Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Chst1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Chst1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CHST1 mRNA | CTD | PMID:22206623 | Chst1 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Chst1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of CHST1 mRNA | CTD | PMID:17942748 | Chst1 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Chst1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CHST1 mRNA | CTD | PMID:17942748 | Chst1 | Rat | 17beta-estradiol | decreases expression | ISO | Chst1 (Mus musculus) | 6480464 | Estradiol results in decreased expression of CHST1 mRNA | CTD | PMID:19484750 | Chst1 | Rat | 17beta-estradiol | multiple interactions | ISO | CHST1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of CHST1 mRNA | CTD | PMID:30165855 | Chst1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Chst1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CHST1 mRNA | CTD | PMID:17942748 | Chst1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CHST1 mRNA | CTD | PMID:32109520 and PMID:34747641 | Chst1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Chst1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CHST1 mRNA | CTD | PMID:19933214 | Chst1 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | Chst1 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Chst1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:38648751 | Chst1 | Rat | 3,3',4,4',5-pentachlorobiphenyl | multiple interactions | EXP | | 6480464 | AHR gene mutant form inhibits the reaction [3 more ... | CTD | PMID:34256052 | Chst1 | Rat | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:34256052 | Chst1 | Rat | 3,3',5-triiodo-L-thyronine | increases expression | ISO | Chst1 (Mus musculus) | 6480464 | Triiodothyronine results in increased expression of CHST1 mRNA | CTD | PMID:25172293 | Chst1 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CHST1 mRNA | CTD | PMID:36041667 | Chst1 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Chst1 (Mus musculus) | 6480464 | bisphenol S affects the methylation of CHST1 gene | CTD | PMID:31683443 | Chst1 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Chst1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of CHST1 mRNA | CTD | PMID:28973697 | Chst1 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of CHST1 mRNA | CTD | PMID:30047161 | Chst1 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of CHST1 mRNA | CTD | PMID:35163327 | Chst1 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of CHST1 mRNA | CTD | PMID:30047161 | Chst1 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of CHST1 mRNA | CTD | PMID:30779732 | Chst1 | Rat | arsenous acid | decreases expression | ISO | CHST1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of CHST1 mRNA | CTD | PMID:26705709 | Chst1 | Rat | atrazine | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | Atrazine results in increased expression of CHST1 mRNA | CTD | PMID:22378314 | Chst1 | Rat | benzo[a]pyrene | decreases expression | ISO | Chst1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of CHST1 mRNA | CTD | PMID:21569818 | Chst1 | Rat | benzo[a]pyrene | affects methylation | ISO | CHST1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of CHST1 5' UTR and Benzo(a)pyrene affects the methylation of CHST1 promoter | CTD | PMID:27901495 | Chst1 | Rat | benzo[a]pyrene | multiple interactions | ISO | Chst1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CHST1 mRNA | CTD | PMID:27858113 | Chst1 | Rat | benzo[b]fluoranthene | decreases expression | ISO | Chst1 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in decreased expression of CHST1 mRNA | CTD | PMID:26377693 | Chst1 | Rat | benzo[b]fluoranthene | multiple interactions | ISO | Chst1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CHST1 mRNA | CTD | PMID:27858113 | Chst1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CHST1 mRNA | CTD | PMID:25181051 and PMID:34947998 | Chst1 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CHST1 mRNA | CTD | PMID:36041667 | Chst1 | Rat | bisphenol A | decreases methylation | ISO | CHST1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of CHST1 gene | CTD | PMID:31601247 | Chst1 | Rat | bisphenol A | increases expression | ISO | Chst1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of CHST1 mRNA | CTD | PMID:38701888 | Chst1 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of CHST1 gene | CTD | PMID:28505145 | Chst1 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CHST1 mRNA | CTD | PMID:36041667 | Chst1 | Rat | buta-1,3-diene | decreases expression | ISO | Chst1 (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of CHST1 mRNA | CTD | PMID:29038090 | Chst1 | Rat | butanal | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of CHST1 mRNA | CTD | PMID:26079696 | Chst1 | Rat | Butylparaben | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | butylparaben results in increased expression of CHST1 mRNA | CTD | PMID:17121429 | Chst1 | Rat | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of CHST1 mRNA | CTD | PMID:19167457 | Chst1 | Rat | carbon nanotube | decreases expression | ISO | Chst1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Chst1 | Rat | chlorpyrifos | increases expression | ISO | Chst1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of CHST1 mRNA | CTD | PMID:37019170 | Chst1 | Rat | chrysene | multiple interactions | ISO | Chst1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CHST1 mRNA | CTD | PMID:27858113 | Chst1 | Rat | cisplatin | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of CHST1 mRNA | CTD | PMID:27392435 | Chst1 | Rat | cisplatin | multiple interactions | ISO | CHST1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of CHST1 mRNA | CTD | PMID:27392435 | Chst1 | Rat | clotrimazole | increases expression | EXP | | 6480464 | Clotrimazole results in increased expression of CHST1 mRNA | CTD | PMID:30047161 | Chst1 | Rat | cyclosporin A | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of CHST1 mRNA | CTD | PMID:20106945 and PMID:27989131 | Chst1 | Rat | diarsenic trioxide | decreases expression | ISO | CHST1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of CHST1 mRNA | CTD | PMID:26705709 | Chst1 | Rat | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of CHST1 mRNA | CTD | PMID:33729688 | Chst1 | Rat | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of CHST1 mRNA | CTD | PMID:25182419 | Chst1 | Rat | ethanol | affects splicing | ISO | Chst1 (Mus musculus) | 6480464 | Ethanol affects the splicing of CHST1 mRNA | CTD | PMID:30319688 | Chst1 | Rat | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of CHST1 mRNA | CTD | PMID:34044035 | Chst1 | Rat | folic acid | multiple interactions | ISO | Chst1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of CHST1 mRNA | CTD | PMID:22206623 | Chst1 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of CHST1 mRNA | CTD | PMID:27387713 | Chst1 | Rat | lipopolysaccharide | multiple interactions | ISO | CHST1 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of CHST1 mRNA | CTD | PMID:35811015 | Chst1 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of CHST1 mRNA | CTD | PMID:30047161 | Chst1 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of CHST1 gene | CTD | PMID:35440735 | Chst1 | Rat | methylparaben | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | methylparaben results in increased expression of CHST1 mRNA | CTD | PMID:17121429 | Chst1 | Rat | monosodium L-glutamate | multiple interactions | ISO | Chst1 (Mus musculus) | 6480464 | [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CHST1 mRNA | CTD | PMID:19001666 | Chst1 | Rat | N-Acetyl-S-(1,2-dichlorovinyl)-cysteine | affects expression | ISO | CHST1 (Homo sapiens) | 6480464 | S-1 and 2-dichlorovinyl-N-acetylcysteine affects the expression of CHST1 mRNA | CTD | PMID:16844155 | Chst1 | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of CHST1 mRNA | CTD | PMID:24810058 | Chst1 | Rat | ozone | multiple interactions | ISO | Chst1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of CHST1 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of CHST1 mRNA | CTD | PMID:34911549 | Chst1 | Rat | paracetamol | affects expression | ISO | Chst1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of CHST1 mRNA | CTD | PMID:17562736 | Chst1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of CHST1 mRNA | CTD | PMID:30723492 | Chst1 | Rat | paracetamol | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of CHST1 mRNA | CTD | PMID:29067470 | Chst1 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of CHST1 mRNA | CTD | PMID:32680482 | Chst1 | Rat | pentanal | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | pentanal results in increased expression of CHST1 mRNA | CTD | PMID:26079696 | Chst1 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of CHST1 mRNA | CTD | PMID:35163327 | Chst1 | Rat | perfluorooctanoic acid | increases expression | ISO | Chst1 (Mus musculus) | 6480464 | perfluorooctanoic acid results in increased expression of CHST1 mRNA | CTD | PMID:37422089 | Chst1 | Rat | permethrin | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | Permethrin results in increased expression of CHST1 mRNA | CTD | PMID:37047231 | Chst1 | Rat | propanal | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of CHST1 mRNA | CTD | PMID:26079696 | Chst1 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | CHST1 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of CHST1 mRNA | CTD | PMID:35811015 | Chst1 | Rat | silicon dioxide | decreases expression | ISO | Chst1 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of CHST1 mRNA | CTD | PMID:19073995 | Chst1 | Rat | silicon dioxide | decreases expression | ISO | CHST1 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased expression of CHST1 mRNA | CTD | PMID:25351596 | Chst1 | Rat | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of CHST1 mRNA | CTD | PMID:22431001 | Chst1 | Rat | sodium arsenite | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of CHST1 mRNA | CTD | PMID:29301061 | Chst1 | Rat | sodium fluoride | increases expression | EXP | | 6480464 | Sodium Fluoride results in increased expression of CHST1 mRNA | CTD | PMID:27257137 | Chst1 | Rat | sunitinib | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of CHST1 mRNA | CTD | PMID:31533062 | Chst1 | Rat | tetrachloromethane | decreases expression | ISO | Chst1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of CHST1 mRNA | CTD | PMID:17484886 | Chst1 | Rat | tetraphene | multiple interactions | ISO | Chst1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CHST1 mRNA | CTD | PMID:27858113 | Chst1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CHST1 mRNA | CTD | PMID:34492290 | Chst1 | Rat | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of CHST1 mRNA | CTD | PMID:30012374 | Chst1 | Rat | titanium dioxide | decreases methylation | ISO | Chst1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of CHST1 gene | CTD | PMID:35295148 | Chst1 | Rat | trimellitic anhydride | decreases expression | ISO | Chst1 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of CHST1 mRNA | CTD | PMID:19042947 | Chst1 | Rat | trovafloxacin | decreases expression | ISO | Chst1 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of CHST1 mRNA | CTD | PMID:35537566 | Chst1 | Rat | valproic acid | increases expression | ISO | CHST1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CHST1 mRNA | CTD | PMID:19101580 and PMID:29154799 | Chst1 | Rat | valproic acid | affects expression | ISO | CHST1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CHST1 mRNA | CTD | PMID:25979313 | |