STIM2 (stromal interaction molecule 2) - Rat Genome Database

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Pathways
Gene: STIM2 (stromal interaction molecule 2) Chlorocebus sabaeus
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Symbol: STIM2
Name: stromal interaction molecule 2
RGD ID: 18377811
Description: ENCODES a protein that exhibits calcium channel regulator activity (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); gene expression (ortholog); protein catabolic process (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Weight Gain (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12723,330,382 - 23,498,965 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2723,332,789 - 23,498,829 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604769,841,556 - 70,006,138 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Weight Gain  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
STIM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12723,330,382 - 23,498,965 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2723,332,789 - 23,498,829 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604769,841,556 - 70,006,138 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
STIM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38426,860,841 - 27,025,381 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl426,857,601 - 27,025,381 (+)Ensemblhg38GRCh38
GRCh37426,862,463 - 27,027,003 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36426,471,462 - 26,634,907 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34426,538,581 - 26,703,272NCBI
Celera427,312,306 - 27,476,220 (+)NCBICelera
Cytogenetic Map4p15.2NCBI
HuRef426,200,122 - 26,364,764 (+)NCBIHuRef
CHM1_1426,863,824 - 27,028,520 (+)NCBICHM1_1
T2T-CHM13v2.0426,845,953 - 27,010,482 (+)NCBIT2T-CHM13v2.0
Stim2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39554,155,865 - 54,278,399 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl554,155,841 - 54,278,399 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38553,998,523 - 54,121,057 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl553,998,499 - 54,121,057 (+)Ensemblmm10GRCm38
MGSCv37554,389,762 - 54,512,296 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36554,286,771 - 54,408,451 (+)NCBIMGSCv36mm8
Celera551,381,922 - 51,504,557 (+)NCBICelera
Cytogenetic Map5C1NCBI
cM Map529.69NCBI
Stim2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81461,091,550 - 61,217,281 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1461,091,550 - 61,217,080 (-)EnsemblGRCr8
mRatBN7.21456,878,428 - 57,004,405 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1456,878,645 - 57,004,179 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1461,285,454 - 61,411,071 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01462,587,988 - 62,713,625 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01458,984,779 - 59,110,410 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1461,646,011 - 61,771,655 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1460,275,826 - 60,401,466 (-)NCBILyon_Normotensive
Lyon_Hypertensive1461,793,635 - 61,919,269 (-)NCBILyon_Hypertensive
F344_StmMcwi1460,722,306 - 60,847,943 (-)NCBIF344_StmMcwi
Rnor_6.01459,198,180 - 59,323,947 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1459,198,401 - 59,323,947 (-)Ensemblrn6Rnor6.0
Rnor_5.01459,325,608 - 59,451,210 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41461,630,737 - 61,759,846 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1455,989,151 - 56,113,547 (-)NCBICelera
RGSC_v3.11461,634,362 - 61,762,383 (-)NCBI
Cytogenetic Map14q11NCBI
Stim2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544318,278,464 - 18,366,522 (-)Ensembl
ChiLan1.0NW_00495544318,281,245 - 18,424,750 (-)NCBIChiLan1.0ChiLan1.0
STIM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2327,116,068 - 27,277,399 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1427,308,509 - 27,469,818 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0421,262,272 - 21,424,944 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1426,523,195 - 26,695,611 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl426,537,703 - 26,694,416 (+)EnsemblpanPan2panpan1.1
STIM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1383,560,690 - 83,703,978 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl383,564,108 - 83,724,520 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha386,073,946 - 86,216,661 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0384,529,366 - 84,672,425 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl384,531,617 - 84,692,965 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1383,653,235 - 83,796,214 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0383,773,498 - 83,915,775 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0384,154,006 - 84,297,027 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Stim2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528549,121,755 - 49,291,501 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364772,825,676 - 2,928,269 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364772,824,720 - 2,950,069 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STIM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl820,517,587 - 20,604,319 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1820,456,343 - 20,609,283 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2821,074,680 - 21,104,211 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Stim2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247555,601,364 - 5,762,516 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247555,600,929 - 5,765,675 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Stim2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11152,017,754 - 52,153,977 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in STIM2
2727 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000014821   ⟹   ENSCSAP00000012782
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2723,332,789 - 23,498,829 (-)Ensembl
RefSeq Acc Id: XM_008017696   ⟹   XP_008015887
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12723,330,382 - 23,498,965 (-)NCBI
Vero_WHO_p1.0NW_02366604769,841,556 - 70,006,120 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008017697   ⟹   XP_008015888
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12723,330,382 - 23,498,965 (-)NCBI
Vero_WHO_p1.0NW_02366604769,841,556 - 70,006,138 (-)NCBI
Sequence:
RefSeq Acc Id: XR_502325
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12723,330,543 - 23,498,797 (-)NCBI
Vero_WHO_p1.0NW_02366604769,841,556 - 70,006,120 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008015887 (Get FASTA)   NCBI Sequence Viewer  
  XP_008015888 (Get FASTA)   NCBI Sequence Viewer  
  XP_072868579 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012782
  ENSCSAP00000012782.1
RefSeq Acc Id: XP_008015888   ⟸   XM_008017697
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RVZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008015887   ⟸   XM_008017696
- Peptide Label: isoform X1
Ensembl Acc Id: ENSCSAP00000012782   ⟸   ENSCSAT00000014821


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016726 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014821.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  1.10.238.180 UniProtKB/TrEMBL
  1.10.287.3550 UniProtKB/TrEMBL
  1.20.5.340 UniProtKB/TrEMBL
InterPro SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  SOAR UniProtKB/TrEMBL
  STIM UniProtKB/TrEMBL
  STIM2_SAM UniProtKB/TrEMBL
NCBI Gene STIM2 ENTREZGENE
PANTHER PTHR15136 UniProtKB/TrEMBL
  STROMAL INTERACTION MOLECULE 2 UniProtKB/TrEMBL
Pfam EF-hand_STIM1 UniProtKB/TrEMBL
  SAM_2 UniProtKB/TrEMBL
  SOAR UniProtKB/TrEMBL
PROSITE SAM_DOMAIN UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
UniProt A0A0D9RVZ3 ENTREZGENE, UniProtKB/TrEMBL