,961NCBI
Celera736,878,399 - 37,472,945 (-)NCBICelera
Cytogenetic Map7p14.2-p14.1NCBI
HuRef736,771,444 - 37,368,496 (-)NCBIHuRef
CHM1_1736,891,996 - 37,488,280 (-)NCBICHM1_1
T2T-CHM13v2.0736,993,255 - 37,589,754 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2736,930,165 - 37,526,532 (-)NCBI
Elmo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391320,274,677 - 20,792,523 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1320,274,766 - 20,792,523 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381320,090,507 - 20,608,353 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1320,090,596 - 20,608,353 (+)Ensemblmm10GRCm38
MGSCv371320,277,294 - 20,698,394 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361320,192,890 - 20,613,990 (+)NCBIMGSCv36mm8
Celera1320,478,055 - 20,898,552 (+)NCBICelera
Cytogenetic Map13A2NCBI
cM Map137.21NCBI
Elmo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81748,982,188 - 49,518,525 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1748,982,188 - 49,518,159 (-)EnsemblGRCr8
mRatBN7.21744,286,495 - 44,822,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1744,286,485 - 44,822,788 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1746,357,453 - 46,881,045 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01751,116,592 - 51,640,189 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01745,608,016 - 46,130,585 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01746,352,102 - 46,888,788 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1746,353,330 - 46,794,845 (-)Ensemblrn6Rnor6.0
Rnor_5.01756,598,697 - 57,133,816 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41751,989,458 - 52,552,704 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1751,701,962 - 52,225,665 (+)NCBICelera
RGSC_v3.11751,992,297 - 52,462,470 (-)NCBI
Cytogenetic Map17q11NCBI
Elmo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554606,044,725 - 6,581,269 (+)Ensembl
ChiLan1.0NW_0049554606,044,827 - 6,580,770 (+)NCBIChiLan1.0ChiLan1.0
ELMO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2641,692,166 - 42,283,854 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1790,016,901 - 90,608,596 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0737,493,854 - 38,085,555 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1737,720,589 - 38,310,917 (-)NCBIPanPan1.1PanPan1.1panPan2
ELMO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11448,163,218 - 48,610,626 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1448,164,049 - 48,730,248 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1447,606,767 - 48,132,630 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01448,104,763 - 48,631,432 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1448,104,765 - 48,631,965 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11448,210,909 - 48,736,343 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01447,890,268 - 48,416,690 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01448,267,197 - 48,792,889 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Elmo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511893,096,524 - 93,647,112 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647812,306,450 - 12,754,963 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647812,308,255 - 12,754,957 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELMO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1836,786,378 - 37,347,283 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11836,755,026 - 37,336,095 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21840,536,457 - 40,984,221 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ELMO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12121,066,910 - 21,639,149 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2121,066,924 - 21,640,705 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666062694,803 - 1,273,767 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elmo1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11439,133,130 - 39,662,452 (-)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004840282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004840283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004840284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021254578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021254579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021254580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021254581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021254582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01018431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01018432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01018433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01018434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01018435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01018436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01018437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01018438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01018439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01018440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01018441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01018442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01002577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000011550   ⟹   ENSHGLP00000011423
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474023,881,197 - 24,353,526 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000011551   ⟹   ENSHGLP00000011424
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474023,881,534 - 24,353,526 (+)Ensembl
RefSeq Acc Id: XM_004840282   ⟹   XP_004840339
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474023,776,788 - 24,353,526 (+)NCBI
RefSeq Acc Id: XM_004840283   ⟹   XP_004840340
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474023,776,788 - 24,353,526 (+)NCBI
RefSeq Acc Id: XM_004840284   ⟹   XP_004840341
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474023,777,191 - 24,353,526 (+)NCBI
RefSeq Acc Id: XM_021254578   ⟹   XP_021110237
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474023,881,236 - 24,353,526 (+)NCBI
RefSeq Acc Id: XM_021254579   ⟹   XP_021110238
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474023,777,194 - 24,354,682 (+)NCBI
RefSeq Acc Id: XM_021254580   ⟹   XP_021110239
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474023,777,192 - 24,353,526 (+)NCBI
RefSeq Acc Id: XM_021254581   ⟹   XP_021110240
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474023,881,534 - 24,353,526 (+)NCBI
RefSeq Acc Id: XM_021254582   ⟹   XP_021110241
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474024,018,950 - 24,354,682 (+)NCBI
RefSeq Acc Id: XP_004840339   ⟸   XM_004840282
- Peptide Label: isoform X1
- UniProtKB: A0AAX6NZ76 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840340   ⟸   XM_004840283
- Peptide Label: isoform X1
- UniProtKB: A0AAX6NZ76 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840341   ⟸   XM_004840284
- Peptide Label: isoform X1
- UniProtKB: A0AAX6NZ76 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110239   ⟸   XM_021254580
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JBB6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110238   ⟸   XM_021254579
- Peptide Label: isoform X1
- UniProtKB: A0AAX6NZ76 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110237   ⟸   XM_021254578
- Peptide Label: isoform X1
- UniProtKB: A0AAX6NZ76 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110240   ⟸   XM_021254581
- Peptide Label: isoform X3
- UniProtKB: A0AAX6SP73 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110241   ⟸   XM_021254582
- Peptide Label: isoform X4
- UniProtKB: A0AAX6SP04 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000011424   ⟸   ENSHGLT00000011551
Ensembl Acc Id: ENSHGLP00000011423   ⟸   ENSHGLT00000011550


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008190 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000011550 ENTREZGENE
  ENSHGLT00000011551 ENTREZGENE
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  6.10.250.810 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  DUF3361 UniProtKB/TrEMBL
  ELMO_dom UniProtKB/TrEMBL
  ELMO_domain-containing UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
KEGG Report hgl:101716556 UniProtKB/TrEMBL
NCBI Gene Elmo1 ENTREZGENE
PANTHER ENGULFMENT AND CELL MOTILITY UniProtKB/TrEMBL
  PTHR12771:SF23 UniProtKB/TrEMBL
Pfam DUF3361 UniProtKB/TrEMBL
  ELMO_CED12 UniProtKB/TrEMBL
  PH_12 UniProtKB/TrEMBL
PROSITE ELMO UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A0A0P6JBB6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NZ76 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SP04 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SP73 ENTREZGENE, UniProtKB/TrEMBL