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Gene: ELMO1 (engulfment and cell motility 1) Homo sapiens
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Symbol: ELMO1
Name: engulfment and cell motility 1
Description: Exhibits SH3 domain binding activity. Contributes to guanyl-nucleotide exchange factor activity. Involved in several processes, including Rac protein signal transduction; actin cytoskeleton organization; and phagocytosis, engulfment. Localizes to the cytoplasm; guanyl-nucleotide exchange factor complex; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CED-12; ced-12 homolog 1; CED12; ELMO-1; engulfment and cell motility 1 (ced-12 homolog, c. elegans); engulfment and cell motility protein 1; KIAA0281; MGC126406; protein ced-12 homolog
Orthologs:
Mus musculus (house mouse) : Elmo1 (engulfment and cell motility 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Elmo1 (engulfment and cell motility 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Elmo1 (engulfment and cell motility 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ELMO1 (engulfment and cell motility 1)
Canis lupus familiaris (dog) : ELMO1 (engulfment and cell motility 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Elmo1 (engulfment and cell motility 1)
Sus scrofa (pig) : ELMO1 (engulfment and cell motility 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl736,854,361 - 37,449,249 (-)Ensembl
GRCh38736,852,906 - 37,449,326 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37736,892,511 - 37,488,895 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36736,860,486 - 37,455,036 (-)NCBINCBI36hg18NCBI36
Build 34736,667,206 - 36,798,961NCBI
Celera736,878,399 - 37,472,945 (-)NCBI
Cytogenetic Map7p14.2-p14.1NCBI
HuRef736,771,444 - 37,368,496 (-)NCBIHuRef
CHM1_1736,891,996 - 37,488,314 (-)NCBICHM1_1
CRA_TCAGchr7v2736,930,165 - 37,526,532 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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RNA-SEQ Expression

Sequence

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Additional Information

External Database Links
 
More on ELMO1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317811
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.