Map7d2 (MAP7 domain containing 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Map7d2 (MAP7 domain containing 2) Rattus norvegicus
Analyze
Symbol: Map7d2
Name: MAP7 domain containing 2
RGD ID: 1564852
Description: Predicted to be involved in microtubule cytoskeleton organization. Predicted to be active in microtubule cytoskeleton. Orthologous to human MAP7D2 (MAP7 domain containing 2); INTERACTS WITH bisphenol A; Brodifacoum; fenvalerate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: brain-enriched E-MAP-115-like protein; Brelin; LOC317508; MAP7 domain-containing protein 2; Mtap7d2; RGD1564852; similar to hypothetical protein FLJ14503
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X39,181,091 - 39,296,814 (-)NCBIGRCr8
mRatBN7.2X35,372,453 - 35,488,073 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX35,372,700 - 35,488,091 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX36,514,297 - 36,625,464 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X39,977,937 - 40,089,108 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X35,143,980 - 35,255,149 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X38,400,578 - 38,467,825 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX38,397,261 - 38,468,360 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X38,706,546 - 38,777,123 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X56,573,552 - 56,689,427 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX36,028,803 - 36,139,227 (-)NCBICelera
Cytogenetic MapXq14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:24625528  


Genomics

Comparative Map Data
Map7d2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X39,181,091 - 39,296,814 (-)NCBIGRCr8
mRatBN7.2X35,372,453 - 35,488,073 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX35,372,700 - 35,488,091 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX36,514,297 - 36,625,464 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X39,977,937 - 40,089,108 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X35,143,980 - 35,255,149 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X38,400,578 - 38,467,825 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX38,397,261 - 38,468,360 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X38,706,546 - 38,777,123 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X56,573,552 - 56,689,427 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX36,028,803 - 36,139,227 (-)NCBICelera
Cytogenetic MapXq14NCBI
MAP7D2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X20,006,713 - 20,116,907 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX20,006,713 - 20,116,907 (-)EnsemblGRCh38hg38GRCh38
GRCh37X20,024,831 - 20,135,025 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X19,935,150 - 20,044,937 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX24,148,899 - 24,259,048 (-)NCBICelera
Cytogenetic MapXp22.12NCBI
HuRefX17,770,131 - 17,877,650 (-)NCBIHuRef
CHM1_1X20,055,334 - 20,165,529 (-)NCBICHM1_1
T2T-CHM13v2.0X19,589,600 - 19,699,784 (-)NCBIT2T-CHM13v2.0
Map7d2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X158,197,488 - 158,281,954 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX158,197,568 - 158,281,753 (+)EnsemblGRCm39 Ensembl
GRCm38X159,414,492 - 159,498,958 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX159,414,572 - 159,498,757 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X155,852,510 - 155,936,879 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X154,758,683 - 154,843,052 (+)NCBIMGSCv36mm8
CeleraX142,661,499 - 142,746,251 (+)NCBICelera
Cytogenetic MapXF4NCBI
cM MapX73.45NCBI
Map7d2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955509450,486 - 494,290 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955509447,053 - 568,590 (-)NCBIChiLan1.0ChiLan1.0
MAP7D2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X21,802,994 - 21,914,412 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X21,806,381 - 21,917,800 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X12,624,994 - 12,736,318 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X19,985,121 - 20,096,303 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX19,989,048 - 20,096,192 (-)Ensemblpanpan1.1panPan2
MAP7D2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X15,916,609 - 15,972,552 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX15,917,978 - 15,971,000 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X15,875,385 - 15,983,930 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX15,875,626 - 15,983,901 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X15,925,054 - 16,033,552 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X15,932,874 - 16,041,328 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X15,994,670 - 16,103,414 (-)NCBIUU_Cfam_GSD_1.0
Map7d2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X9,007,408 - 9,119,000 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366244,087,099 - 4,147,167 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366244,038,854 - 4,150,495 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAP7D2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX16,327,968 - 16,422,772 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X16,327,718 - 16,423,546 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X17,593,326 - 17,690,207 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAP7D2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X18,474,073 - 18,583,545 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX18,473,803 - 18,583,523 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605620,329,801 - 20,440,783 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Map7d2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248294,825,277 - 4,884,460 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248294,821,828 - 4,948,202 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Map7d2
427 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:843
Count of miRNA genes:307
Interacting mature miRNAs:408
Transcripts:ENSRNOT00000007524, ENSRNOT00000045285
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598873Memor2Memory QTL 22.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)X2099094741052531Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
2290375Gluco34Glucose level QTL 342.75blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X2099094741203591Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat

Markers in Region
BF398264  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X35,389,501 - 35,389,748 (+)MAPPERmRatBN7.2
Rnor_6.0X38,414,310 - 38,414,556NCBIRnor6.0
Rnor_5.0X38,723,592 - 38,723,838UniSTSRnor5.0
RGSC_v3.4X56,590,595 - 56,590,841UniSTSRGSC3.4
CeleraX36,042,536 - 36,042,782UniSTS
RH 3.4 MapX504.1UniSTS
Cytogenetic MapXq21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 82 81 50 25 50 6 209 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000045285   ⟹   ENSRNOP00000042347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX35,372,700 - 35,488,091 (-)Ensembl
Rnor_6.0 EnsemblX38,397,261 - 38,468,360 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108099   ⟹   ENSRNOP00000077197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX35,372,700 - 35,488,091 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110899   ⟹   ENSRNOP00000086855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX35,372,700 - 35,488,091 (-)Ensembl
RefSeq Acc Id: NM_001289778   ⟹   NP_001276707
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X39,181,091 - 39,296,695 (-)NCBI
mRatBN7.2X35,372,459 - 35,488,072 (-)NCBI
Rnor_6.0X38,400,578 - 38,467,825 (-)NCBI
CeleraX36,028,803 - 36,139,227 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099842   ⟹   XP_038955770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X39,181,327 - 39,296,699 (-)NCBI
mRatBN7.2X35,372,453 - 35,488,073 (-)NCBI
RefSeq Acc Id: XM_039099843   ⟹   XP_038955771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X39,181,327 - 39,296,814 (-)NCBI
mRatBN7.2X35,372,453 - 35,488,072 (-)NCBI
RefSeq Acc Id: XM_039099844   ⟹   XP_038955772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X39,181,327 - 39,296,754 (-)NCBI
mRatBN7.2X35,372,453 - 35,488,073 (-)NCBI
RefSeq Acc Id: NP_001276707   ⟸   NM_001289778
- UniProtKB: W0T3G7 (UniProtKB/TrEMBL),   D4A4L4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000042347   ⟸   ENSRNOT00000045285
RefSeq Acc Id: XP_038955772   ⟸   XM_039099844
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038955770   ⟸   XM_039099842
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A4J6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955771   ⟸   XM_039099843
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZJE8 (UniProtKB/TrEMBL),   A6IPN0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000086855   ⟸   ENSRNOT00000110899
Ensembl Acc Id: ENSRNOP00000077197   ⟸   ENSRNOT00000108099

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4L4-F1-model_v2 AlphaFold D4A4L4 1-715 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564852 AgrOrtholog
BioCyc Gene G2FUF-2486 BioCyc
Ensembl Genes ENSRNOG00000005176 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045285.7 UniProtKB/TrEMBL
  ENSRNOT00000108099.1 UniProtKB/TrEMBL
  ENSRNOT00000110899.1 UniProtKB/TrEMBL
InterPro E-MAP-115 UniProtKB/TrEMBL
  MAP7_domain-containing UniProtKB/TrEMBL
KEGG Report rno:317508 UniProtKB/TrEMBL
NCBI Gene 317508 ENTREZGENE
PANTHER MAP7 DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  MICROTUBULE-ASSOCIATED PROTEIN UniProtKB/TrEMBL
Pfam MAP7 UniProtKB/TrEMBL
PhenoGen Map7d2 PhenoGen
RatGTEx ENSRNOG00000005176 RatGTEx
UniProt A0A8I5ZJE8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A4J6 ENTREZGENE, UniProtKB/TrEMBL
  A6IPN0 ENTREZGENE, UniProtKB/TrEMBL
  D4A4L4 ENTREZGENE, UniProtKB/TrEMBL
  W0T3G7 ENTREZGENE
UniProt Secondary W0T3G7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-08-29 Map7d2  MAP7 domain containing 2  Mtap7d2  MAP7 domain containing 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Mtap7d2  MAP7 domain containing 2  RGD1564852_predicted  similar to hypothetical protein FLJ14503 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564852_predicted  similar to hypothetical protein FLJ14503 (predicted)  LOC317508  similar to hypothetical protein FLJ14503  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC317508  similar to hypothetical protein FLJ14503      Symbol and Name status set to provisional 70820 PROVISIONAL