Trank1 (tetratricopeptide repeat and ankyrin repeat containing 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways
Gene: Trank1 (tetratricopeptide repeat and ankyrin repeat containing 1) Rattus norvegicus
Analyze
Symbol: Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
RGD ID: 1563130
Description: Orthologous to human TRANK1 (tetratricopeptide repeat and ankyrin repeat containing 1); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; dimethylarsinic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC316022; RGD1563130; similar to KIAA0342 protein; TPR and ankyrin repeat-containing protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88120,153,381 - 120,233,879 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8120,154,362 - 120,234,087 (+)EnsemblGRCr8
mRatBN7.28111,275,973 - 111,355,491 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8111,276,354 - 111,355,092 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8116,892,440 - 116,970,177 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08115,091,671 - 115,169,416 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08112,934,500 - 113,012,248 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08119,566,509 - 119,644,249 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,566,509 - 119,644,249 (+)Ensemblrn6Rnor6.0
Rnor_5.08118,916,156 - 118,993,803 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48115,701,554 - 115,781,013 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8110,557,993 - 110,635,930 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Trank1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88120,153,381 - 120,233,879 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8120,154,362 - 120,234,087 (+)EnsemblGRCr8
mRatBN7.28111,275,973 - 111,355,491 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8111,276,354 - 111,355,092 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8116,892,440 - 116,970,177 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08115,091,671 - 115,169,416 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08112,934,500 - 113,012,248 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08119,566,509 - 119,644,249 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,566,509 - 119,644,249 (+)Ensemblrn6Rnor6.0
Rnor_5.08118,916,156 - 118,993,803 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48115,701,554 - 115,781,013 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8110,557,993 - 110,635,930 (+)NCBICelera
Cytogenetic Map8q32NCBI
TRANK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38336,826,819 - 36,945,744 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl336,826,817 - 36,945,057 (-)Ensemblhg38GRCh38
GRCh37336,868,310 - 36,986,545 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36336,843,315 - 36,877,415 (-)NCBIBuild 36Build 36hg18NCBI36
Celera336,811,078 - 36,929,308 (-)NCBICelera
Cytogenetic Map3p22.2NCBI
HuRef336,808,964 - 36,927,088 (-)NCBIHuRef
CHM1_1336,818,551 - 36,938,172 (-)NCBICHM1_1
T2T-CHM13v2.0336,828,168 - 36,947,110 (-)NCBIT2T-CHM13v2.0
Trank1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399111,140,351 - 111,224,843 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9111,140,807 - 111,224,843 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389111,311,283 - 111,395,775 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9111,311,739 - 111,395,775 (+)Ensemblmm10GRCm38
MGSCv379111,214,243 - 111,298,279 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369111,219,636 - 111,240,591 (+)NCBIMGSCv36mm8
Celera9111,038,156 - 111,123,540 (+)NCBICelera
Cytogenetic Map9F3NCBI
cM Map960.95NCBI
Trank1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554213,707,510 - 3,853,868 (-)Ensembl
ChiLan1.0NW_0049554213,707,510 - 3,852,886 (-)NCBIChiLan1.0ChiLan1.0
TRANK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2236,788,485 - 36,907,530 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1336,793,249 - 36,912,330 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0336,732,939 - 36,852,023 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1337,023,455 - 37,141,982 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl337,024,909 - 37,102,299 (-)EnsemblpanPan2panpan1.1
TRANK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1236,749,817 - 6,849,113 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl236,631,276 - 6,849,034 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha236,789,473 - 6,869,908 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0237,034,999 - 7,115,474 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl236,946,464 - 7,134,352 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1236,854,618 - 6,935,467 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0236,997,235 - 7,077,671 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0236,987,132 - 7,067,610 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Trank1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118193,265,171 - 193,365,150 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647326,403,681 - 26,482,721 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647326,403,786 - 26,481,284 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRANK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1321,938,966 - 22,023,156 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11321,913,400 - 22,023,165 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21323,906,064 - 23,912,672 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRANK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1152,464,289 - 2,583,314 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl152,502,023 - 2,581,141 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606311,201,749 - 11,319,415 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trank1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478814,922,497 - 15,065,624 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462478814,926,685 - 15,035,745 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Trank1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v18102,287,730 - 102,364,191 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Trank1
