CELA1 (chymotrypsin like elastase 1) - Rat Genome Database

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Gene: CELA1 (chymotrypsin like elastase 1) Sus scrofa
Analyze
Symbol: CELA1
Name: chymotrypsin like elastase 1
RGD ID: 14166479
Description: ENCODES a protein that exhibits serine-type endopeptidase activity (ortholog); INVOLVED IN digestive system development (ortholog); elastin catabolic process (ortholog); exocrine pancreas development (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN extracellular region (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: chymotrypsin like elastase family member 1; chymotrypsin-like elastase family member 1; ELA1; Elastase-1; ELS1; pancreatic elastase I
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.2517,250,142 - 17,279,128 (-)NCBISscrofa10.2Sscrofa10.2susScr3



References
Additional References at PubMed
PMID:628010   PMID:3528137   PMID:3648024   PMID:4578945   PMID:5415108   PMID:5415110   PMID:7922044   PMID:12189154   PMID:14681463   PMID:16321984   PMID:16488429   PMID:16511165  
PMID:17083959   PMID:17145712   PMID:17266656   PMID:19603802   PMID:20507992   PMID:22301074   PMID:26372354   PMID:30032202   PMID:33002681  


Genomics

Comparative Map Data
CELA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.2517,250,142 - 17,279,128 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CELA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381251,328,442 - 51,346,679 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1251,328,442 - 51,346,679 (-)Ensemblhg38GRCh38
GRCh371251,722,226 - 51,740,463 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361250,008,494 - 50,026,730 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341250,008,493 - 50,026,730NCBI
Celera1250,523,712 - 50,541,944 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1248,755,149 - 48,773,386 (-)NCBIHuRef
CHM1_11251,688,462 - 51,705,900 (-)NCBICHM1_1
T2T-CHM13v2.01251,291,249 - 51,309,485 (-)NCBIT2T-CHM13v2.0
Cela1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915100,572,303 - 100,585,801 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15100,572,302 - 100,585,802 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3815100,674,422 - 100,687,920 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15100,674,421 - 100,687,921 (-)Ensemblmm10GRCm38
MGSCv3715100,504,853 - 100,518,351 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3615100,502,459 - 100,515,952 (-)NCBIMGSCv36mm8
Celera15102,827,643 - 102,841,149 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.38NCBI
Cela1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87133,651,939 - 133,665,136 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7133,651,941 - 133,665,061 (-)EnsemblGRCr8
mRatBN7.27131,773,161 - 131,786,300 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7131,742,002 - 131,786,285 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7133,575,294 - 133,588,426 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07135,800,881 - 135,814,013 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07135,714,422 - 135,727,635 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd7135,734,888 - 135,748,005 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive7136,686,248 - 136,699,367 (-)NCBILyon_Normotensive
Lyon_Hypertensive7136,813,844 - 136,826,963 (-)NCBILyon_Hypertensive
F344_StmMcwi7135,258,007 - 135,271,124 (-)NCBIF344_StmMcwi
Rnor_6.07142,305,337 - 142,318,621 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7142,305,338 - 142,318,620 (-)Ensemblrn6Rnor6.0
Rnor_5.07140,110,478 - 140,123,423 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47139,439,589 - 139,452,717 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7128,249,427 - 128,262,461 (-)NCBICelera
RGSC_v3.17139,515,742 - 139,529,176 (-)NCBI
Cytogenetic Map7q36NCBI
Cela1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555471,810,670 - 1,824,409 (-)Ensembl
ChiLan1.0NW_0049555471,810,680 - 1,823,938 (-)NCBIChiLan1.0ChiLan1.0
CELA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21042,839,742 - 42,859,679 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11242,836,504 - 42,856,441 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01237,407,189 - 37,425,684 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11238,291,831 - 38,310,331 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1238,292,562 - 38,310,197 (+)EnsemblpanPan2panpan1.1
CELA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,542,327 - 3,560,777 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,542,309 - 3,560,777 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2742,697,240 - 42,715,697 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0273,587,196 - 3,605,707 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl273,536,169 - 3,605,707 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1273,554,804 - 3,573,236 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0273,541,322 - 3,559,772 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02743,094,493 - 43,113,139 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cela1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494564,244,890 - 64,263,156 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365128,905,339 - 8,919,819 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365128,901,674 - 8,919,819 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CELA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11147,526,354 - 47,545,390 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1147,526,365 - 47,544,726 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037198,550,809 - 198,569,559 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cela1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624816906,121 - 939,696 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624816906,103 - 939,252 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cela1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11262,423,025 - 262,436,240 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Protein Domains
Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000047232 ENTREZGENE
  ENSSSCG00015075833 UniProtKB/Swiss-Prot
  ENSSSCG00045003737 UniProtKB/Swiss-Prot
  ENSSSCG00065043957 UniProtKB/Swiss-Prot
  ENSSSCG00070030376 UniProtKB/Swiss-Prot
  ENSSSCG00085023131 UniProtKB/Swiss-Prot
  ENSSSCG00090018644 UniProtKB/Swiss-Prot
  ENSSSCG00105039582 UniProtKB/Swiss-Prot
  ENSSSCG00110033050 UniProtKB/Swiss-Prot
  ENSSSCG00115015219 UniProtKB/Swiss-Prot
  ENSSSCG00130017212 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000069896 ENTREZGENE
  ENSSSCT00015102157.1 UniProtKB/Swiss-Prot
  ENSSSCT00045006201.1 UniProtKB/Swiss-Prot
  ENSSSCT00065060127.1 UniProtKB/Swiss-Prot
  ENSSSCT00070061127.1 UniProtKB/Swiss-Prot
  ENSSSCT00085044373 UniProtKB/Swiss-Prot
  ENSSSCT00090032858 UniProtKB/Swiss-Prot
  ENSSSCT00105075474 UniProtKB/Swiss-Prot
  ENSSSCT00110063069 UniProtKB/Swiss-Prot
  ENSSSCT00115026478 UniProtKB/Swiss-Prot
  ENSSSCT00130033775 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.10.10 UniProtKB/Swiss-Prot
InterPro Peptidase_S1_Elastase_sf UniProtKB/Swiss-Prot
  Peptidase_S1_PA UniProtKB/Swiss-Prot
  Peptidase_S1_PA_chymotrypsin UniProtKB/Swiss-Prot
  Peptidase_S1A UniProtKB/Swiss-Prot
  Trypsin_dom UniProtKB/Swiss-Prot
  TRYPSIN_HIS UniProtKB/Swiss-Prot
  TRYPSIN_SER UniProtKB/Swiss-Prot
KEGG Report ssc:396766 UniProtKB/Swiss-Prot
NCBI Gene CELA1 ENTREZGENE
PANTHER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER UniProtKB/Swiss-Prot
  CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 1 UniProtKB/Swiss-Prot
Pfam Trypsin UniProtKB/Swiss-Prot
PRINTS CHYMOTRYPSIN UniProtKB/Swiss-Prot
PROSITE TRYPSIN_DOM UniProtKB/Swiss-Prot
  TRYPSIN_HIS UniProtKB/Swiss-Prot
  TRYPSIN_SER UniProtKB/Swiss-Prot
SMART Tryp_SPc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50494 UniProtKB/Swiss-Prot
UniProt A0A480DJK8 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QIP4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0QTI1 ENTREZGENE, UniProtKB/TrEMBL
  CELA1_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q29625 ENTREZGENE
UniProt Secondary Q29625 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-03-19 CELA1  chymotrypsin like elastase 1    chymotrypsin like elastase family member 1  Symbol and/or name change 5135510 APPROVED