FBLIM1 (filamin binding LIM protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: FBLIM1 (filamin binding LIM protein 1) Canis lupus familiaris
Analyze
Symbol: FBLIM1
Name: filamin binding LIM protein 1
RGD ID: 12161489
Description: ENCODES a protein that exhibits filamin binding (inferred); metal ion binding (inferred); INVOLVED IN cell adhesion (inferred); cell-cell adhesion (inferred); regulation of cell shape (inferred); PARTICIPATES IN integrin mediated signaling pathway; FOUND IN cell junction (inferred); cell periphery (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: filamin-binding LIM protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,820,129 - 81,837,617 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,821,291 - 81,838,306 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha278,358,519 - 78,382,681 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0282,468,984 - 82,493,387 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl282,468,997 - 82,491,099 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1279,222,455 - 79,246,609 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0280,240,491 - 80,264,810 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0281,306,542 - 81,330,706 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell junction  (IEA)
cell periphery  (IEA)
cytoplasm  (IEA)
focal adhesion  (IBA,IEA)
stress fiber  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FBLIM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,820,129 - 81,837,617 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,821,291 - 81,838,306 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha278,358,519 - 78,382,681 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0282,468,984 - 82,493,387 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl282,468,997 - 82,491,099 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1279,222,455 - 79,246,609 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0280,240,491 - 80,264,810 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0281,306,542 - 81,330,706 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
FBLIM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38115,756,638 - 15,786,589 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl115,756,604 - 15,786,594 (+)Ensemblhg38GRCh38
GRCh37116,083,133 - 16,113,084 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36115,957,842 - 15,985,671 (+)NCBIBuild 36Build 36hg18NCBI36
Celera114,568,272 - 14,596,101 (+)NCBICelera
Cytogenetic Map1p36.21NCBI
HuRef114,604,147 - 14,633,154 (+)NCBIHuRef
CHM1_1115,883,844 - 15,911,675 (+)NCBICHM1_1
T2T-CHM13v2.0115,201,378 - 15,231,333 (+)NCBIT2T-CHM13v2.0
Fblim1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,303,373 - 141,333,351 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4141,303,373 - 141,333,407 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384141,576,062 - 141,606,052 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,576,062 - 141,606,096 (-)Ensemblmm10GRCm38
MGSCv374141,131,977 - 141,161,967 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364140,849,005 - 140,868,028 (-)NCBIMGSCv36mm8
Celera4143,398,852 - 143,428,836 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map474.64NCBI
Fblim1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85159,167,004 - 159,198,578 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5159,167,004 - 159,196,853 (-)EnsemblGRCr8
mRatBN7.25153,883,945 - 153,915,524 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,883,960 - 153,913,757 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5156,568,849 - 156,598,883 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05158,342,136 - 158,372,165 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05158,331,314 - 158,361,338 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd5158,780,365 - 158,810,411 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive5160,770,651 - 160,800,687 (-)NCBILyon_Normotensive
Lyon_Hypertensive5159,946,148 - 159,976,187 (-)NCBILyon_Hypertensive
F344_StmMcwi5153,514,919 - 153,544,953 (-)NCBIF344_StmMcwi
Rnor_6.05160,122,466 - 160,158,921 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5160,122,425 - 160,158,386 (-)Ensemblrn6Rnor6.0
Rnor_5.05163,841,377 - 163,867,441 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45160,468,558 - 160,495,015 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5152,241,216 - 152,267,207 (-)NCBICelera
RGSC_v3.15160,478,745 - 160,505,203 (-)NCBI
Cytogenetic Map5q36NCBI
Fblim1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555272,400,218 - 2,415,051 (-)Ensembl
ChiLan1.0NW_0049555272,399,804 - 2,418,160 (-)NCBIChiLan1.0ChiLan1.0
FBLIM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21211,129,565 - 211,159,464 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11210,378,150 - 210,408,064 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0114,898,987 - 14,928,887 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1115,890,592 - 15,921,557 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl115,890,600 - 15,921,558 (+)EnsemblpanPan2panpan1.1
Fblim1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505837,559,213 - 37,575,078 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364743,384,043 - 3,398,907 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364743,386,279 - 3,398,880 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBLIM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl674,929,932 - 74,966,942 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1674,929,830 - 74,964,166 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,342,884 - 69,375,270 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBLIM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120116,518,768 - 116,545,907 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20116,518,679 - 116,546,280 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605420,052,373 - 20,081,897 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fblim1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1116,546,267 - 16,574,574 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in FBLIM1