361 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:92
Interacting mature miRNAs:100
Transcripts:ENSRNOT00000028633
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH144141  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28111,284,724 - 111,284,860 (+)MAPPERmRatBN7.2
Rnor_6.08119,574,883 - 119,575,018NCBIRnor6.0
Rnor_5.08118,924,529 - 118,924,664UniSTSRnor5.0
RGSC_v3.48115,711,646 - 115,711,781UniSTSRGSC3.4
Celera8110,566,584 - 110,566,719UniSTS
RH 3.4 Map81191.6UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 154 80 79 48 30 48 6 280 129 10 133 79 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000028633   ⟹   ENSRNOP00000028633
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8120,154,438 - 120,233,879 (+)Ensembl
mRatBN7.2 Ensembl8111,276,354 - 111,355,092 (+)Ensembl
Rnor_6.0 Ensembl8119,566,509 - 119,644,249 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000122532   ⟹   ENSRNOP00000104428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8120,154,362 - 120,234,087 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000165486   ⟹   ENSRNOP00000110556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8120,154,380 - 120,233,879 (+)Ensembl
RefSeq Acc Id: NM_001191799   ⟹   NP_001178728
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88120,154,438 - 120,233,879 (+)NCBI
mRatBN7.28111,276,051 - 111,355,491 (+)NCBI
Rnor_6.08119,566,509 - 119,644,249 (+)NCBI
Rnor_5.08118,916,156 - 118,993,803 (+)NCBI
Celera8110,557,993 - 110,635,930 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039081614   ⟹   XP_038937542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88120,154,599 - 120,233,879 (+)NCBI
mRatBN7.28111,276,219 - 111,355,491 (+)NCBI
RefSeq Acc Id: XM_039081615   ⟹   XP_038937543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88120,154,599 - 120,233,879 (+)NCBI
mRatBN7.28111,276,219 - 111,355,491 (+)NCBI
RefSeq Acc Id: XM_039081616   ⟹   XP_038937544
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88120,154,599 - 120,233,879 (+)NCBI
mRatBN7.28111,276,219 - 111,355,491 (+)NCBI
RefSeq Acc Id: XM_039081617   ⟹   XP_038937545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88120,154,599 - 120,233,879 (+)NCBI
mRatBN7.28111,276,219 - 111,355,491 (+)NCBI
RefSeq Acc Id: XM_039081618   ⟹   XP_038937546
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88120,153,381 - 120,233,879 (+)NCBI
mRatBN7.28111,275,973 - 111,355,491 (+)NCBI
RefSeq Acc Id: XR_005487854
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88120,154,597 - 120,222,884 (+)NCBI
mRatBN7.28111,276,219 - 111,344,608 (+)NCBI
RefSeq Acc Id: XR_005487855
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88120,154,597 - 120,222,884 (+)NCBI
mRatBN7.28111,276,219 - 111,344,496 (+)NCBI
RefSeq Acc Id: NP_001178728   ⟸   NM_001191799
- UniProtKB: D3ZSG2 (UniProtKB/TrEMBL),   A6I3J3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000028633   ⟸   ENSRNOT00000028633
RefSeq Acc Id: XP_038937546   ⟸   XM_039081618
- Peptide Label: isoform X5
- UniProtKB: A6I3J3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937542   ⟸   XM_039081614
- Peptide Label: isoform X1
- UniProtKB: A6I3J3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937545   ⟸   XM_039081617
- Peptide Label: isoform X4
- UniProtKB: A6I3J3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937543   ⟸   XM_039081615
- Peptide Label: isoform X2
- UniProtKB: A6I3J3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937544   ⟸   XM_039081616
- Peptide Label: isoform X3
- UniProtKB: A6I3J3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000110556   ⟸   ENSRNOT00000165486
Ensembl Acc Id: ENSRNOP00000104428   ⟸   ENSRNOT00000122532

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563130 AgrOrtholog
BioCyc Gene G2FUF-29021 BioCyc
Ensembl Genes ENSRNOG00000021091 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028633 ENTREZGENE
  ENSRNOT00000028633.7 UniProtKB/TrEMBL
  ENSRNOT00000122532.1 UniProtKB/TrEMBL
  ENSRNOT00000165486 ENTREZGENE
  ENSRNOT00000165486.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  TPR-like_helical UniProtKB/TrEMBL
  TRANK1 UniProtKB/TrEMBL
KEGG Report rno:316022 UniProtKB/TrEMBL
NCBI Gene 316022 ENTREZGENE
PANTHER PTHR21529 UniProtKB/TrEMBL
  TPR AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
PhenoGen Trank1 PhenoGen
PROSITE ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021091 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0ABK0LI25_RAT UniProtKB/TrEMBL
  A0ABK0LUU5_RAT UniProtKB/TrEMBL
  A6I3J3 ENTREZGENE, UniProtKB/TrEMBL
  D3ZSG2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Trank1  tetratricopeptide repeat and ankyrin repeat containing 1  RGD1563130  similar to KIAA0342 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1563130  similar to KIAA0342 protein   RGD1563130_predicted  similar to KIAA0342 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563130_predicted  similar to KIAA0342 protein (predicted)  LOC316022  similar to KIAA0342 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC316022  similar to KIAA0342 protein      Symbol and Name status set to provisional 70820 PROVISIONAL