Tbx20 (T-box transcription factor 20) - Rat Genome Database

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Gene: Tbx20 (T-box transcription factor 20) Rattus norvegicus
Analyze
Symbol: Tbx20
Name: T-box transcription factor 20
RGD ID: 1309396
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in positive regulation of apoptotic process and positive regulation of cell cycle process. Predicted to be located in chromatin and cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in atrial heart septal defect; atrial heart septal defect 4; congenital heart disease; tetralogy of Fallot; and ventricular septal defect. Orthologous to human TBX20 (T-box transcription factor 20); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC315497; T-box 20; T-box transcription factor TBX20
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8831,475,963 - 31,534,051 (-)NCBIGRCr8
mRatBN7.2823,200,104 - 23,258,218 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl823,204,507 - 23,258,175 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx827,227,979 - 27,286,461 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0825,525,230 - 25,583,718 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0823,424,750 - 23,483,234 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0825,849,394 - 25,904,570 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl825,850,962 - 25,904,570 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0825,880,011 - 25,934,699 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4824,366,065 - 24,407,270 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1824,366,082 - 24,407,264 (-)NCBI
Celera824,791,728 - 24,832,252 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aortic valve development  (ISO)
aortic valve morphogenesis  (ISO)
atrial septum morphogenesis  (ISO)
atrioventricular canal development  (ISO)
atrioventricular valve development  (ISO)
blood circulation  (ISO)
branching involved in blood vessel morphogenesis  (ISO)
cardiac chamber formation  (ISO)
cardiac muscle tissue morphogenesis  (ISO)
cardiac right ventricle morphogenesis  (ISO)
cardiac septum development  (ISO)
cell fate specification  (IBA)
cell population proliferation  (ISO)
dorsal/ventral pattern formation  (ISO)
embryonic heart tube development  (ISO)
embryonic heart tube elongation  (ISO)
embryonic heart tube morphogenesis  (ISO)
endocardial cushion formation  (ISO)
endocardial cushion morphogenesis  (ISO)
foramen ovale closure  (ISO)
heart looping  (IBA,ISO)
mesenchymal cell development  (ISO)
motor neuron migration  (ISO)
muscle contraction  (ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of SMAD protein signal transduction  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
outflow tract morphogenesis  (ISO)
outflow tract septum morphogenesis  (ISO)
pericardium morphogenesis  (ISO)
positive regulation of apoptotic process  (IMP)
positive regulation of BMP signaling pathway  (ISO)
positive regulation of cardiac muscle cell proliferation  (ISO)
positive regulation of cell cycle process  (IMP)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of epithelial to mesenchymal transition  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
pulmonary valve formation  (ISO)
pulmonary vein morphogenesis  (ISO)
regulation of transcription by RNA polymerase II  (IBA)
tricuspid valve development  (ISO)
vasculogenesis  (IBA)
visceral motor neuron differentiation  (ISO)

Cellular Component
chromatin  (IBA)
cytoplasm  (ISO)
nucleus  (IBA,ISO)

References

References - curated
# Reference Title Reference Citation
1. T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Cai CL, etal., Development. 2005 May;132(10):2475-87. Epub 2005 Apr 20.
2. Association of TBX20 gene polymorphism with congenital heart disease in Han Chinese neonates. Chen J, etal., Pediatr Cardiol. 2015 Apr;36(4):737-42. doi: 10.1007/s00246-014-1073-5. Epub 2014 Dec 9.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. DNA methylation status of TBX20 in patients with tetralogy of Fallot. Gong J, etal., BMC Med Genomics. 2019 May 28;12(1):75. doi: 10.1186/s12920-019-0534-3.
5. Characterization of TBX20 in human hearts and its regulation by TFAP2. Hammer S, etal., J Cell Biochem. 2008 Jun 1;104(3):1022-33. doi: 10.1002/jcb.21686.
6. Silencing of TBX20 gene expression in rat myocardial and human embryonic kidney cells leads to cell cycle arrest in G2 phase. Liu P, etal., Mol Med Rep. 2016 Oct;14(4):2904-14. doi: 10.3892/mmr.2016.5660. Epub 2016 Aug 19.
7. [Association between Tbx20 gene polymorphism and congenital atrial septal defects]. Ma Y, etal., Zhonghua Nei Ke Za Zhi. 2015 Oct;54(10):860-4.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Differential expression and function of Tbx5 and Tbx20 in cardiac development. Plageman TF Jr and Yutzey KE, J Biol Chem. 2004 Apr 30;279(18):19026-34. Epub 2004 Feb 20.
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive gene review and curation RGD comprehensive gene curation
15. Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development. Takeuchi JK, etal., Development. 2005 May;132(10):2463-74. Epub 2005 Apr 20.
16. Association between the promoter methylation of the TBX20 gene and tetralogy of fallot. Yang X, etal., Scand Cardiovasc J. 2018 Oct;52(5):287-291. doi: 10.1080/14017431.2018.1499955. Epub 2018 Aug 7.
17. Mild decrease in TBX20 promoter activity is a potentially protective factor against congenital heart defects in the Han Chinese population. Yu LW, etal., Sci Rep. 2016 Apr 1;6:23662. doi: 10.1038/srep23662.
Additional References at PubMed
PMID:14550786   PMID:15843414   PMID:15901664   PMID:17119020   PMID:17668378   PMID:18834961   PMID:19661464   PMID:19762328   PMID:22164283   PMID:26895318  


Genomics

Comparative Map Data
Tbx20
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8831,475,963 - 31,534,051 (-)NCBIGRCr8
mRatBN7.2823,200,104 - 23,258,218 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl823,204,507 - 23,258,175 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx827,227,979 - 27,286,461 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0825,525,230 - 25,583,718 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0823,424,750 - 23,483,234 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0825,849,394 - 25,904,570 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl825,850,962 - 25,904,570 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0825,880,011 - 25,934,699 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4824,366,065 - 24,407,270 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1824,366,082 - 24,407,264 (-)NCBI
Celera824,791,728 - 24,832,252 (-)NCBICelera
Cytogenetic Map8q13NCBI
TBX20
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38735,202,430 - 35,254,100 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl735,202,430 - 35,254,100 (-)EnsemblGRCh38hg38GRCh38
GRCh37735,242,042 - 35,293,711 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36735,208,567 - 35,259,767 (-)NCBINCBI36Build 36hg18NCBI36
Build 34735,044,351 - 35,066,482NCBI
Celera735,226,693 - 35,278,408 (-)NCBICelera
Cytogenetic Map7p14.2NCBI
HuRef735,123,200 - 35,174,873 (-)NCBIHuRef
CHM1_1735,241,632 - 35,293,323 (-)NCBICHM1_1
T2T-CHM13v2.0735,343,508 - 35,395,177 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2735,281,142 - 35,332,810 (-)NCBI
Tbx20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39924,632,108 - 24,685,580 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl924,629,434 - 24,685,599 (-)EnsemblGRCm39 Ensembl
GRCm38924,720,812 - 24,774,303 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl924,718,138 - 24,774,303 (-)EnsemblGRCm38mm10GRCm38
MGSCv37924,527,648 - 24,578,746 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36924,473,611 - 24,524,709 (-)NCBIMGSCv36mm8
Celera921,982,053 - 22,032,919 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map910.25NCBI
Tbx20
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554607,794,313 - 7,856,906 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554607,794,313 - 7,856,906 (+)NCBIChiLan1.0ChiLan1.0
TBX20
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2640,023,457 - 40,077,197 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1788,350,337 - 88,401,932 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0735,855,969 - 35,878,533 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1736,089,552 - 36,114,447 (-)NCBIpanpan1.1PanPan1.1panPan2
TBX20
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11446,891,706 - 46,946,899 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1446,896,228 - 46,947,507 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1446,333,468 - 46,388,693 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01446,832,241 - 46,887,482 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1446,835,802 - 46,887,894 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11446,939,599 - 46,994,783 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01446,616,244 - 46,671,623 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01446,994,716 - 47,045,430 (-)NCBIUU_Cfam_GSD_1.0
Tbx20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511891,680,618 - 91,727,770 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647810,888,045 - 10,939,564 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647810,887,900 - 10,939,510 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBX20
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1838,635,617 - 38,678,133 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11838,635,603 - 38,681,690 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21842,467,087 - 42,508,195 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TBX20
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12123,166,020 - 23,222,416 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2123,166,109 - 23,224,657 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604281,702,390 - 81,757,198 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbx20
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474025,645,895 - 25,697,132 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474025,645,526 - 25,698,235 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tbx20
542 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:257
Count of miRNA genes:169
Interacting mature miRNAs:188
Transcripts:ENSRNOT00000064783
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8124597739Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
2317882Alcrsp24Alcohol response QTL 243.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)8125902202Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat

Markers in Region
D8Got28  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2823,239,150 - 23,239,399 (+)MAPPERmRatBN7.2
Rnor_6.0825,885,619 - 25,885,867NCBIRnor6.0
Rnor_5.0825,915,730 - 25,915,978UniSTSRnor5.0
RGSC_v3.4824,387,236 - 24,387,485RGDRGSC3.4
RGSC_v3.4824,387,237 - 24,387,485UniSTSRGSC3.4
RGSC_v3.1824,387,237 - 24,387,485RGD
Celera824,812,889 - 24,813,153UniSTS
RH 3.4 Map8212.69UniSTS
RH 3.4 Map8212.69RGD
Cytogenetic Map8q13UniSTS
TBX20  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2823,254,466 - 23,254,682 (+)MAPPERmRatBN7.2
Rnor_6.0825,900,863 - 25,901,078NCBIRnor6.0
Rnor_5.0825,930,974 - 25,931,189UniSTSRnor5.0
Celera824,828,545 - 24,828,760UniSTS
Cytogenetic Map8q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 3 49 74 91 89 59 18 59 6 168 87 54 13 41 30

