Larp6 (La ribonucleoprotein 6, translational regulator) - Rat Genome Database

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Gene: Larp6 (La ribonucleoprotein 6, translational regulator) Rattus norvegicus
Analyze
Symbol: Larp6
Name: La ribonucleoprotein 6, translational regulator
RGD ID: 1308414
Description: Predicted to enable RNA binding activity and myosin binding activity. Predicted to be involved in positive regulation of collagen biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleus. Orthologous to human LARP6 (La ribonucleoprotein 6, translational regulator); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: death-associated LA motif protein; La ribonucleoprotein domain family, member 6; la-related protein 6; LOC315731; RGD1308414; similar to acheron
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8870,079,753 - 70,101,175 (+)NCBIGRCr8
mRatBN7.2861,183,744 - 61,205,548 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl861,184,116 - 61,205,535 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx866,692,453 - 66,713,653 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0864,965,027 - 64,986,227 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0862,834,883 - 62,856,084 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0865,611,570 - 65,632,706 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl865,611,570 - 65,632,706 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0865,362,299 - 65,382,759 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4864,655,008 - 64,676,258 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1864,674,131 - 64,694,704 (+)NCBI
Celera860,610,882 - 60,632,170 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-methylcholine  (ISO)
3,7-dihydropurine-6-thione  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
CGP 52608  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
dicrotophos  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
lead(0)  (ISO)
menadione  (ISO)
mercaptopurine  (EXP)
methylparaben  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
purine-6-thiol  (EXP)
quercetin  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
thapsigargin  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
trichloroethene  (EXP)
troglitazone  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:20603131   PMID:21746880   PMID:22190748  


Genomics

Comparative Map Data
Larp6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8870,079,753 - 70,101,175 (+)NCBIGRCr8
mRatBN7.2861,183,744 - 61,205,548 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl861,184,116 - 61,205,535 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx866,692,453 - 66,713,653 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0864,965,027 - 64,986,227 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0862,834,883 - 62,856,084 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0865,611,570 - 65,632,706 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl865,611,570 - 65,632,706 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0865,362,299 - 65,382,759 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4864,655,008 - 64,676,258 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1864,674,131 - 64,694,704 (+)NCBI
Celera860,610,882 - 60,632,170 (+)NCBICelera
Cytogenetic Map8q24NCBI
LARP6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381570,829,130 - 70,854,157 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1570,829,130 - 70,854,157 (-)EnsemblGRCh38hg38GRCh38
GRCh371571,121,469 - 71,146,496 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361568,910,943 - 68,933,552 (-)NCBINCBI36Build 36hg18NCBI36
Celera1548,014,786 - 48,037,397 (-)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1547,959,434 - 47,982,049 (-)NCBIHuRef
CHM1_11571,242,143 - 71,264,762 (-)NCBICHM1_1
T2T-CHM13v2.01568,652,085 - 68,677,121 (-)NCBIT2T-CHM13v2.0
Larp6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39960,620,404 - 60,646,084 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl960,620,272 - 60,646,084 (+)EnsemblGRCm39 Ensembl
GRCm38960,713,121 - 60,738,801 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl960,712,989 - 60,738,801 (+)EnsemblGRCm38mm10GRCm38
MGSCv37960,560,928 - 60,586,608 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36960,511,127 - 60,536,807 (+)NCBIMGSCv36mm8
Celera957,938,375 - 57,963,474 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map932.87NCBI
Larp6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554506,050,057 - 6,073,379 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554506,050,260 - 6,073,388 (+)NCBIChiLan1.0ChiLan1.0
LARP6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21660,095,231 - 60,117,915 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11564,259,145 - 64,281,825 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01549,781,184 - 49,803,856 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11568,547,930 - 68,552,899 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1568,547,937 - 68,552,899 (-)Ensemblpanpan1.1panPan2
LARP6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13034,521,695 - 34,535,629 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3034,521,699 - 34,528,027 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3034,455,443 - 34,476,857 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03034,723,013 - 34,744,437 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3034,723,035 - 34,744,422 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13034,668,132 - 34,689,525 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03034,707,475 - 34,728,899 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03034,959,391 - 34,980,801 (-)NCBIUU_Cfam_GSD_1.0
Larp6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640112,521,849 - 112,539,209 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647130,370,440 - 30,385,518 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647130,369,912 - 30,387,272 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LARP6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1168,507,976 - 168,530,239 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11168,508,472 - 168,530,439 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21186,790,170 - 186,814,740 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LARP6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12612,605,050 - 12,626,661 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2612,605,147 - 12,628,761 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048128,862,421 - 128,884,186 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Larp6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247813,014,747 - 3,042,498 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247813,014,655 - 3,050,922 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Larp6
227 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:69
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000017147
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84071306682925667Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)84186687675097878Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)85423764485365202Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
631216Stl9Serum triglyceride level QTL 94.710.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)84186701070386132Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85009524982460899Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)85423764485365202Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85009524982460899Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat

Markers in Region
RH139352  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2861,205,032 - 61,205,256 (+)MAPPERmRatBN7.2
Rnor_6.0865,632,204 - 65,632,427NCBIRnor6.0
Rnor_5.0865,382,257 - 65,382,480UniSTSRnor5.0
RGSC_v3.4864,675,756 - 64,675,979UniSTSRGSC3.4
Celera860,631,668 - 60,631,891UniSTS
RH 3.4 Map8710.0UniSTS
Cytogenetic Map8q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 73 72 41 25 41 6 200 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000017147   ⟹   ENSRNOP00000017147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl861,184,116 - 61,205,535 (+)Ensembl
Rnor_6.0 Ensembl865,611,570 - 65,632,706 (+)Ensembl
RefSeq Acc Id: NM_001108154   ⟹   NP_001101624
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,079,753 - 70,101,175 (+)NCBI
mRatBN7.2861,184,116 - 61,205,535 (+)NCBI
Rnor_6.0865,611,570 - 65,632,706 (+)NCBI
Rnor_5.0865,362,299 - 65,382,759 (+)NCBI
RGSC_v3.4864,655,008 - 64,676,258 (+)RGD
Celera860,610,882 - 60,632,170 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001101624 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL95722 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017147.5
RefSeq Acc Id: NP_001101624   ⟸   NM_001108154
- UniProtKB: D3ZCR5 (UniProtKB/TrEMBL),   A6J549 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017147   ⟸   ENSRNOT00000017147
Protein Domains
HTH La-type RNA-binding   SUZ-C

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZCR5-F1-model_v2 AlphaFold D3ZCR5 1-492 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696045
Promoter ID:EPDNEW_R6570
Type:initiation region
Name:Larp6_1
Description:La ribonucleoprotein domain family, member 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0865,611,602 - 65,611,662EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308414 AgrOrtholog
BioCyc Gene G2FUF-30210 BioCyc
Ensembl Genes ENSRNOG00000012438 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017147.7 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
InterPro La_dom_prot UniProtKB/TrEMBL
  LARP6_RRM UniProtKB/TrEMBL
  Lupus_La UniProtKB/TrEMBL
  Lupus_La_RNA-bd UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  SUZ-C UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:315731 UniProtKB/TrEMBL
NCBI Gene 315731 ENTREZGENE
PANTHER PTHR22792 UniProtKB/TrEMBL
  PTHR22792:SF71 UniProtKB/TrEMBL
Pfam PF05383 UniProtKB/TrEMBL
PhenoGen Larp6 PhenoGen
PRINTS LUPUSLA UniProtKB/TrEMBL
PROSITE HTH_LA UniProtKB/TrEMBL
  SUZ_C UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012438 RatGTEx
SMART SM00715 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A6J549 ENTREZGENE, UniProtKB/TrEMBL
  D3ZCR5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-13 Larp6  La ribonucleoprotein 6, translational regulator  Larp6  La ribonucleoprotein domain family, member 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Larp6  La ribonucleoprotein domain family, member 6   Larp6_predicted  La ribonucleoprotein domain family, member 6 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Larp6_predicted  La ribonucleoprotein domain family, member 6 (predicted)  RGD1308414_predicted  similar to acheron; death-associated LA motif protein (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1308414_predicted  similar to acheron; death-associated LA motif protein (predicted)  LOC315731_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC315731_predicted  similar to acheron; death-associated LA motif protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL