Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tmem9 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TMEM9 mRNA] | CTD | PMID:31150632 | Tmem9 | Rat | 1,2-dichloroethane | decreases expression | ISO | Tmem9 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of TMEM9 mRNA | CTD | PMID:28189721 and PMID:28960355 | Tmem9 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Tmem9 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TMEM9 mRNA | CTD | PMID:22206623 | Tmem9 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Tmem9 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of TMEM9 mRNA | CTD | PMID:17555576 | Tmem9 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Tmem9 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TMEM9 mRNA | CTD | PMID:17942748 | Tmem9 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Tmem9 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of TMEM9 mRNA | CTD | PMID:17942748 | Tmem9 | Rat | 2,2',5,5'-tetrachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23829299 | Tmem9 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Tmem9 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TMEM9 mRNA | CTD | PMID:17942748 | Tmem9 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMEM9 mRNA | CTD | PMID:33387578 | Tmem9 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMEM9 mRNA | CTD | PMID:34747641 | Tmem9 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tmem9 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMEM9 mRNA | CTD | PMID:21570461 and PMID:24680724 | Tmem9 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TMEM9 mRNA | CTD | PMID:30047161 | Tmem9 | Rat | all-trans-retinoic acid | decreases expression | ISO | TMEM9 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of TMEM9 mRNA | CTD | PMID:33167477 | Tmem9 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of TMEM9 mRNA | CTD | PMID:30047161 | Tmem9 | Rat | Aroclor 1254 | increases expression | ISO | Tmem9 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of TMEM9 mRNA | CTD | PMID:23650126 | Tmem9 | Rat | atrazine | increases expression | ISO | TMEM9 (Homo sapiens) | 6480464 | Atrazine results in increased expression of TMEM9 mRNA | CTD | PMID:22378314 | Tmem9 | Rat | benzo[a]pyrene | affects methylation | ISO | TMEM9 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TMEM9 promoter | CTD | PMID:27901495 | Tmem9 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TMEM9 mRNA | CTD | PMID:25181051 | Tmem9 | Rat | cadmium atom | multiple interactions | ISO | TMEM9 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TMEM9 mRNA | CTD | PMID:35301059 | Tmem9 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of TMEM9 mRNA | CTD | PMID:33453195 | Tmem9 | Rat | cadmium dichloride | multiple interactions | ISO | TMEM9 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TMEM9 mRNA | CTD | PMID:35301059 | Tmem9 | Rat | CGP 52608 | multiple interactions | ISO | TMEM9 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TMEM9 gene] | CTD | PMID:28238834 | Tmem9 | Rat | chlorpyrifos | increases expression | ISO | Tmem9 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of TMEM9 mRNA | CTD | PMID:32715474 and PMID:37019170 | Tmem9 | Rat | cisplatin | increases expression | ISO | TMEM9 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TMEM9 mRNA | CTD | PMID:27594783 | Tmem9 | Rat | clofibrate | decreases expression | ISO | Tmem9 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of TMEM9 mRNA | CTD | PMID:23811191 | Tmem9 | Rat | cyclosporin A | decreases methylation | ISO | TMEM9 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of TMEM9 promoter | CTD | PMID:27989131 | Tmem9 | Rat | Dibutyl phosphate | affects expression | ISO | TMEM9 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TMEM9 mRNA | CTD | PMID:37042841 | Tmem9 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of TMEM9 mRNA | CTD | PMID:21266533 | Tmem9 | Rat | doxorubicin | increases expression | ISO | TMEM9 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of TMEM9 mRNA | CTD | PMID:29803840 | Tmem9 | Rat | fenthion | increases expression | ISO | Tmem9 (Mus musculus) | 6480464 | Fenthion results in increased expression of TMEM9 mRNA | CTD | PMID:34813904 | Tmem9 | Rat | folic acid | multiple interactions | ISO | Tmem9 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TMEM9 mRNA | CTD | PMID:22206623 | Tmem9 | Rat | FR900359 | decreases phosphorylation | ISO | TMEM9 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of TMEM9 protein | CTD | PMID:37730182 | Tmem9 | Rat | hydralazine | multiple interactions | ISO | TMEM9 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of TMEM9 mRNA | CTD | PMID:17183730 | Tmem9 | Rat | inulin | multiple interactions | ISO | Tmem9 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of TMEM9 mRNA | CTD | PMID:36331819 | Tmem9 | Rat | ivermectin | decreases expression | ISO | TMEM9 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TMEM9 protein | CTD | PMID:32959892 | Tmem9 | Rat | lead(0) | affects expression | ISO | TMEM9 (Homo sapiens) | 6480464 | Lead affects the expression of TMEM9 mRNA | CTD | PMID:28903495 | Tmem9 | Rat | methidathion | increases expression | ISO | Tmem9 (Mus musculus) | 6480464 | methidathion results in increased expression of TMEM9 mRNA | CTD | PMID:34813904 | Tmem9 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of TMEM9 mRNA | CTD | PMID:30047161 | Tmem9 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of TMEM9 gene | CTD | PMID:35440735 | Tmem9 | Rat | paracetamol | affects expression | ISO | Tmem9 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TMEM9 mRNA | CTD | PMID:17562736 | Tmem9 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TMEM9 mRNA | CTD | PMID:33387578 | Tmem9 | Rat | paracetamol | affects response to substance | ISO | TMEM9 (Homo sapiens) | 6480464 | TMEM9 gene polymorphism affects the susceptibility to Acetaminophen | CTD | PMID:26104854 | Tmem9 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tmem9 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of TMEM9 mRNA | CTD | PMID:36331819 | Tmem9 | Rat | pirinixic acid | decreases expression | ISO | Tmem9 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of TMEM9 mRNA | CTD | PMID:23811191 | Tmem9 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of TMEM9 mRNA | CTD | PMID:30047161 | Tmem9 | Rat | resveratrol | multiple interactions | ISO | TMEM9 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of TMEM9 mRNA | CTD | PMID:23557933 | Tmem9 | Rat | sodium arsenite | decreases expression | ISO | Tmem9 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of TMEM9 mRNA | CTD | PMID:37668303 | Tmem9 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of TMEM9 mRNA | CTD | PMID:19281266 | Tmem9 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of TMEM9 mRNA | CTD | PMID:30047161 | Tmem9 | Rat | sunitinib | increases expression | ISO | TMEM9 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of TMEM9 mRNA | CTD | PMID:31533062 | Tmem9 | Rat | tamoxifen | affects expression | ISO | Tmem9 (Mus musculus) | 6480464 | Tamoxifen affects the expression of TMEM9 mRNA | CTD | PMID:17555576 | Tmem9 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TMEM9 mRNA] | CTD | PMID:31150632 | Tmem9 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TMEM9 mRNA | CTD | PMID:31150632 | Tmem9 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TMEM9 mRNA | CTD | PMID:34492290 | Tmem9 | Rat | thiram | decreases expression | ISO | TMEM9 (Homo sapiens) | 6480464 | Thiram results in decreased expression of TMEM9 mRNA | CTD | PMID:38568856 | Tmem9 | Rat | tremolite asbestos | decreases expression | ISO | Tmem9 (Mus musculus) | 6480464 | tremolite results in decreased expression of TMEM9 mRNA | CTD | PMID:29279043 | Tmem9 | Rat | triptonide | decreases expression | ISO | Tmem9 (Mus musculus) | 6480464 | triptonide results in decreased expression of TMEM9 mRNA | CTD | PMID:33045310 | Tmem9 | Rat | valproic acid | multiple interactions | ISO | TMEM9 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of TMEM9 mRNA | CTD | PMID:17183730 | Tmem9 | Rat | valproic acid | increases expression | ISO | TMEM9 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TMEM9 mRNA | CTD | PMID:29154799 | Tmem9 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of TMEM9 mRNA | CTD | PMID:23034163 and PMID:23555832 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