Sh3glb2 (SH3 domain-containing GRB2-like endophilin B2) - Rat Genome Database

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Gene: Sh3glb2 (SH3 domain-containing GRB2-like endophilin B2) Rattus norvegicus
Analyze
Symbol: Sh3glb2
Name: SH3 domain-containing GRB2-like endophilin B2
RGD ID: 1305886
Description: Predicted to enable identical protein binding activity. Involved in postsynaptic neurotransmitter receptor internalization. Is active in glutamatergic synapse and postsynaptic endocytic zone. Orthologous to human SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2); PARTICIPATES IN endocytosis pathway; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: endophilin-B2; LOC311848; MGC105723; SH3 domain-containing GRB2-like protein B2; SH3-containing protein SH3GLB2; SH3-domain GRB2-like endophilin B2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8334,014,746 - 34,029,607 (-)NCBIGRCr8
mRatBN7.2313,616,936 - 13,631,785 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,616,938 - 13,631,757 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx316,688,459 - 16,703,281 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0325,273,425 - 25,288,245 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,519,111 - 23,533,963 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,909,231 - 8,924,066 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,909,236 - 8,924,032 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0314,262,005 - 14,276,841 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.439,388,827 - 9,403,628 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.139,389,126 - 9,403,928 (-)NCBI
Celera38,383,439 - 8,398,287 (-)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
cytosol  (IEA,ISO)
glutamatergic synapse  (IDA,IEP,IMP)
membrane  (IBA)
nucleoplasm  (IEA,ISO)
postsynaptic endocytic zone  (IDA,IMP)
synapse  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. CPG2 Recruits Endophilin B2 to the Cytoskeleton for Activity-Dependent Endocytosis of Synaptic Glutamate Receptors. Loebrich S, etal., Curr Biol. 2016 Feb 8;26(3):296-308. doi: 10.1016/j.cub.2015.11.071. Epub 2016 Jan 14.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11161816   PMID:12477932   PMID:20562859   PMID:25468996   PMID:27107012   PMID:28235806   PMID:29476059  


Genomics

Comparative Map Data
Sh3glb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8334,014,746 - 34,029,607 (-)NCBIGRCr8
mRatBN7.2313,616,936 - 13,631,785 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,616,938 - 13,631,757 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx316,688,459 - 16,703,281 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0325,273,425 - 25,288,245 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,519,111 - 23,533,963 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,909,231 - 8,924,066 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,909,236 - 8,924,032 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0314,262,005 - 14,276,841 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.439,388,827 - 9,403,628 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.139,389,126 - 9,403,928 (-)NCBI
Celera38,383,439 - 8,398,287 (-)NCBICelera
Cytogenetic Map3p12NCBI
SH3GLB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389129,007,036 - 129,028,331 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9129,007,036 - 129,028,331 (-)EnsemblGRCh38hg38GRCh38
GRCh379131,769,315 - 131,790,610 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,810,134 - 130,830,400 (-)NCBINCBI36Build 36hg18NCBI36
Build 349128,849,867 - 128,870,133NCBI
Celera9102,422,625 - 102,442,892 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9101,377,634 - 101,397,864 (-)NCBIHuRef
CHM1_19131,921,341 - 131,941,566 (-)NCBICHM1_1
T2T-CHM13v2.09141,210,470 - 141,231,788 (-)NCBIT2T-CHM13v2.0
Sh3glb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39230,234,789 - 30,249,380 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl230,234,821 - 30,249,349 (-)EnsemblGRCm39 Ensembl
GRCm38230,344,777 - 30,359,358 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl230,344,809 - 30,359,337 (-)EnsemblGRCm38mm10GRCm38
MGSCv37230,200,329 - 30,214,751 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36230,166,818 - 30,181,240 (-)NCBIMGSCv36mm8
Celera230,049,844 - 30,064,263 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.6NCBI
Sh3glb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,370,106 - 1,379,408 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555701,370,106 - 1,379,405 (-)NCBIChiLan1.0ChiLan1.0
SH3GLB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,324,917 - 10,345,291 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,327,264 - 10,347,635 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09100,131,458 - 100,151,869 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,791,970 - 128,806,576 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,791,948 - 128,806,578 (-)Ensemblpanpan1.1panPan2
SH3GLB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1954,636,610 - 54,656,724 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,635,870 - 54,656,720 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha953,832,165 - 53,852,272 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0955,557,623 - 55,577,763 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl955,557,506 - 55,577,761 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,319,184 - 54,339,329 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0954,631,394 - 54,651,531 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0954,724,706 - 54,744,838 (+)NCBIUU_Cfam_GSD_1.0
