| 11755446 | ENAM | enamelin | ENCODES a protein that exhibits structural constituent of tooth enamel (inferred); INVOLVED IN ameloblast differentiation (ortholog); amelogenesis (ortholog); odontogenesis of dentin-containing tooth (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog) ; amelogenesis imperfecta type 1B (ortholog); amelogenesis imperfecta type 1C (ortholog); FOUND IN extracellular matrix (inferred) | 4 | 53574316 | 53592465 | Bonobo | 19 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 11784439 | AMBN | ameloblastin | ENCODES a protein that exhibits growth factor activity (inferred); structural constituent of tooth enamel (inferred); INVOLVED IN regulation of cell population proliferation (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 1F (ortholog); BCARD syndrome ( ortholog); osteoporosis-pseudoglioma syndrome (ortholog) | 4 | 53616553 | 53631566 | Bonobo | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 11840196 | AMELY | amelogenin Y-linked | ENCODES a protein that exhibits calcium ion binding (ortholog); growth factor activity (ortholog); hydroxyapatite binding (ortholog); INVOLVED IN amelogenesis (ortholog); cell adhesion (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis im perfecta type 1E (ortholog); autosomal dominant hypocalcemia (ortholog); male infertility (ortholog); FOUND IN basement membrane (ortholog); cell surface (ortholog); endocytic vesicle (ortholog) | X | 3898819 | 3930686 | Bonobo | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 11684551 | AMTN | amelotin | INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (ortholog); FOUND IN basement membrane (inferred); cell-cell junction (inferred); extracellular mat rix (inferred) | 4 | 53691674 | 53705831 | Bonobo | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 11922291 | CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | ENCODES a protein that exhibits magnesium ion transmembrane transporter activity (inferred); sodium ion transmembrane transporter activity (inferred); transmembrane transporter activity (inferred); INVOLVED IN enamel mineralization (ortholog); magnesium ion home ostasis (ortholog); magnesium ion transport (ortholog); ASSOCIATED WITH Amaurosis Hypertrichosis (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN dendrite (ortholog); neuronal cell body (ortholog) | 2A | 102503084 | 102553029 | Bonobo | 33 | description | gene, protein-coding, MODEL [RefSeq] |
| 11791927 | CTBP1 | C-terminal binding protein 1 | ENCODES a protein that exhibits chromatin binding (ortholog); lncRNA binding (ortholog); PDZ domain binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); Notch signaling pathway (ortholog); presynapse to nucleus signaling pathway (ortholog); PARTICIPAT ES IN Notch signaling pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); genetic disease (ortholog); HYPOTONIA, ATAXIA, DEVELOPMENTAL DELAY, AND TOOTH ENAMEL DEFECT SYNDROME (ortholog); FOUND IN cytoplasm (ortholog); extrinsic component of presynaptic endocytic zone membrane (ortholog); GABA-ergic synapse (ortholog) | 4 | 1354806 | 1393244 | Bonobo | 97 | description | gene, protein-coding, MODEL [RefSeq] |
| 11974153 | DMP1 | dentin matrix acidic phosphoprotein 1 | ENCODES a protein that exhibits calcium ion binding (ortholog); Hsp70 protein binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell-substrate adhesion (ortholog); regulation of enamel mineralization (ortholog); ASSOCIATED WITH autosomal recessive hypophosphatemic rickets (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); extracellular matrix (inferred); nucleus (inferred) | 4 | 79943709 | 79957430 | Bonobo | 20 | description | gene, protein-coding, MODEL [RefSeq] |
| 11865837 | FAM20A | FAM20A golgi associated secretory pathway pseudokinase | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN enamel mineralization (ortholog); positive regulation of protein phosphorylation (ortholog); response to bacterium (ortholog); ASSOCIATED WITH amelogenesis imperfect a type 1G (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (inferred); endoplasmic reticulum (inferred); extracellular space (inferred) | 17 | 62474317 | 62537800 | Bonobo | 27 | description | gene, protein-coding, MODEL [RefSeq] |
