Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nudt12 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NUDT12 mRNA] | CTD | PMID:31150632 | Nudt12 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | NUDT12 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of NUDT12 mRNA | CTD | PMID:22079256 | Nudt12 | Rat | 1,1-dichloroethene | decreases expression | ISO | Nudt12 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of NUDT12 mRNA | CTD | PMID:26682919 | Nudt12 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Nudt12 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of NUDT12 mRNA | CTD | PMID:22206623 | Nudt12 | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of NUDT12 mRNA | CTD | PMID:32145629 | Nudt12 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Nudt12 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | Nudt12 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Nudt12 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NUDT12 mRNA | CTD | PMID:21570461 | Nudt12 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of NUDT12 mRNA | CTD | PMID:30851411 | Nudt12 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Nudt12 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of NUDT12 mRNA | CTD | PMID:26251327 | Nudt12 | Rat | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin results in decreased expression of NUDT12 protein | CTD | PMID:34915118 | Nudt12 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Nudt12 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of NUDT12 mRNA | CTD | PMID:18648102 | Nudt12 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of NUDT12 mRNA | CTD | PMID:30047161 | Nudt12 | Rat | aflatoxin B1 | decreases methylation | ISO | NUDT12 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of NUDT12 gene | CTD | PMID:27153756 | Nudt12 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of NUDT12 mRNA | CTD | PMID:30047161 | Nudt12 | Rat | aristolochic acid A | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of NUDT12 mRNA | CTD | PMID:33212167 | Nudt12 | Rat | arsenous acid | multiple interactions | ISO | NUDT12 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NUDT12 protein] | CTD | PMID:26598702 | Nudt12 | Rat | belinostat | increases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | belinostat results in increased expression of NUDT12 mRNA | CTD | PMID:27188386 | Nudt12 | Rat | benzo[a]pyrene | increases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of NUDT12 mRNA | CTD | PMID:20106945 | Nudt12 | Rat | benzo[a]pyrene | decreases methylation | ISO | NUDT12 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of NUDT12 5' UTR and Benzo(a)pyrene results in decreased methylation of NUDT12 promoter | CTD | PMID:27901495 | Nudt12 | Rat | benzo[a]pyrene | decreases expression | ISO | Nudt12 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of NUDT12 mRNA | CTD | PMID:22228805 | Nudt12 | Rat | benzo[a]pyrene | increases expression | ISO | Nudt12 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of NUDT12 mRNA | CTD | PMID:19770486 | Nudt12 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NUDT12 mRNA | CTD | PMID:25181051 more ... | Nudt12 | Rat | butanal | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of NUDT12 mRNA | CTD | PMID:26079696 | Nudt12 | Rat | chlorpyrifos | decreases expression | ISO | Nudt12 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of NUDT12 mRNA | CTD | PMID:37019170 | Nudt12 | Rat | cisplatin | multiple interactions | ISO | NUDT12 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of NUDT12 mRNA | CTD | PMID:27392435 | Nudt12 | Rat | clotrimazole | decreases expression | EXP | | 6480464 | Clotrimazole results in decreased expression of NUDT12 mRNA | CTD | PMID:30047161 | Nudt12 | Rat | copper(II) sulfate | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of NUDT12 mRNA | CTD | PMID:19549813 | Nudt12 | Rat | cyclosporin A | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of NUDT12 mRNA | CTD | PMID:20106945 | Nudt12 | Rat | diarsenic trioxide | multiple interactions | ISO | NUDT12 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NUDT12 protein] | CTD | PMID:26598702 | Nudt12 | Rat | dibenzofurans | increases expression | ISO | Nudt12 (Mus musculus) | 6480464 | Dibenzofurans results in increased expression of NUDT12 mRNA | CTD | PMID:34254344 | Nudt12 | Rat | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of NUDT12 mRNA | CTD | PMID:33729688 | Nudt12 | Rat | dorsomorphin | multiple interactions | ISO | NUDT12 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NUDT12 mRNA | CTD | PMID:27188386 | Nudt12 | Rat | epoxiconazole | decreases expression | ISO | Nudt12 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of NUDT12 mRNA | CTD | PMID:35436446 | Nudt12 | Rat | ethanol | affects expression | ISO | Nudt12 (Mus musculus) | 6480464 | Ethanol affects the expression of NUDT12 mRNA | CTD | PMID:30319688 | Nudt12 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of NUDT12 mRNA | CTD | PMID:33387578 | Nudt12 | Rat | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of NUDT12 mRNA | CTD | PMID:24136188 | Nudt12 | Rat | gold atom | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Gold results in decreased expression of NUDT12 mRNA | CTD | PMID:25523186 | Nudt12 | Rat | gold(0) | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Gold results in decreased expression of NUDT12 mRNA | CTD | PMID:25523186 | Nudt12 | Rat | hydrogen peroxide | affects expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of NUDT12 mRNA | CTD | PMID:20044591 | Nudt12 | Rat | hydroxyurea | increases expression | ISO | Nudt12 (Mus musculus) | 6480464 | Hydroxyurea results in increased expression of NUDT12 mRNA | CTD | PMID:12929121 | Nudt12 | Rat | indometacin | decreases expression | EXP | | 6480464 | Indomethacin results in decreased expression of NUDT12 mRNA | CTD | PMID:36868495 | Nudt12 | Rat | Licochalcone B | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | licochalcone B results in decreased expression of NUDT12 mRNA | CTD | PMID:33647349 | Nudt12 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of NUDT12 mRNA | CTD | PMID:30467583 | Nudt12 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of NUDT12 mRNA | CTD | PMID:30047161 | Nudt12 | Rat | methylisothiazolinone | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in decreased expression of NUDT12 mRNA | CTD | PMID:31629900 | Nudt12 | Rat | methylmercury chloride | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of NUDT12 mRNA | CTD | PMID:28001369 | Nudt12 | Rat | ozone | multiple interactions | ISO | NUDT12 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the methylation of NUDT12 gene | CTD | PMID:35835166 | Nudt12 | Rat | p-anisidine | increases expression | ISO | Nudt12 (Mus musculus) | 6480464 | 4-anisidine results in increased expression of NUDT12 mRNA | CTD | PMID:12929121 | Nudt12 | Rat | paclitaxel | increases expression | ISO | Nudt12 (Mus musculus) | 6480464 | Paclitaxel results in increased expression of NUDT12 mRNA | CTD | PMID:12929121 | Nudt12 | Rat | paracetamol | affects expression | ISO | Nudt12 (Mus musculus) | 6480464 | Acetaminophen affects the expression of NUDT12 mRNA | CTD | PMID:17562736 | Nudt12 | Rat | paracetamol | increases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of NUDT12 mRNA | CTD | PMID:26690555 | Nudt12 | Rat | paracetamol | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of NUDT12 mRNA | CTD | PMID:21420995 and PMID:29067470 | Nudt12 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of NUDT12 mRNA | CTD | PMID:27153767 | Nudt12 | Rat | phenobarbital | affects expression | ISO | Nudt12 (Mus musculus) | 6480464 | Phenobarbital affects the expression of NUDT12 mRNA | CTD | PMID:19136022 | Nudt12 | Rat | pirinixic acid | affects expression | ISO | Nudt12 (Mus musculus) | 6480464 | pirinixic acid affects the expression of NUDT12 mRNA | CTD | PMID:19136022 | Nudt12 | Rat | pirinixic acid | increases expression | ISO | Nudt12 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of NUDT12 mRNA | CTD | PMID:17950772 more ... | Nudt12 | Rat | pirinixic acid | multiple interactions | ISO | Nudt12 (Mus musculus) | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in increased expression of NUDT12 mRNA] | CTD | PMID:17950772 | Nudt12 | Rat | potassium chromate | multiple interactions | ISO | NUDT12 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of NUDT12 mRNA | CTD | PMID:22079256 | Nudt12 | Rat | potassium chromate | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of NUDT12 mRNA | CTD | PMID:22079256 | Nudt12 | Rat | rac-lactic acid | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of NUDT12 mRNA | CTD | PMID:30851411 | Nudt12 | Rat | resveratrol | decreases expression | EXP | | 6480464 | resveratrol results in decreased expression of NUDT12 mRNA | CTD | PMID:25905778 | Nudt12 | Rat | SB 431542 | multiple interactions | ISO | NUDT12 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NUDT12 mRNA | CTD | PMID:27188386 | Nudt12 | Rat | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide results in decreased expression of NUDT12 mRNA | CTD | PMID:32721576 | Nudt12 | Rat | sodium arsenite | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of NUDT12 mRNA | CTD | PMID:38568856 | Nudt12 | Rat | sunitinib | increases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of NUDT12 mRNA | CTD | PMID:31533062 | Nudt12 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of NUDT12 mRNA | CTD | PMID:31150632 | Nudt12 | Rat | tetrachloromethane | decreases expression | ISO | Nudt12 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of NUDT12 mRNA | CTD | PMID:31919559 | Nudt12 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NUDT12 mRNA] | CTD | PMID:31150632 | Nudt12 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of NUDT12 mRNA | CTD | PMID:34492290 | Nudt12 | Rat | thiram | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Thiram results in decreased expression of NUDT12 mRNA | CTD | PMID:38568856 | Nudt12 | Rat | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of NUDT12 gene | CTD | PMID:27618143 | Nudt12 | Rat | trichostatin A | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of NUDT12 mRNA | CTD | PMID:26272509 | Nudt12 | Rat | trichostatin A | multiple interactions | ISO | NUDT12 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NUDT12 mRNA | CTD | PMID:27188386 | Nudt12 | Rat | triphenyl phosphate | affects expression | ISO | NUDT12 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of NUDT12 mRNA | CTD | PMID:37042841 | Nudt12 | Rat | valproic acid | decreases expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of NUDT12 mRNA | CTD | PMID:23179753 | Nudt12 | Rat | valproic acid | affects expression | ISO | NUDT12 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NUDT12 mRNA | CTD | PMID:25979313 | |