Sh3glb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,695,178 - 196,715,246 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,463,666 - 16,474,969 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,463,705 - 16,474,699 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3GLB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1269,312,825 - 269,332,344 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11269,313,788 - 269,332,351 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21303,329,912 - 303,348,485 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SH3GLB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,131,906 - 9,149,674 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,131,929 - 9,149,032 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666096408,001 - 426,673 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh3glb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247606,047,411 - 6,060,425 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247606,047,388 - 6,060,425 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sh3glb2
107 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:59
Interacting mature miRNAs:72
Transcripts:ENSRNOT00000023527
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)31043430624512004Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat

Markers in Region
RH134009  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2313,616,943 - 13,617,144 (+)MAPPERmRatBN7.2
Rnor_6.038,909,239 - 8,909,439NCBIRnor6.0
Rnor_5.0314,262,013 - 14,262,213UniSTSRnor5.0
RGSC_v3.439,388,835 - 9,389,035UniSTSRGSC3.4
Celera38,383,447 - 8,383,647UniSTS
Cytogenetic Map3p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001393780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001393781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_172010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC098064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC087652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000023527   ⟹   ENSRNOP00000023527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl313,616,941 - 13,631,738 (-)Ensembl
Rnor_6.0 Ensembl38,909,236 - 8,924,032 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085042   ⟹   ENSRNOP00000075076
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl313,616,938 - 13,631,756 (-)Ensembl
Rnor_6.0 Ensembl38,909,540 - 8,924,032 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100859   ⟹   ENSRNOP00000085000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl313,616,941 - 13,631,738 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103772   ⟹   ENSRNOP00000077030
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl313,616,943 - 13,631,757 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107109   ⟹   ENSRNOP00000089795
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl313,616,943 - 13,631,757 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109601   ⟹   ENSRNOP00000097875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl313,616,941 - 13,631,738 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116005   ⟹   ENSRNOP00000079486
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl313,616,941 - 13,631,738 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116758   ⟹   ENSRNOP00000084372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl313,616,943 - 13,631,757 (-)Ensembl
RefSeq Acc Id: NM_001393780   ⟹   NP_001380709
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,014,746 - 34,029,566 (-)NCBI
mRatBN7.2313,616,936 - 13,631,757 (-)NCBI
RefSeq Acc Id: NM_001393781   ⟹   NP_001380710
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,014,746 - 34,029,566 (-)NCBI
mRatBN7.2313,616,936 - 13,631,757 (-)NCBI
RefSeq Acc Id: NR_172010
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,014,746 - 34,029,566 (-)NCBI
mRatBN7.2313,616,936 - 13,631,757 (-)NCBI
RefSeq Acc Id: XM_006233819   ⟹   XP_006233881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,014,746 - 34,029,607 (-)NCBI
mRatBN7.2313,616,936 - 13,631,780 (-)NCBI
Rnor_6.038,909,231 - 8,924,064 (-)NCBI
Rnor_5.0314,262,005 - 14,276,841 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233822   ⟹   XP_006233884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,014,746 - 34,029,607 (-)NCBI
mRatBN7.2313,616,936 - 13,631,780 (-)NCBI
Rnor_6.038,909,231 - 8,924,063 (-)NCBI
Rnor_5.0314,262,005 - 14,276,841 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761661   ⟹   XP_008759883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,014,746 - 34,029,607 (-)NCBI
mRatBN7.2313,616,936 - 13,631,781 (-)NCBI
Rnor_6.038,909,231 - 8,924,066 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761662   ⟹   XP_008759884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,014,746 - 34,029,607 (-)NCBI
mRatBN7.2313,616,936 - 13,631,780 (-)NCBI
Rnor_6.038,909,231 - 8,924,063 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105239   ⟹   XP_038961167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,015,723 - 34,029,607 (-)NCBI
mRatBN7.2313,617,904 - 13,631,780 (-)NCBI
RefSeq Acc Id: XM_063283947   ⟹   XP_063140017
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,014,746 - 34,029,607 (-)NCBI
RefSeq Acc Id: XM_063283948   ⟹   XP_063140018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,014,746 - 34,025,639 (-)NCBI
RefSeq Acc Id: XM_063283949   ⟹   XP_063140019
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,015,723 - 34,029,607 (-)NCBI
RefSeq Acc Id: XM_063283950   ⟹   XP_063140020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,018,485 - 34,029,607 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001380709 (Get FASTA)   NCBI Sequence Viewer  
  NP_001380710 (Get FASTA)   NCBI Sequence Viewer  