| 11955703 | FAM20C | FAM20C golgi associated secretory pathway kinase | ENCODES a protein that exhibits calcium ion binding (ortholog); manganese ion binding (ortholog); protease binding (ortholog); INVOLVED IN biomineral tissue development (ortholog); dentinogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amel ogenesis imperfecta (ortholog); COVID-19 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); Golgi membrane (ortholog) | 7 | 311468 | 394623 | Bonobo | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 11691152 | FOSL2 | FOS like 2, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN alveolar secondary septum development (ortholog); B cell differentiation (ortholog); B cell proliferation (ortholog); ASSOCIATED WITH APLA SIA CUTIS-ENAMEL DYSPLASIA SYNDROME (ortholog); colon adenocarcinoma (ortholog); colorectal cancer (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); transcription factor AP-1 complex (inferred) | 2A | 28392328 | 28416838 | Bonobo | 140 | description | gene, protein-coding, MODEL [RefSeq] |
| 11955895 | KLK4 | kallikrein related peptidase 4 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); peptidase activity (inferred); INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); extracellular matrix disassembly (ortholog); ASSOCIATED WITH amelog enesis imperfecta (ortholog); amelogenesis imperfecta type 2A1 (ortholog); breast cancer (ortholog); FOUND IN extracellular region (inferred); secretory granule (inferred) | 19 | 47849158 | 47876522 | Bonobo | 30 | description | gene, protein-coding, MODEL [RefSeq] |
| 11764646 | LOC100991737 | putative adhesion G protein-coupled receptor F2P | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); gene expression (ortholog); ASSOCIATED WITH autistic diso rder (ortholog); FOUND IN membrane (inferred) | 6 | 47239514 | 47279734 | Bonobo | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 11671420 | ODAPH | odontogenesis associated phosphoprotein | INVOLVED IN positive regulation of biomineral tissue development (inferred); positive regulation of enamel mineralization (inferred); ASSOCIATED WITH amelogenesis imperfecta hypomaturation type 2A4 (ortholog) | 4 | 48640355 | 48649546 | Bonobo | 7 | description | gene, protein-coding, MODEL [RefSeq] |
| 11757610 | PPARA | peroxisome proliferator activated receptor alpha | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); MDM2/MDM4 family protein binding (ortholog); mitogen-activated protein kinase kinase kinase binding (ortholog); INVOLVED IN behavioral response to nicotine (ortholog); cellular response to fructose stimulus (ortholo g); enamel mineralization (ortholog); ASSOCIATED WITH abdominal obesity-metabolic syndrome (ortholog); acute kidney tubular necrosis (ortholog); alcohol use disorder (ortholog); FOUND IN nucleus (ortholog) | | | | Bonobo | 224 | description | gene, protein-coding, MODEL [RefSeq] |
| 11829292 | STIM1 | stromal interaction molecule 1 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); channel activator activity (ortholog); identical protein binding (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); detection of calcium ion (ortholog); enam '>enamel mineralization (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH colorectal cancer (ortholog); common variable immunodeficiency 10 (ortholog); congenital structural myopathy (ortholog); FOUND IN cortical endoplasmic reticulum (ortholog); growth cone (ortholog); plasma membrane (ortholog) | 11 | 3726501 | 3954951 | Bonobo | 109 | description | gene, protein-coding, MODEL [RefSeq] |
| 11970046 | WDR72 | WD repeat domain 72 | INVOLVED IN ameloblast differentiation (ortholog); amelogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta hypomaturation type 2A3 (ortholog); amelogenesis imperfecta type 1C (ortholo g); FOUND IN endosome (ortholog); extracellular region (ortholog); nucleus (ortholog) | 15 | 32449840 | 32695815 | Bonobo | 40 | description | gene, protein-coding, MODEL [RefSeq] |