Or12d2c (olfactory receptor family 12 subfamily D member 2C) - Rat Genome Database

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Gene: Or12d2c (olfactory receptor family 12 subfamily D member 2C) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or12d2c
Name: olfactory receptor family 12 subfamily D member 2C
RGD ID: 1333060
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Predicted to be active in membrane. Orthologous to human OR12D1 (olfactory receptor family 12 subfamily D member 1 (gene/pseudogene)) and OR12D2 (olfactory receptor family 12 subfamily D member 2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 13; olfactory receptor 1737; olfactory receptor gene Olr1737; Olr1737; Or13
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,295,863 - 1,296,789 (+)NCBIGRCr8
mRatBN7.2201,290,614 - 1,291,540 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,290,614 - 1,291,540 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,343,830 - 1,344,756 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,347,316 - 1,348,242 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,288,833 - 1,289,759 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,781,320 - 1,782,246 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,781,320 - 1,782,246 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0203,825,496 - 3,826,422 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,381,377 - 1,382,303 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1201,381,376 - 1,382,303 (+)NCBI
Celera202,004,116 - 2,005,042 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. The genomic sequence and comparative analysis of the rat major histocompatibility complex. Hurt P, etal., Genome Res 2004 Apr;14(4):631-9.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:6
Count of miRNA genes:6
Interacting mature miRNAs:6
Transcripts:ENSRNOT00000040388
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126123605Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 5 32 29 27 2 22 2 3 50 40 17 2 10 25

Sequence


Ensembl Acc Id: ENSRNOT00000040388   ⟹   ENSRNOP00000051286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,290,614 - 1,291,540 (+)Ensembl
Rnor_6.0 Ensembl201,781,320 - 1,782,246 (+)Ensembl
RefSeq Acc Id: NM_001001422   ⟹   NP_001001422
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,295,863 - 1,296,789 (+)NCBI
mRatBN7.2201,290,614 - 1,291,540 (+)NCBI
Rnor_6.0201,781,320 - 1,782,246 (+)NCBI
Rnor_5.0203,825,496 - 3,826,422 (+)NCBI
RGSC_v3.4201,381,377 - 1,382,303 (+)RGD
Celera202,004,116 - 2,005,042 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001001422 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAE84081 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000051286.1
RefSeq Acc Id: NP_001001422   ⟸   NM_001001422
- UniProtKB: Q6MFW6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000051286   ⟸   ENSRNOT00000040388
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6MFW6-F1-model_v2 AlphaFold Q6MFW6 1-308 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333060 AgrOrtholog
BioCyc Gene G2FUF-5006 BioCyc
Ensembl Genes ENSRNOG00000048048 Ensembl
  ENSRNOG00000066268 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040388.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_GPCR UniProtKB/TrEMBL
KEGG Report rno:405349 UniProtKB/TrEMBL
NCBI Gene 405349 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or12d2c PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000048048 RatGTEx
  ENSRNOG00000066268 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q6MFW6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or12d2c  olfactory receptor family 12 subfamily D member 2C  Olr1737  olfactory receptor 1737  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1737  olfactory receptor 1737   Olr1737_predicted  olfactory receptor 1737 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1737_predicted  olfactory receptor 1737 (predicted)      Symbol and Name status set to approved 70820 APPROVED