Zfp418l1 (zinc finger protein 418 like 1) - Rat Genome Database

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Gene: Zfp418l1 (zinc finger protein 418 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Zfp418l1
Name: zinc finger protein 418 like 1
RGD ID: 1587451
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC691135; similar to zinc finger protein 418; zinc finger protein 271-like; zinc finger protein 418-like; zinc finger protein 883-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8175,671,211 - 75,684,615 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl175,671,227 - 75,690,365 (+)EnsemblGRCr8
mRatBN7.2166,638,112 - 66,649,875 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,638,117 - 66,656,976 (+)EnsemblmRatBN7.2
Rnor_6.0169,672,957 - 69,684,113 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0171,069,953 - 71,082,872 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4165,035,840 - 65,047,575 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera164,393,602 - 64,405,378 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Zfp418l1
162 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat

Markers in Region
RH130850  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2166,592,255 - 66,592,458 (+)MAPPERmRatBN7.2
Rnor_6.0169,685,495 - 69,685,697NCBIRnor6.0
Rnor_6.0169,628,006 - 69,628,208NCBIRnor6.0
Rnor_5.0171,082,470 - 71,082,672UniSTSRnor5.0
Rnor_5.0171,024,981 - 71,025,183UniSTSRnor5.0
RGSC_v3.4164,989,262 - 64,989,464UniSTSRGSC3.4
RGSC_v3.4165,047,747 - 65,047,946UniSTSRGSC3.4
Celera164,347,687 - 64,347,889UniSTS
Celera164,405,550 - 64,405,749UniSTS
RH 3.4 Map1742.4UniSTS
Cytogenetic Map1q12UniSTS
RH131093  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2166,590,330 - 66,590,530 (+)MAPPERmRatBN7.2
mRatBN7.2166,646,782 - 66,646,982 (+)MAPPERmRatBN7.2
Rnor_6.0169,681,639 - 69,681,838NCBIRnor6.0
Rnor_6.0169,626,081 - 69,626,280NCBIRnor6.0
Rnor_5.0171,078,614 - 71,078,813UniSTSRnor5.0
Rnor_5.0171,023,056 - 71,023,255UniSTSRnor5.0
RGSC_v3.4164,987,337 - 64,987,536UniSTSRGSC3.4
RGSC_v3.4165,044,483 - 65,044,682UniSTSRGSC3.4
Celera164,402,286 - 64,402,485UniSTS
Celera164,345,762 - 64,345,961UniSTS
RH 3.4 Map1742.2UniSTS
Cytogenetic Map1q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 48 58 128 86 11 47 35 32 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000094686   ⟹   ENSRNOP00000078413
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,671,234 - 75,690,365 (+)Ensembl
mRatBN7.2 Ensembl166,638,127 - 66,650,444 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119109   ⟹   ENSRNOP00000087511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,671,227 - 75,690,365 (+)Ensembl
mRatBN7.2 Ensembl166,638,117 - 66,656,976 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000166560   ⟹   ENSRNOP00000107964
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl175,671,290 - 75,683,397 (+)Ensembl
RefSeq Acc Id: XM_008759083   ⟹   XP_008757305
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,671,211 - 75,684,615 (+)NCBI
mRatBN7.2166,638,112 - 66,649,422 (+)NCBI
Rnor_6.0169,672,957 - 69,684,113 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039100457   ⟹   XP_038956385
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,671,229 - 75,684,615 (+)NCBI
mRatBN7.2166,638,112 - 66,649,422 (+)NCBI
RefSeq Acc Id: XM_039100458   ⟹   XP_038956386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,671,229 - 75,684,615 (+)NCBI
mRatBN7.2166,638,112 - 66,649,422 (+)NCBI
RefSeq Acc Id: XM_039100461   ⟹   XP_038956389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8175,671,229 - 75,684,615 (+)NCBI
mRatBN7.2166,638,112 - 66,649,875 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008757305 (Get FASTA)   NCBI Sequence Viewer  
  XP_038956385 (Get FASTA)   NCBI Sequence Viewer  
  XP_038956386 (Get FASTA)   NCBI Sequence Viewer  
  XP_038956389 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000078413.2
  ENSRNOP00000087511.2
  ENSRNOP00000107964.1
RefSeq Acc Id: XP_008757305   ⟸   XM_008759083
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A7D0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038956389   ⟸   XM_039100461
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038956386   ⟸   XM_039100458
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038956385   ⟸   XM_039100457
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZKX0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000087511   ⟸   ENSRNOT00000119109
Ensembl Acc Id: ENSRNOP00000078413   ⟸   ENSRNOT00000094686
Ensembl Acc Id: ENSRNOP00000107964   ⟸   ENSRNOT00000166560

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1587451 AgrOrtholog
BioCyc Gene G2FUF-60971 BioCyc
Ensembl Genes ENSRNOG00000066094 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000094686.2 UniProtKB/TrEMBL
  ENSRNOT00000119109.2 UniProtKB/TrEMBL
  ENSRNOT00000166560.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene 691135 ENTREZGENE
PANTHER ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 771 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp418l1 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000066094 RatGTEx
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8I5ZKX0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A7D0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LWP6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Zfp418l1  zinc finger protein 418 like 1  LOC691135  similar to zinc finger protein 418  Symbol and Name Changed 1299863 APPROVED
2006-11-19 LOC691135  similar to zinc finger protein 418      Symbol and Name status set to provisional 70820 PROVISIONAL