Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mmgt1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Mmgt1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of MMGT1 mRNA] | CTD | PMID:22206623 | Mmgt1 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Mmgt1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of MMGT1 mRNA | CTD | PMID:22206623 | Mmgt1 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of MMGT1 mRNA | CTD | PMID:29097150 | Mmgt1 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:27291303 more ... | Mmgt1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Mmgt1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MMGT1 mRNA | CTD | PMID:19465110 and PMID:28213091 | Mmgt1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MMGT1 mRNA | CTD | PMID:33387578 | Mmgt1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Mmgt1 (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of MMGT1 mRNA | CTD | PMID:25975270 | Mmgt1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Mmgt1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of MMGT1 mRNA | CTD | PMID:21570461 | Mmgt1 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Mmgt1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of MMGT1 mRNA | CTD | PMID:20188158 | Mmgt1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | MMGT1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MMGT1 mRNA | CTD | PMID:28628672 | Mmgt1 | Rat | all-trans-retinoic acid | decreases expression | ISO | MMGT1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of MMGT1 mRNA | CTD | PMID:33167477 | Mmgt1 | Rat | benzo[a]pyrene | increases expression | ISO | Mmgt1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of MMGT1 mRNA | CTD | PMID:22228805 | Mmgt1 | Rat | benzo[a]pyrene | affects methylation | ISO | MMGT1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MMGT1 exon and Benzo(a)pyrene affects the methylation of MMGT1 promoter | CTD | PMID:27901495 | Mmgt1 | Rat | benzo[a]pyrene | decreases methylation | ISO | MMGT1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of MMGT1 3' UTR | CTD | PMID:27901495 | Mmgt1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of MMGT1 mRNA | CTD | PMID:25181051 | Mmgt1 | Rat | bisphenol F | multiple interactions | ISO | MMGT1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MMGT1 mRNA | CTD | PMID:28628672 | Mmgt1 | Rat | caffeine | decreases phosphorylation | ISO | MMGT1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of MMGT1 protein | CTD | PMID:35688186 | Mmgt1 | Rat | carbon nanotube | decreases expression | ISO | Mmgt1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of MMGT1 mRNA | CTD | PMID:25554681 | Mmgt1 | Rat | choline | multiple interactions | ISO | Mmgt1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MMGT1 gene | CTD | PMID:20938992 | Mmgt1 | Rat | chrysene | decreases expression | ISO | Mmgt1 (Mus musculus) | 6480464 | chrysene results in decreased expression of MMGT1 mRNA | CTD | PMID:26377693 | Mmgt1 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of MMGT1 mRNA | CTD | PMID:26577399 | Mmgt1 | Rat | cyclosporin A | increases expression | ISO | MMGT1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of MMGT1 mRNA | CTD | PMID:25562108 | Mmgt1 | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of MMGT1 mRNA | CTD | PMID:32679240 | Mmgt1 | Rat | dexamethasone | multiple interactions | ISO | MMGT1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MMGT1 mRNA | CTD | PMID:28628672 | Mmgt1 | Rat | dibenzo[a,l]pyrene | decreases expression | ISO | Mmgt1 (Mus musculus) | 6480464 | dibenzo(a and l)pyrene results in decreased expression of MMGT1 mRNA | CTD | PMID:25908611 | Mmgt1 | Rat | diethylstilbestrol | decreases expression | EXP | | 6480464 | Diethylstilbestrol results in decreased expression of MMGT1 mRNA | CTD | PMID:36653537 | Mmgt1 | Rat | doxorubicin | decreases expression | ISO | MMGT1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of MMGT1 mRNA | CTD | PMID:29803840 | Mmgt1 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of MMGT1 mRNA | CTD | PMID:24136188 | Mmgt1 | Rat | folic acid | multiple interactions | ISO | Mmgt1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MMGT1 gene more ... | CTD | PMID:20938992 and PMID:22206623 | Mmgt1 | Rat | FR900359 | decreases phosphorylation | ISO | MMGT1 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of MMGT1 protein | CTD | PMID:37730182 | Mmgt1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of MMGT1 mRNA | CTD | PMID:22061828 | Mmgt1 | Rat | gold atom | decreases expression | ISO | MMGT1 (Homo sapiens) | 6480464 | Gold results in decreased expression of MMGT1 mRNA | CTD | PMID:25523186 | Mmgt1 | Rat | gold(0) | decreases expression | ISO | MMGT1 (Homo sapiens) | 6480464 | Gold results in decreased expression of MMGT1 mRNA | CTD | PMID:25523186 | Mmgt1 | Rat | hydroquinone O-beta-D-glucopyranoside | increases expression | ISO | MMGT1 (Homo sapiens) | 6480464 | Arbutin results in increased expression of MMGT1 mRNA | CTD | PMID:17103032 | Mmgt1 | Rat | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of MMGT1 mRNA | CTD | PMID:22129741 | Mmgt1 | Rat | indometacin | multiple interactions | ISO | MMGT1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MMGT1 mRNA | CTD | PMID:28628672 | Mmgt1 | Rat | ivermectin | decreases expression | ISO | MMGT1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of MMGT1 protein | CTD | PMID:32959892 | Mmgt1 | Rat | L-methionine | multiple interactions | ISO | Mmgt1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MMGT1 gene | CTD | PMID:20938992 | Mmgt1 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of MMGT1 mRNA | CTD | PMID:30467583 | Mmgt1 | Rat | microcystin-LR | decreases expression | ISO | Mmgt1 (Mus musculus) | 6480464 | cyanoginosin LR results in decreased expression of MMGT1 protein | CTD | PMID:26984711 | Mmgt1 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of MMGT1 mRNA | CTD | PMID:22129741 | Mmgt1 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of MMGT1 mRNA | CTD | PMID:24136188 | Mmgt1 | Rat | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of MMGT1 mRNA | CTD | PMID:24136188 | Mmgt1 | Rat | ozone | multiple interactions | ISO | Mmgt1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of MMGT1 mRNA | CTD | PMID:34911549 | Mmgt1 | Rat | paracetamol | affects expression | ISO | Mmgt1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of MMGT1 mRNA | CTD | PMID:17562736 | Mmgt1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of MMGT1 mRNA | CTD | PMID:33387578 | Mmgt1 | Rat | pirinixic acid | increases expression | ISO | Mmgt1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of MMGT1 mRNA | CTD | PMID:23811191 | Mmgt1 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of MMGT1 mRNA | CTD | PMID:28374803 | Mmgt1 | Rat | sodium arsenite | increases expression | ISO | MMGT1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of MMGT1 mRNA | CTD | PMID:38568856 | Mmgt1 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of MMGT1 mRNA | CTD | PMID:33387578 | Mmgt1 | Rat | titanium dioxide | decreases expression | ISO | Mmgt1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of MMGT1 mRNA | CTD | PMID:23557971 | Mmgt1 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of MMGT1 mRNA | CTD | PMID:30589522 | Mmgt1 | Rat | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of MMGT1 mRNA | CTD | PMID:24136188 | |