MIR127 (microRNA mir-127) - Rat Genome Database

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Gene: MIR127 (microRNA mir-127) Sus scrofa
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Symbol: MIR127
Name: microRNA mir-127
RGD ID: 14104910
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA 127; ssc-mir-127
RGD Orthologs
Human
Mouse
Rat
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7121,709,640 - 121,709,720 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.17121,709,636 - 121,709,715 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27132,099,553 - 132,099,632 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:16381832   PMID:19917043   PMID:21312241   PMID:24499489  


Genomics

Comparative Map Data
MIR127
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7121,709,640 - 121,709,720 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.17121,709,636 - 121,709,715 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27132,099,553 - 132,099,632 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MIR127
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814100,882,979 - 100,883,075 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14100,882,979 - 100,883,075 (+)Ensemblhg38GRCh38
GRCh3714101,349,316 - 101,349,412 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614100,419,068 - 100,419,164 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1481,403,135 - 81,403,231 (+)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1481,531,047 - 81,531,143 (+)NCBIHuRef
CHM1_114101,287,504 - 101,287,600 (+)NCBICHM1_1
T2T-CHM13v2.01495,118,415 - 95,118,511 (+)NCBIT2T-CHM13v2.0
Mir127
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912109,559,280 - 109,559,349 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12109,559,280 - 109,559,349 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3812109,592,846 - 109,592,915 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12109,592,846 - 109,592,915 (+)Ensemblmm10GRCm38
MGSCv3712110,831,056 - 110,831,125 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera12110,787,547 - 110,787,616 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.39NCBI
Mir127
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86134,328,454 - 134,328,550 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6134,328,454 - 134,328,550 (+)EnsemblGRCr8
mRatBN7.26128,546,215 - 128,546,311 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6128,546,215 - 128,546,311 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6128,686,262 - 128,686,358 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06128,982,100 - 128,982,196 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06128,343,690 - 128,343,786 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06133,713,430 - 133,713,526 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6133,713,430 - 133,713,526 (+)Ensemblrn6Rnor6.0
Rnor_5.06142,875,607 - 142,875,703 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera6126,094,654 - 126,094,750 (+)NCBICelera
Cytogenetic Map6q32NCBI
MIR127
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1869,104,938 - 69,104,997 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl869,104,906 - 69,105,016 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha868,622,692 - 68,622,751 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0869,388,428 - 69,388,487 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1869,050,131 - 69,050,190 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0869,116,003 - 69,116,062 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0869,514,181 - 69,514,240 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSSCT00000021061
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl7121,709,640 - 121,709,720 (+)Ensembl
RefSeq Acc Id: NR_038562
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.17121,709,636 - 121,709,715 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000019466 Ensembl, ENTREZGENE
Ensembl Transcript ENSSSCT00000021061 ENTREZGENE
miRBase MI0013144 ENTREZGENE
NCBI Gene MIR127 ENTREZGENE
RNAcentral URS00001E3DAA RNACentral
  URS000075ABC0 RNACentral
  URS0000EF1BE0 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR127  microRNA mir-127    microRNA 127  Symbol and/or name change 5135510 APPROVED