260 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_038464271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038464272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038471028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038471029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038531901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038531902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038596165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038596166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038660248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038660249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_859994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000025606   ⟹   ENSCAFP00000023779
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl281,821,291 - 81,838,306 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000063792   ⟹   ENSCAFP00000046396
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl281,821,291 - 81,837,597 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845008855   ⟹   ENSCAFP00845006977
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl282,468,997 - 82,491,099 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845008859   ⟹   ENSCAFP00845006981
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl282,468,997 - 82,486,055 (-)Ensembl
RefSeq Acc Id: XM_038464271   ⟹   XP_038320199
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha278,358,519 - 78,380,404 (-)NCBI
RefSeq Acc Id: XM_038464272   ⟹   XP_038320200
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha278,358,519 - 78,382,681 (-)NCBI
RefSeq Acc Id: XM_038471028   ⟹   XP_038326956
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1279,222,455 - 79,244,334 (-)NCBI
RefSeq Acc Id: XM_038471029   ⟹   XP_038326957
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1279,222,455 - 79,246,609 (-)NCBI
RefSeq Acc Id: XM_038531901   ⟹   XP_038387829
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0281,306,542 - 81,328,428 (-)NCBI
RefSeq Acc Id: XM_038531902   ⟹   XP_038387830
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0281,306,542 - 81,330,706 (-)NCBI
RefSeq Acc Id: XM_038596165   ⟹   XP_038452093
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0280,240,491 - 80,262,545 (-)NCBI
RefSeq Acc Id: XM_038596166   ⟹   XP_038452094
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0280,240,491 - 80,264,810 (-)NCBI
RefSeq Acc Id: XM_038660248   ⟹   XP_038516176
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0282,468,984 - 82,491,101 (-)NCBI
RefSeq Acc Id: XM_038660249   ⟹   XP_038516177
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0282,468,984 - 82,493,387 (-)NCBI
Ensembl Acc Id: ENSCAFP00000023779   ⟸   ENSCAFT00000025606
Ensembl Acc Id: ENSCAFP00000046396   ⟸   ENSCAFT00000063792
RefSeq Acc Id: XP_038326957   ⟸   XM_038471029
RefSeq Acc Id: XP_038326956   ⟸   XM_038471028
RefSeq Acc Id: XP_038452094   ⟸   XM_038596166
RefSeq Acc Id: XP_038452093   ⟸   XM_038596165
RefSeq Acc Id: XP_038516177   ⟸   XM_038660249
- UniProtKB: A0A8C0Q360 (UniProtKB/TrEMBL),   A0A8I3RTV4 (UniProtKB/TrEMBL),   A0A8C0NGJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038516176   ⟸   XM_038660248
- UniProtKB: A0A8C0Q360 (UniProtKB/TrEMBL),   A0A8I3RTV4 (UniProtKB/TrEMBL),   A0A8C0NGJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038320200   ⟸   XM_038464272
- UniProtKB: A0A8C0Q360 (UniProtKB/TrEMBL),   A0A8I3RTV4 (UniProtKB/TrEMBL),   A0A8C0NGJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038320199   ⟸   XM_038464271
- UniProtKB: A0A8C0Q360 (UniProtKB/TrEMBL),   A0A8I3RTV4 (UniProtKB/TrEMBL),   A0A8C0NGJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038387830   ⟸   XM_038531902
- UniProtKB: A0A8C0NGJ2 (UniProtKB/TrEMBL),   A0A8C0Q360 (UniProtKB/TrEMBL),   A0A8I3RTV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038387829   ⟸   XM_038531901
- UniProtKB: A0A8C0NGJ2 (UniProtKB/TrEMBL),   A0A8C0Q360 (UniProtKB/TrEMBL),   A0A8I3RTV4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845006977   ⟸   ENSCAFT00845008855
Ensembl Acc Id: ENSCAFP00845006981   ⟸   ENSCAFT00845008859
Protein Domains
LIM zinc-binding

Promoters
RGD ID:13682645
Promoter ID:EPDNEW_C713
Type:single initiation site
Name:FBLIM1_1
Description:filamin binding LIM protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1281,837,599 - 81,837,659EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016138 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030012627 UniProtKB/TrEMBL
  ENSCAFG00040003531 UniProtKB/TrEMBL
  ENSCAFG00845004948 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000025606.5 UniProtKB/TrEMBL
  ENSCAFT00000063792.2 UniProtKB/TrEMBL
  ENSCAFT00030023503.1 UniProtKB/TrEMBL
  ENSCAFT00040006723.1 UniProtKB/TrEMBL
  ENSCAFT00040006727.1 UniProtKB/TrEMBL
  ENSCAFT00845008855 ENTREZGENE
  ENSCAFT00845008855.1 UniProtKB/TrEMBL
  ENSCAFT00845008859.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
InterPro Znf_LIM UniProtKB/TrEMBL
NCBI Gene FBLIM1 ENTREZGENE
PANTHER FILAMIN-BINDING LIM PROTEIN 1 UniProtKB/TrEMBL
  ZYX102 PROTEIN UniProtKB/TrEMBL
Pfam LIM UniProtKB/TrEMBL
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
SMART LIM UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt A0A8C0NGJ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PYZ2_CANLF UniProtKB/TrEMBL
  A0A8C0Q360 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MVW4_CANLF UniProtKB/TrEMBL
  A0A8I3RTV4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40749 ENTREZGENE