Sequence


Ensembl Acc Id: ENSRNOT00000064783   ⟹   ENSRNOP00000063295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl823,217,989 - 23,258,175 (-)Ensembl
Rnor_6.0 Ensembl825,864,456 - 25,904,570 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082744   ⟹   ENSRNOP00000075397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl823,204,507 - 23,258,175 (-)Ensembl
Rnor_6.0 Ensembl825,850,962 - 25,904,564 (-)Ensembl
RefSeq Acc Id: NM_001108132   ⟹   NP_001101602
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8831,493,819 - 31,534,009 (-)NCBI
mRatBN7.2823,217,961 - 23,258,151 (-)NCBI
Rnor_6.0825,864,448 - 25,904,570 (-)NCBI
Rnor_5.0825,880,011 - 25,934,699 (-)NCBI
RGSC_v3.4824,366,065 - 24,407,270 (-)RGD
Celera824,791,728 - 24,832,252 (-)RGD
Sequence:
RefSeq Acc Id: NM_001401090   ⟹   NP_001388019
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8831,475,963 - 31,534,009 (-)NCBI
mRatBN7.2823,200,104 - 23,258,151 (-)NCBI
RefSeq Acc Id: XM_039081364   ⟹   XP_038937292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8831,475,963 - 31,534,051 (-)NCBI
mRatBN7.2823,200,104 - 23,258,218 (-)NCBI
RefSeq Acc Id: XM_063265373   ⟹   XP_063121443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8831,475,963 - 31,529,729 (-)NCBI
RefSeq Acc Id: NP_001101602   ⟸   NM_001108132
- Peptide Label: isoform 2
- UniProtKB: D3ZUF4 (UniProtKB/TrEMBL),   A6JYB1 (UniProtKB/TrEMBL),   A6JYB2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075397   ⟸   ENSRNOT00000082744
Ensembl Acc Id: ENSRNOP00000063295   ⟸   ENSRNOT00000064783
RefSeq Acc Id: XP_038937292   ⟸   XM_039081364
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001388019   ⟸   NM_001401090
- Peptide Label: isoform 1
- UniProtKB: A0A0G2KAH3 (UniProtKB/TrEMBL),   A6JYB0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121443   ⟸   XM_063265373
- Peptide Label: isoform X2
Protein Domains
T-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2KAH3-F1-model_v2 AlphaFold A0A0G2KAH3 1-446 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695813
Promoter ID:EPDNEW_R6337
Type:single initiation site
Name:Tbx20_1
Description:T-box 20
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0825,904,546 - 25,904,606EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309396 AgrOrtholog
BioCyc Gene G2FUF-31345 BioCyc
Ensembl Genes ENSRNOG00000016181 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064783.3 UniProtKB/TrEMBL
  ENSRNOT00000082744.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.820 UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/TrEMBL
  T-box_DNA-bd UniProtKB/TrEMBL
  T-box_sf UniProtKB/TrEMBL
  TF_T-box UniProtKB/TrEMBL
  TF_T-box_CS UniProtKB/TrEMBL
KEGG Report rno:315497 UniProtKB/TrEMBL
NCBI Gene 315497 ENTREZGENE
PANTHER T-BOX TRANSCRIPTION FACTOR TBX20 UniProtKB/TrEMBL
  TF_T-box UniProtKB/TrEMBL
Pfam T-box UniProtKB/TrEMBL
PhenoGen Tbx20 PhenoGen
PRINTS TBOX UniProtKB/TrEMBL
PROSITE TBOX_1 UniProtKB/TrEMBL
  TBOX_2 UniProtKB/TrEMBL
  TBOX_3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016181 RatGTEx
SMART TBOX UniProtKB/TrEMBL
Superfamily-SCOP P53_like_DNA_bnd UniProtKB/TrEMBL
UniProt A0A0G2KAH3 ENTREZGENE, UniProtKB/TrEMBL
  A6JYB0 ENTREZGENE, UniProtKB/TrEMBL
  A6JYB1 ENTREZGENE, UniProtKB/TrEMBL
  A6JYB2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZUF4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-05 Tbx20  T-box transcription factor 20  Tbx20  T-box 20  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Tbx20  T-box 20   Tbx20_predicted  T-box 20 (predicted)  'predicted' is removed 2292626 APPROVED