PAX4 (paired box 4) - Rat Genome Database

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Pathways
Gene: PAX4 (paired box 4) Pan paniscus
Analyze
Symbol: PAX4
Name: paired box 4
RGD ID: 11973670
Description: ENCODES a protein that exhibits double-stranded DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN circadian rhythm (ortholog); negative regulation of apoptotic process (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH diabetes mellitus (ortholog); diabetic ketoacidosis (ortholog); hyperglycemia (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: paired box protein Pax-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26164,469,513 - 164,483,506 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1716,479,764 - 16,492,993 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07119,605,924 - 119,613,579 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17132,260,859 - 132,266,384 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7132,260,859 - 132,268,516 (-)EnsemblpanPan2panpan1.1
JBrowse:




References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PAX4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26164,469,513 - 164,483,506 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1716,479,764 - 16,492,993 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07119,605,924 - 119,613,579 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17132,260,859 - 132,266,384 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7132,260,859 - 132,268,516 (-)EnsemblpanPan2panpan1.1
PAX4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387127,610,292 - 127,618,142 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7127,610,292 - 127,618,142 (-)Ensemblhg38GRCh38
GRCh377127,250,346 - 127,258,196 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367127,037,582 - 127,043,016 (-)NCBIBuild 36Build 36hg18NCBI36
Build 347126,844,296 - 126,849,731NCBI
Celera7122,054,068 - 122,059,509 (-)NCBICelera
Cytogenetic Map7q32.1NCBI
HuRef7121,611,239 - 121,616,685 (-)NCBIHuRef
CHM1_17127,183,648 - 127,189,085 (-)NCBICHM1_1
T2T-CHM13v2.07128,921,978 - 128,929,835 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27126,633,785 - 126,639,226 (-)NCBI
Pax4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39628,442,333 - 28,449,339 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl628,442,333 - 28,449,352 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38628,442,334 - 28,449,340 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl628,442,334 - 28,449,353 (-)Ensemblmm10GRCm38
MGSCv37628,392,334 - 28,399,340 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36628,392,350 - 28,399,285 (-)NCBIMGSCv36mm8
Celera628,449,374 - 28,456,380 (-)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map611.99NCBI
Pax4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8458,023,873 - 58,032,265 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl458,023,914 - 58,028,858 (-)EnsemblGRCr8
mRatBN7.2457,058,453 - 57,065,995 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl457,058,462 - 57,063,408 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx462,041,683 - 62,046,628 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0457,957,636 - 57,962,575 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0456,359,732 - 56,364,677 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd459,769,254 - 59,774,198 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive457,168,294 - 57,173,221 (-)NCBILyon_Normotensive
Lyon_Hypertensive457,761,888 - 57,766,823 (-)NCBILyon_Hypertensive
F344_StmMcwi457,534,376 - 57,539,321 (-)NCBIF344_StmMcwi
Rnor_6.0455,735,640 - 55,753,461 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl455,735,682 - 55,740,627 (-)Ensemblrn6Rnor6.0
Rnor_5.0455,483,073 - 55,501,087 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4455,313,500 - 55,318,995 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera452,169,993 - 52,174,904 (-)NCBICelera
RGSC_v3.1455,563,656 - 55,569,152 (-)NCBI
Cytogenetic Map4q22NCBI
Pax4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554798,660,089 - 8,664,463 (-)Ensembl
ChiLan1.0NW_0049554798,660,089 - 8,664,463 (-)NCBIChiLan1.0ChiLan1.0
PAX4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,714,251 - 8,719,387 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,714,949 - 8,719,371 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha148,405,492 - 8,412,207 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0148,486,208 - 8,492,923 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl148,486,089 - 8,492,911 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1148,690,433 - 8,697,148 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0148,424,792 - 8,431,504 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,578,658 - 8,585,374 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pax4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511853,683,725 - 53,724,528 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647914,807,538 - 14,812,575 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647914,807,503 - 14,812,575 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAX4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1820,673,114 - 20,680,287 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11820,675,874 - 20,680,315 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21821,676,916 - 21,683,984 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PAX4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12196,425,496 - 96,435,846 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2196,425,656 - 96,429,874 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660426,977,047 - 6,981,546 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pax4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247838,340,098 - 8,344,371 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247838,340,098 - 8,344,371 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pax4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v16111,087,172 - 111,094,699 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000042955   ⟹   ENSPPAP00000020167
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7132,260,859 - 132,266,384 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000042961   ⟹   ENSPPAP00000020174
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7132,261,378 - 132,268,516 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000042970   ⟹   ENSPPAP00000020183
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7132,262,372 - 132,265,585 (-)Ensembl
RefSeq Acc Id: XM_003806049   ⟹   XP_003806097
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26164,469,513 - 164,477,553 (-)NCBI
NHGRI_mPanPan1716,479,764 - 16,487,804 (-)NCBI
Mhudiblu_PPA_v07119,605,924 - 119,613,579 (-)NCBI
PanPan1.17132,260,859 - 132,266,384 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055115368   ⟹   XP_054971343
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26164,470,026 - 164,483,506 (-)NCBI
NHGRI_mPanPan1716,480,277 - 16,492,993 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003806097 (Get FASTA)   NCBI Sequence Viewer  
  XP_054971343 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000020167.1
  ENSPPAP00000020174.1
  ENSPPAP00000020183.1
  ENSPPAP00050025256
RefSeq Acc Id: XP_003806097   ⟸   XM_003806049
- UniProtKB: A0A2R9AS32 (UniProtKB/TrEMBL),   A0A2R9AYP1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000020167   ⟸   ENSPPAT00000042955
Ensembl Acc Id: ENSPPAP00000020174   ⟸   ENSPPAT00000042961
Ensembl Acc Id: ENSPPAP00000020183   ⟸   ENSPPAT00000042970
RefSeq Acc Id: XP_054971343   ⟸   XM_055115368
- UniProtKB: A0A2R9AS32 (UniProtKB/TrEMBL),   A0A2R9AYP1 (UniProtKB/TrEMBL)
Protein Domains
Homeobox   Paired


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033297 Ensembl, UniProtKB/TrEMBL
  ENSPPAG00050018724 ENTREZGENE
Ensembl Transcript ENSPPAT00000042955.1 UniProtKB/TrEMBL
  ENSPPAT00000042961.1 UniProtKB/TrEMBL
  ENSPPAT00000042970.1 UniProtKB/TrEMBL
  ENSPPAT00050039523 ENTREZGENE
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  PAIRED_DNA-bd_dom UniProtKB/TrEMBL
  Paired_dom UniProtKB/TrEMBL
  PAX_fam UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report pps:100985809 UniProtKB/TrEMBL
NCBI Gene PAX4 ENTREZGENE
PANTHER PTHR45636 UniProtKB/TrEMBL
  PTHR45636:SF8 UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
  PAX UniProtKB/TrEMBL
PRINTS PAIREDBOX UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
  PAIRED_1 UniProtKB/TrEMBL
  PAIRED_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
  PAX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A2R9AS32 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ASL4_PANPA UniProtKB/TrEMBL
  A0A2R9AYP1 ENTREZGENE, UniProtKB/TrEMBL