MIR216-1 (microRNA mir-216-1) - Rat Genome Database

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Gene: MIR216-1 (microRNA mir-216-1) Sus scrofa
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Symbol: MIR216-1 (Ensembl: ssc-mir-216-1)
Name: microRNA mir-216-1 (Ensembl:ssc-mir-216-1)
RGD ID: 13971510
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA 216-1; MIR216; ssc-mir-216; ssc-mir-216-1
RGD Orthologs
Human
Mouse
Rat
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl385,334,523 - 85,334,627 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1385,334,523 - 85,334,627 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2390,058,975 - 90,059,079 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
RISC complex  (IEA)

References
Additional References at PubMed
PMID:15885146   PMID:16381832   PMID:19196471   PMID:21312241  


Genomics

Comparative Map Data
MIR216-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl385,334,523 - 85,334,627 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1385,334,523 - 85,334,627 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2390,058,975 - 90,059,079 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MIR216A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38255,988,950 - 55,989,059 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl255,988,950 - 55,989,059 (-)Ensemblhg38GRCh38
GRCh37256,216,085 - 56,216,194 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36256,069,588 - 56,069,697 (-)NCBIBuild 36Build 36hg18NCBI36
Celera256,056,494 - 56,056,603 (-)NCBICelera
Cytogenetic Map2p16.1NCBI
HuRef255,951,101 - 55,951,210 (-)NCBIHuRef
CHM1_1256,146,017 - 56,146,126 (-)NCBICHM1_1
T2T-CHM13v2.0255,985,885 - 55,985,994 (-)NCBIT2T-CHM13v2.0
Mir216a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391128,707,012 - 28,707,083 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1128,707,012 - 28,707,083 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381128,757,012 - 28,757,083 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1128,757,012 - 28,757,083 (+)Ensemblmm10GRCm38
MGSCv371128,657,012 - 28,657,083 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera1131,128,544 - 31,128,615 (+)NCBICelera
Cytogenetic Map11A3.3NCBI
cM Map1116.23NCBI
Mir216a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814106,725,077 - 106,725,182 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl14106,725,077 - 106,725,182 (+)EnsemblGRCr8
mRatBN7.214102,524,105 - 102,524,210 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14102,524,105 - 102,524,210 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx14106,852,319 - 106,852,424 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014108,088,940 - 108,089,045 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014104,561,352 - 104,561,457 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd14107,222,254 - 107,222,359 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive14105,863,267 - 105,863,372 (+)NCBILyon_Normotensive
Lyon_Hypertensive14107,409,381 - 107,409,486 (+)NCBILyon_Hypertensive
F344_StmMcwi14106,224,143 - 106,224,248 (+)NCBIF344_StmMcwi
Rnor_6.014113,112,129 - 113,112,234 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14113,112,129 - 113,112,234 (+)Ensemblrn6Rnor6.0
Rnor_5.014112,802,262 - 112,802,367 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera14101,424,234 - 101,424,339 (+)NCBICelera
Cytogenetic Map14q22NCBI
MIR216A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11056,761,430 - 56,761,534 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1056,761,430 - 56,761,534 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1056,717,816 - 56,717,920 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01057,766,339 - 57,766,443 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1057,766,339 - 57,766,443 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11057,465,981 - 57,466,085 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01057,745,555 - 57,745,659 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01058,037,160 - 58,037,264 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0

Variants

.
Variants in MIR216-1
1 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
nervous system
2 3 3

Sequence


Ensembl Acc Id: ENSSSCT00000025834
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl385,334,523 - 85,334,627 (+)Ensembl
RefSeq Acc Id: NR_038486
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1385,334,523 - 85,334,627 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000024188 Ensembl, ENTREZGENE
Ensembl Transcript ENSSSCT00000025834 ENTREZGENE
miRBase MI0002424 ENTREZGENE
NCBI Gene MIR216-1 ENTREZGENE
RNAcentral URS000075D7E0 RNACentral
  URS00007E375B RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR216-1  microRNA mir-216-1    microRNA 216-1  Symbol and/or name change 5135510 APPROVED