  XP_006233881 (Get FASTA)   NCBI Sequence Viewer  
  XP_006233884 (Get FASTA)   NCBI Sequence Viewer  
  XP_008759883 (Get FASTA)   NCBI Sequence Viewer  
  XP_008759884 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961167 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140017 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140018 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140019 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140020 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87652 (Get FASTA)   NCBI Sequence Viewer  
  EDL93317 (Get FASTA)   NCBI Sequence Viewer  
  EDL93318 (Get FASTA)   NCBI Sequence Viewer  
  EDL93319 (Get FASTA)   NCBI Sequence Viewer  
  EDL93320 (Get FASTA)   NCBI Sequence Viewer  
  EDL93321 (Get FASTA)   NCBI Sequence Viewer  
  EDL93322 (Get FASTA)   NCBI Sequence Viewer  
  EDL93323 (Get FASTA)   NCBI Sequence Viewer  
  EDL93324 (Get FASTA)   NCBI Sequence Viewer  
  EDL93325 (Get FASTA)   NCBI Sequence Viewer  
  EDL93326 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000023527.7
  ENSRNOP00000075076.2
  ENSRNOP00000077030.1
  ENSRNOP00000079486.1
  ENSRNOP00000084372.1
  ENSRNOP00000085000.1
  ENSRNOP00000089795.1
  ENSRNOP00000097875.1
GenBank Protein Q5PPJ9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_006233884   ⟸   XM_006233822
- Peptide Label: isoform X4
- UniProtKB: A6JTX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233881   ⟸   XM_006233819
- Peptide Label: isoform X3
- UniProtKB: A0A0G2K9P4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759883   ⟸   XM_008761661
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZ43 (UniProtKB/TrEMBL),   A0A8I6GM93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759884   ⟸   XM_008761662
- Peptide Label: isoform X5
- UniProtKB: A0A8I6GHN4 (UniProtKB/TrEMBL),   A6JTX3 (UniProtKB/TrEMBL),   A6JTX1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023527   ⟸   ENSRNOT00000023527
Ensembl Acc Id: ENSRNOP00000075076   ⟸   ENSRNOT00000085042
RefSeq Acc Id: XP_038961167   ⟸   XM_039105239
- Peptide Label: isoform X8
Ensembl Acc Id: ENSRNOP00000089795   ⟸   ENSRNOT00000107109
Ensembl Acc Id: ENSRNOP00000079486   ⟸   ENSRNOT00000116005
Ensembl Acc Id: ENSRNOP00000077030   ⟸   ENSRNOT00000103772
Ensembl Acc Id: ENSRNOP00000097875   ⟸   ENSRNOT00000109601
Ensembl Acc Id: ENSRNOP00000085000   ⟸   ENSRNOT00000100859
Ensembl Acc Id: ENSRNOP00000084372   ⟸   ENSRNOT00000116758
RefSeq Acc Id: NP_001380710   ⟸   NM_001393781
- Peptide Label: isoform 1
- UniProtKB: A6JTX4 (UniProtKB/TrEMBL),   A0A0G2K9P4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001380709   ⟸   NM_001393780
- Peptide Label: isoform 2
- UniProtKB: A0A0G2K9P4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140017   ⟸   XM_063283947
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063140018   ⟸   XM_063283948
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063140019   ⟸   XM_063283949
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063140020   ⟸   XM_063283950
- Peptide Label: isoform X9
Protein Domains
BAR   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5PPJ9-F1-model_v2 AlphaFold Q5PPJ9 1-404 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691957
Promoter ID:EPDNEW_R2481
Type:initiation region
Name:Sh3glb2_1
Description:SH3 domain-containing GRB2-like endophilin B2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.038,924,112 - 8,924,172EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305886 AgrOrtholog
BioCyc Gene G2FUF-50220 BioCyc
Ensembl Genes ENSRNOG00000017295 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000023527.8 UniProtKB/TrEMBL
  ENSRNOT00000085042.2 UniProtKB/TrEMBL
  ENSRNOT00000100859.1 UniProtKB/TrEMBL
  ENSRNOT00000103772.1 UniProtKB/TrEMBL
  ENSRNOT00000107109.1 UniProtKB/TrEMBL
  ENSRNOT00000109601.1 UniProtKB/TrEMBL
  ENSRNOT00000116005.1 UniProtKB/TrEMBL
  ENSRNOT00000116758.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7312960 IMAGE-MGC_LOAD
InterPro AH/BAR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BAR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endophilin_B2_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endophilin_SH3RF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:105723 IMAGE-MGC_LOAD
NCBI Gene 311848 ENTREZGENE
PANTHER DREBRIN-LIKE PROTEIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 DOMAIN-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sh3glb2 PhenoGen
PROSITE BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017295 RatGTEx
SMART BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K9P4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y0M5_RAT UniProtKB/TrEMBL
  A0A8I5ZMU1_RAT UniProtKB/TrEMBL
  A0A8I5ZYB8_RAT UniProtKB/TrEMBL
  A0A8I5ZZ43 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GHN4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GM93 ENTREZGENE, UniProtKB/TrEMBL
  A6JTX1 ENTREZGENE, UniProtKB/TrEMBL
  A6JTX3 ENTREZGENE, UniProtKB/TrEMBL
  A6JTX4 ENTREZGENE, UniProtKB/TrEMBL
  A6JTX6_RAT UniProtKB/TrEMBL
  A6JTX7_RAT UniProtKB/TrEMBL
  A6JTX8_RAT UniProtKB/TrEMBL
  A6JTX9_RAT UniProtKB/TrEMBL
  D4A7V1_RAT UniProtKB/TrEMBL
  Q5PPJ9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-04 Sh3glb2  SH3 domain-containing GRB2-like endophilin B2  Sh3glb2  SH3-domain GRB2-like endophilin B2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Sh3glb2  SH3-domain GRB2-like endophilin B2  Sh3glb2_predicted  SH3-domain GRB2-like endophilin B2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sh3glb2_predicted  SH3-domain GRB2-like endophilin B2 (predicted)      Symbol and Name status set to approved 70820 APPROVED